BACKGROUND Laparoscopic partial nephrectomy has been widely used in renal cell carcinoma treatment.The efficacy of GreenLight laser on Laparoscopic partial nephrectomy is still unknown.AIM To present the first series ...BACKGROUND Laparoscopic partial nephrectomy has been widely used in renal cell carcinoma treatment.The efficacy of GreenLight laser on Laparoscopic partial nephrectomy is still unknown.AIM To present the first series of laparoscopic partial nephrectomy(LPN)by GreenLight laser enucleation without renal artery clamping.Due to the excellent coagulation and hemostatic properties of the laser,laser-assisted LPN(LLPN)makes it possible to perform a“zero ischemia”resection.METHODS Fifteen patients with T1a exogenous renal tumors who received high-power GreenLight laser non-ischemic LPN in our hospital were retrospectively analyzed.All clinical information,surgical and post-operative data,complications,pathological and functional outcomes were analyzed.RESULTS Surgery was successfully completed in all patients,and no open or radical nephrectomy was performed.The renal artery was not clamped,leading to no ischemic time.No blood transfusions were required,the average hemoglobin level ranged from 96.0 to 132.0 g/L and no postoperative complications occurred.The mean operation time was 104.3±8.2 min.The postoperative removal of negative pressure drainage time ranged from 5.0 to 7.0 d,and the mean postoperative hospital stay was 6.5±0.7 d.No serious complications occurred.Postoperative pathological results showed clear cell carcinoma in 12 patients,papillary renal cell carcinoma in 2 patients,and hamartoma in 1 patient.The mean creatinine level was 75.0±0.8μmol/L(range 61.0-90.4μmol/L)at 1 mo after surgery,and there were no statistically significant differences compared with pre-operation(P>0.05).The glomerular filtration rate ranged from 45.1 to 60.8 mL/min,with an average of 54.0±5.0 mL/min,and these levels were not significantly different from those before surgery(P>0.05).CONCLUSION GreenLight laser has extraordinary cutting and sealing advantages when used for small renal tumors(exogenous tumors of stage T1a)during LPN.However,use of this technique can lead to the generation of excessive smoke.展开更多
This paper deals with an in-line network security processor (NSP) design that implements the Internet Protocol Security (IPSec) protocol processing for the 10 Gbps Ethernet. The 10 Gbps high speed data transfer, the I...This paper deals with an in-line network security processor (NSP) design that implements the Internet Protocol Security (IPSec) protocol processing for the 10 Gbps Ethernet. The 10 Gbps high speed data transfer, the IPSec processing including the crypto-operation, the database query, and IPSec header processing are integrated in the design. The in-line NSP is implemented using 65 nm CMOS technology and the layout area is 2.5 mm×3 mm with 360 million gates. A configurable crossbar data transfer skeleton implementing an iSLIP scheduling algorithm is proposed, which enables simultaneous data transfer between the heterogeneous multiple cores. There are, in addition, a high speed input/output data buffering mechanism and design of high performance hardware structures for modules, wherein the transfer efficiency and the resource utilization are maximized and the IPSec protocol processing achieves 10 Gbps line speed. A high speed and low power hardware look-up method is proposed, which effectively reduces the area and power dissipation. The post simulation results demonstrate that the design gives a peak throughput for the Authentication Header (AH) transport mode of 10.06 Gbps with the average test packet length of 512 bytes under the clock rate of 250 MHz, and power dissipation less than 1 W is obtained. An FPGA prototype is constructed to verify the function of the design. A test bench is being set up for performance and function verification.展开更多
基金Supported by the Program of Shanghai Academic/Technology Research Leader,No.19XD1405100the Clinical Research Plan of SHDC,No.SHDC2020CR4025Hospital Funded Clinical Research,Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,No.21XHDB06.
文摘BACKGROUND Laparoscopic partial nephrectomy has been widely used in renal cell carcinoma treatment.The efficacy of GreenLight laser on Laparoscopic partial nephrectomy is still unknown.AIM To present the first series of laparoscopic partial nephrectomy(LPN)by GreenLight laser enucleation without renal artery clamping.Due to the excellent coagulation and hemostatic properties of the laser,laser-assisted LPN(LLPN)makes it possible to perform a“zero ischemia”resection.METHODS Fifteen patients with T1a exogenous renal tumors who received high-power GreenLight laser non-ischemic LPN in our hospital were retrospectively analyzed.All clinical information,surgical and post-operative data,complications,pathological and functional outcomes were analyzed.RESULTS Surgery was successfully completed in all patients,and no open or radical nephrectomy was performed.The renal artery was not clamped,leading to no ischemic time.No blood transfusions were required,the average hemoglobin level ranged from 96.0 to 132.0 g/L and no postoperative complications occurred.The mean operation time was 104.3±8.2 min.The postoperative removal of negative pressure drainage time ranged from 5.0 to 7.0 d,and the mean postoperative hospital stay was 6.5±0.7 d.No serious complications occurred.Postoperative pathological results showed clear cell carcinoma in 12 patients,papillary renal cell carcinoma in 2 patients,and hamartoma in 1 patient.The mean creatinine level was 75.0±0.8μmol/L(range 61.0-90.4μmol/L)at 1 mo after surgery,and there were no statistically significant differences compared with pre-operation(P>0.05).The glomerular filtration rate ranged from 45.1 to 60.8 mL/min,with an average of 54.0±5.0 mL/min,and these levels were not significantly different from those before surgery(P>0.05).CONCLUSION GreenLight laser has extraordinary cutting and sealing advantages when used for small renal tumors(exogenous tumors of stage T1a)during LPN.However,use of this technique can lead to the generation of excessive smoke.
基金Project supported by the Major Program of the Ministry of Industry and Information Technology of China(No.2017ZX01030301)the Beijing Natural Science Foundation of China(No.4162053)
基金Project (No. 2011ZX01034-002-002-003) supported by the National Science and Technology Major Projects of the Ministry of Industry and Information Technology, China
文摘This paper deals with an in-line network security processor (NSP) design that implements the Internet Protocol Security (IPSec) protocol processing for the 10 Gbps Ethernet. The 10 Gbps high speed data transfer, the IPSec processing including the crypto-operation, the database query, and IPSec header processing are integrated in the design. The in-line NSP is implemented using 65 nm CMOS technology and the layout area is 2.5 mm×3 mm with 360 million gates. A configurable crossbar data transfer skeleton implementing an iSLIP scheduling algorithm is proposed, which enables simultaneous data transfer between the heterogeneous multiple cores. There are, in addition, a high speed input/output data buffering mechanism and design of high performance hardware structures for modules, wherein the transfer efficiency and the resource utilization are maximized and the IPSec protocol processing achieves 10 Gbps line speed. A high speed and low power hardware look-up method is proposed, which effectively reduces the area and power dissipation. The post simulation results demonstrate that the design gives a peak throughput for the Authentication Header (AH) transport mode of 10.06 Gbps with the average test packet length of 512 bytes under the clock rate of 250 MHz, and power dissipation less than 1 W is obtained. An FPGA prototype is constructed to verify the function of the design. A test bench is being set up for performance and function verification.
