A new liquid crystalline polyacetylene containing a phenyl benzoate mesogen (5) is synthesized,whose mesomorphic properties are found to be easily 'tunab1e' by simple mechanical perturbation. Thepolymerization...A new liquid crystalline polyacetylene containing a phenyl benzoate mesogen (5) is synthesized,whose mesomorphic properties are found to be easily 'tunab1e' by simple mechanical perturbation. Thepolymerization of 10- [ 4 - (4' -methoxyphenoxycarbonyl )phenoxycarbonyl] - 1 -decyne (4 ) in itiated by theWCl_6-Ph_4Sn/dioxane complex yields polymer 5 with a M_w of 28400. The molecular structure of 5 ischaracterized by NMR, IR, and UV spectroscopy and its liquid crystalline behavior is investigated by DSC,POM, and XRD analysis. Upon mechanical perturbation, 5 exhibits unusual agitation-induced high-strengthdisclinations, shear-induced inversion walls, and solidification-induced banded textures. Such phenomenahave been observed in the main-chain liquid crystalline polymers with rigid backbones, but have seldom beenreported for the side-chain liquid crystalline polymers with flexible backbones, suggesting that the rigidpolyacetylene backbone of 5 plays a constructive role in inducing the novel molecular alignments.展开更多
Background Nearly 15%colorectal cancer(CRC)patients received ileostomy,while surgical site infection(SSI)is a common complication after ileostomy wound closure.Purse-string closure was reported to reduce SSI rate in i...Background Nearly 15%colorectal cancer(CRC)patients received ileostomy,while surgical site infection(SSI)is a common complication after ileostomy wound closure.Purse-string closure was reported to reduce SSI rate in ileostomy wound closure compared with conventional linear closure,but had never been systematically reported in CRC patients.The present study aimed to compare the short-term outcomes between purse-string and conventional closure in Chinese CRC patients.Patients and methods A total of 57 CRC patients underwent ileostomy wounds closure in the Second Affiliated Hospital of Zhejiang University during November,2015 and October,2017 were retrospectively reviewed.Twenty-nine received purse-string closure while the others received conventional closure.The short-term outcomes including SSI rate,scar length,pain score and hospital stay were reviewed and analyzed.Results There were no significant differences in the characteristics of the patients between two groups.The SSI rate was similar within two groups(10.3%vs 10.7%,p=1.000).The purse-string closure group had a significantly short scar length(1.66 cm vs 5.30 cm,p<0.0001),but had no difference in operation time,hospital stay and postoperative pain.Conclusion The present study did not find superiority of Purse-string closure in SSI rate control.It seemed only had a cosmetic effect according to its shorter scar length.展开更多
基金This project was in part supported by the Hong Kong Research Grants Council(HKUST597/95P&6149/97P)
文摘A new liquid crystalline polyacetylene containing a phenyl benzoate mesogen (5) is synthesized,whose mesomorphic properties are found to be easily 'tunab1e' by simple mechanical perturbation. Thepolymerization of 10- [ 4 - (4' -methoxyphenoxycarbonyl )phenoxycarbonyl] - 1 -decyne (4 ) in itiated by theWCl_6-Ph_4Sn/dioxane complex yields polymer 5 with a M_w of 28400. The molecular structure of 5 ischaracterized by NMR, IR, and UV spectroscopy and its liquid crystalline behavior is investigated by DSC,POM, and XRD analysis. Upon mechanical perturbation, 5 exhibits unusual agitation-induced high-strengthdisclinations, shear-induced inversion walls, and solidification-induced banded textures. Such phenomenahave been observed in the main-chain liquid crystalline polymers with rigid backbones, but have seldom beenreported for the side-chain liquid crystalline polymers with flexible backbones, suggesting that the rigidpolyacetylene backbone of 5 plays a constructive role in inducing the novel molecular alignments.
基金supported by the Huadong Medicine Joint Funds of the Zhejiang Provincial Natural Science Foundation of China under Grant No.LHDMY22C060002the National Natural Science Foundation of China(82103684,11932017,82172851)+1 种基金the Fundamental Research Funds for the Central Universities(No.226-2022-00009)the Natural Science Foundation of Zhejiang Province(LQ20H180014).
文摘Background Nearly 15%colorectal cancer(CRC)patients received ileostomy,while surgical site infection(SSI)is a common complication after ileostomy wound closure.Purse-string closure was reported to reduce SSI rate in ileostomy wound closure compared with conventional linear closure,but had never been systematically reported in CRC patients.The present study aimed to compare the short-term outcomes between purse-string and conventional closure in Chinese CRC patients.Patients and methods A total of 57 CRC patients underwent ileostomy wounds closure in the Second Affiliated Hospital of Zhejiang University during November,2015 and October,2017 were retrospectively reviewed.Twenty-nine received purse-string closure while the others received conventional closure.The short-term outcomes including SSI rate,scar length,pain score and hospital stay were reviewed and analyzed.Results There were no significant differences in the characteristics of the patients between two groups.The SSI rate was similar within two groups(10.3%vs 10.7%,p=1.000).The purse-string closure group had a significantly short scar length(1.66 cm vs 5.30 cm,p<0.0001),but had no difference in operation time,hospital stay and postoperative pain.Conclusion The present study did not find superiority of Purse-string closure in SSI rate control.It seemed only had a cosmetic effect according to its shorter scar length.
