Regulation of phase structure has been recognized as one of the most effective ways to fabricate self-healing polymers with high mechanical strength.The mechanical properties of the resultant polymers are certainly af...Regulation of phase structure has been recognized as one of the most effective ways to fabricate self-healing polymers with high mechanical strength.The mechanical properties of the resultant polymers are certainly affected by the size of separated phase domain.However,the study on this aspect is absence,because it can hardly exclude the influence of variation in monomer proportion required for tuning the separated phase size.Here,we report the first study on tuning the phase size through reversible addition-fragmentation chain transfer(RAFT)polymerization without changing the proportion of monomers.As expected,the size of separated phase has been successfully mediated from 15 nm to 9 nm by tuning the molecular weight of the chain transfer agent.It is found that the mechanical strength and the self-healing efficiency of the resultant polymers increase simultaneously with the decrease of phase size.The study on the formation kinetics of hydrogen bonds reveals that the decrease of phase size can facilitate the re-bonding rate of hydrogen bonds,even if the migration of polymer chains is restricted.展开更多
As a morphological sub-type of multiple myeloma(MM),anaplastic myeloma(AM),which includes anaplastic multiple myeloma and anaplastic plasmacytoma,is a rare disease that aggressively progresses.It is reported to be ver...As a morphological sub-type of multiple myeloma(MM),anaplastic myeloma(AM),which includes anaplastic multiple myeloma and anaplastic plasmacytoma,is a rare disease that aggressively progresses.It is reported to be very resistant to chemotherapy and exhibits a poor prognosis.1 Although AM was.detected in 2.6%of patients in a large series of cases,there have only been some case reports since AM was first reported in 1983.31 Therefore,AM lacks detailed descriptions and strict definitions.To further analyze the clinical and pathological features of AM patients and to provide some suggestions for diagnosis and treatment,we retrospectively analyzed four AM patients who were admitted to the Affliated Hospital of Qingdao University.展开更多
基金supported by the Natural Science Foundation of Shandong Province(No.ZR2022MB122)"Qingchuang science and technology plan"project of colleges and Universities in Shandong Province(No.2020KJC005).
文摘Regulation of phase structure has been recognized as one of the most effective ways to fabricate self-healing polymers with high mechanical strength.The mechanical properties of the resultant polymers are certainly affected by the size of separated phase domain.However,the study on this aspect is absence,because it can hardly exclude the influence of variation in monomer proportion required for tuning the separated phase size.Here,we report the first study on tuning the phase size through reversible addition-fragmentation chain transfer(RAFT)polymerization without changing the proportion of monomers.As expected,the size of separated phase has been successfully mediated from 15 nm to 9 nm by tuning the molecular weight of the chain transfer agent.It is found that the mechanical strength and the self-healing efficiency of the resultant polymers increase simultaneously with the decrease of phase size.The study on the formation kinetics of hydrogen bonds reveals that the decrease of phase size can facilitate the re-bonding rate of hydrogen bonds,even if the migration of polymer chains is restricted.
基金The study was supported by grants from the National Natural Science Foundation of China(No.81400166)the Key Research and Development Program of Shandong Province(No.2018GSF118157).
文摘As a morphological sub-type of multiple myeloma(MM),anaplastic myeloma(AM),which includes anaplastic multiple myeloma and anaplastic plasmacytoma,is a rare disease that aggressively progresses.It is reported to be very resistant to chemotherapy and exhibits a poor prognosis.1 Although AM was.detected in 2.6%of patients in a large series of cases,there have only been some case reports since AM was first reported in 1983.31 Therefore,AM lacks detailed descriptions and strict definitions.To further analyze the clinical and pathological features of AM patients and to provide some suggestions for diagnosis and treatment,we retrospectively analyzed four AM patients who were admitted to the Affliated Hospital of Qingdao University.
