Relapsed primary extraskeletal osteosarcoma of liver:A case report and review of literature

BACKGROUND Extraskeletal osteosarcoma(ESOS)is a highly malignant osteosarcoma that occurs in extraskeletal tissues.It often affects the soft tissues of the limbs.ESOS is classified as primary or secondary.Here,we report a case of primary hepatic osteosarcoma in a 76-year-old male patient,which is very rare.CASE SUMMARY Here,we report a case of primary hepatic osteosarcoma in a 76-year-old male patient.The patient had a giant cystic-solid mass in the right hepatic lobe that was evident on ultrasound and computed tomography.Postoperative pathology and immunohistochemistry of the mass,which was surgically removed,suggested fibroblastic osteosarcoma.Hepatic osteosarcoma reoccurred 48 d after surgery,resulting in significant compression and narrowing of the hepatic segment of the inferior vena cava.Consequently,the patient underwent stent implantation in the inferior vena cava and transcatheter arterial chemoembolization.Unfortunately,the patient died of multiple organ failure postoperatively.CONCLUSION ESOS is a rare mesenchymal tumor with a short course and a high likelihood of metastasis and recurrence.The combination of surgical resection and chemotherapy may be the best treatment.

超声心动图、浅表高频超声及联合使用诊断肺动脉瓣狭窄患儿瓣膜数的价值

目的评价超声心动图联合浅表高频超声探测新生儿及小儿肺动脉瓣狭窄(PS)患儿肺动脉瓣瓣叶数目的效果。方法分别对新生儿及小儿PS患儿的肺动脉瓣进行超声心动图及浅表高频超声二维成像。结果超声心动图、浅表高频超声和超声心动图联合浅表高频超声对明确新生儿及小儿PS患儿肺动脉瓣数目的敏感性分别为81.25%、87.50%和93.75%,特异性分别为75.00%、84.62%和92.31%,准确性分别为73.33%、83.33%和90.00%,阳性预测值为72.22%、82.35%和88.24%,阴性预测值为75.00%、84.61%和92.31%。以手术结果为金标准,超声心动图、浅表高频超声和超声心动图联合浅表高频超声为结果值,分别绘制ROC曲线,曲线下面积分别为0.728、0.830和0.897。结论超声心动图联合浅表高频超声能获得比单用心脏探头更清晰的肺动脉瓣膜二维信息,可为新生儿及小儿PS的瓣膜数目做出更准确判断,从而能为临床提供更可靠的信息。