Database Construction for Two-Dimensional Material-Substrate Interfaces

Interfacial structures and interactions of two-dimensional(2D)materials on solid substrates are of fundamental importance for fabrications and applications of 2D materials.However,selection of a suitable solid substrate to grow a 2D material,determination and control of 2D material-substrate interface remain a big challenge due to the large diversity of possible configurations.Here,we propose a computational framework to select an appropriate substrate for epitaxial growth of 2D material and to predict possible 2D material-substrate interface structures and orientations using density functional theory calculations performed for all non-equivalent atomic structures satisfying the symmetry constraints.The approach is validated by the correct prediction of three experimentally reported 2D material-substrate interface systems with only the given information of two parent materials.Several possible interface configurations are also proposed based on this approach.We therefore construct a database that contains these interface systems and has been continuously expanding.This database serves as preliminary guidance for epitaxial growth and stabilization of new materials in experiments.

Expert consensus on the diagnosis, treatment, and prevention of respiratory syncytial virus infections in children

Background Respiratory syncytial virus(RSV)is the leading global cause of respiratory infections and is responsible for about 3 million hospitalizations and more than 100,000 deaths annually in children younger than 5 years,representing a major global healthcare burden.There is a great unmet need for new agents and universal strategies to prevent RSV infections in early life.A multidisciplinary consensus development group comprising experts in epidemiology,infectious diseases,respiratory medicine,and methodology aims to develop the current consensus to address clinical issues of RSV infections in children.Data sources The evidence searches and reviews were conducted using electronic databases,including PubMed,Embase,Web of Science,and the Cochrane Library,using variations in terms for"respiratory syncytial virus","RSV","lower respiratory tract infection","bronchiolitis","acute","viral pneumonia","neonatal","infant""children",and"pediatric".Results Evidence-based recommendations regarding diagnosis,treatment,and prevention were proposed with a high degree of consensus.Although supportive care remains the cornerstone for the management of RSV infections,new monoclonal antibodies,vaccines,drug therapies,and viral surveillance techniques are being rolled out.Conclusions This consensus,based on international and national scientific evidence,reinforces the current recommendations and integrates the recent advances for optimal care and prevention of RSV infections.Further improvements in the management of RSV infections will require generating the highest quality of evidence through rigorously designed studies that possess little bias and sufficient capacity to identify clinically meaningful end points.

Alkali cation intercalation manganese phosphate hydrate boosting electrochemical kinetics for pseudocapacitive energy storage

New insight into the effect on the alkali cations of Liþ,Naþ,and Kþpre-intercalated between adjacent layers of Mn3(PO4)2$3H2O towards the charge storage mechanism and their electrochemical kinetics of intercalation/deintercalation in three alkali electrolytes is demonstrated.The electrochemical perfor-mance of the designed LieMn3(PO4)2$3H2O material outperforms that most of Mn-based pseudocapa-citive electrode materials.The designed unique stratified structure is attractive for quick charge migration,which confirms that the appropriate pre-intercalation of alkali cation between layers is an efficient strategy to improve kinetics for the high-power density pseudocapacitive supercapacitor energy storage application.