To analyse the genotypes of clinical isolates of Extended-Spectrum-β-Lactamase-Producing (ESBL-producing) Proteus mirabilis (P. mirabilis) and the mechanisms of antimicrobial resistance, to guide reasonable use of an...To analyse the genotypes of clinical isolates of Extended-Spectrum-β-Lactamase-Producing (ESBL-producing) Proteus mirabilis (P. mirabilis) and the mechanisms of antimicrobial resistance, to guide reasonable use of antibiotics and to avoid nosocomial outbreak infections by ESBL-producing P. mirabilis. 125 clinical isolates of P. mirabilis were collected from the Drug-Resistant Bacteria Surveillance Center of Anhui Province (from Jan 2009 to May 2010). Searching for the genotypes of ESBLs was perfomed by PCR amplification and DNA sequencing, and performed conjugation test simultaneously. Among ESBL-producing strains, CTX-M was the major genotype (3 CTX-M-13 and 1 CTX-M-3). TEM-1b spectrum β-lactamase was also prevalence in P. mirabilis. The diversity of β-lactamases in P. mirabilis and the emergency of multi-drug-resistance clinical strains will present serious threat to clinical therapy and even will lead to outbreak of nosocomial infections. Our study emphasizes the need for enhanced supervision of ESBL-producing P. mirabilis. Timely and reasonable drug-resistance data are indispensable to clinical therapy.展开更多
The ocean fishery is an important part of the marine economy and an important source of human food.The leaders at all levels attach great importance to the development and utilization of ocean fishery resources.Using ...The ocean fishery is an important part of the marine economy and an important source of human food.The leaders at all levels attach great importance to the development and utilization of ocean fishery resources.Using the regression analysis method,we forecast the main indicators for the development of ocean fishery during the Twelfth Five-Year Plan period.Through the study,it is found that in 2015,the value added of ocean fishery in China is expected to exceed 360 billion yuan,and the output of marine products will exceed 30 million tons.The marine products make stable contribution to the marine economy and the residents'nutrient composition,conducive to maintaining the stable supply of the market and meeting the residents'daily needs for marine products.展开更多
文摘To analyse the genotypes of clinical isolates of Extended-Spectrum-β-Lactamase-Producing (ESBL-producing) Proteus mirabilis (P. mirabilis) and the mechanisms of antimicrobial resistance, to guide reasonable use of antibiotics and to avoid nosocomial outbreak infections by ESBL-producing P. mirabilis. 125 clinical isolates of P. mirabilis were collected from the Drug-Resistant Bacteria Surveillance Center of Anhui Province (from Jan 2009 to May 2010). Searching for the genotypes of ESBLs was perfomed by PCR amplification and DNA sequencing, and performed conjugation test simultaneously. Among ESBL-producing strains, CTX-M was the major genotype (3 CTX-M-13 and 1 CTX-M-3). TEM-1b spectrum β-lactamase was also prevalence in P. mirabilis. The diversity of β-lactamases in P. mirabilis and the emergency of multi-drug-resistance clinical strains will present serious threat to clinical therapy and even will lead to outbreak of nosocomial infections. Our study emphasizes the need for enhanced supervision of ESBL-producing P. mirabilis. Timely and reasonable drug-resistance data are indispensable to clinical therapy.
文摘The ocean fishery is an important part of the marine economy and an important source of human food.The leaders at all levels attach great importance to the development and utilization of ocean fishery resources.Using the regression analysis method,we forecast the main indicators for the development of ocean fishery during the Twelfth Five-Year Plan period.Through the study,it is found that in 2015,the value added of ocean fishery in China is expected to exceed 360 billion yuan,and the output of marine products will exceed 30 million tons.The marine products make stable contribution to the marine economy and the residents'nutrient composition,conducive to maintaining the stable supply of the market and meeting the residents'daily needs for marine products.
