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A VOXEL BASED MICROCOMPUTER 3D RECONSTRUCTION SYSTEM
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作者 Chuanping Shi Li Yang +1 位作者 Guangming Li xianhua gao 《Chinese Journal of Biomedical Engineering(English Edition)》 1993年第4期159-159,共1页
In recent years,the volumetric approach of 3D reconstruction has emerged as apowerful clinic method for biomedical applications.This approach is based on a voxelrepresented object which maintains many details of the s... In recent years,the volumetric approach of 3D reconstruction has emerged as apowerful clinic method for biomedical applications.This approach is based on a voxelrepresented object which maintains many details of the surface and the internal con-structures of the original body.Because of a huge amount of data,the volume dataset takes a large size of memory,and a high processing speed is required in order… 展开更多
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家族性腺瘤性息肉病患者结直肠息肉的内镜下诊断治疗进展
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作者 刘宝帅 高显华 +3 位作者 潘受禹 曹强坚 刘连杰 张卫 《中华结直肠疾病电子杂志》 2024年第1期26-31,共6页
家族性腺瘤性息肉病(FAP)是一种以结直肠内多发性腺瘤性息肉为特征的遗传性综合征。广义上,所有的腺瘤性息肉病都可以称为FAP;狭义上,只有APC基因突变引起的腺瘤性息肉病才是FAP。FAP患者的结直肠内会出现数十枚甚至数千枚腺瘤性息肉,... 家族性腺瘤性息肉病(FAP)是一种以结直肠内多发性腺瘤性息肉为特征的遗传性综合征。广义上,所有的腺瘤性息肉病都可以称为FAP;狭义上,只有APC基因突变引起的腺瘤性息肉病才是FAP。FAP患者的结直肠内会出现数十枚甚至数千枚腺瘤性息肉,发生结直肠癌的风险非常高。预防性全大肠切除术(TPC)或全结肠切除术(TC)是FAP的标准治疗方案。近年来,内镜下治疗结直肠息肉取得了巨大的进步,不仅可以治愈轻表型FAP,还可用于经典型FAP,推迟手术的时机;FAP患者行TPC/TC术后也需要定期行结肠镜监测,以免残余直肠、回肠储袋和肛管移行区发生癌变。随着内镜检查和治疗方法的不断进步,内镜下息肉切除术治疗FAP的适应证在逐渐扩大,内镜下可切除的息肉数目越来越多;TPC/TC的时机被不断地推迟,可以保留直肠的FAP患者也越来越多。内镜下治疗有利于改善患者的排尿排便和性功能,提高生活质量;但需要反复进行,有出血、穿孔和癌变的风险,而且治疗费用高。其长期结果和成本效益还有待进一步评估。 展开更多
关键词 家族性腺瘤性息肉病 结肠息肉 直肠息肉 残余直肠 回肠储袋 内镜治疗
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幼年性息肉病的临床病理学特征及研究进展
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作者 何宗杰 白辰光 +1 位作者 高显华 张卫 《中华结直肠疾病电子杂志》 2024年第1期21-25,共5页
幼年性息肉病(JPS)是一种常染色体显性遗传的错构瘤性息肉综合征,以胃肠道出现多发幼年性息肉为主要表现,以结直肠息肉多见。JPS患者存在极高的胃肠道肿瘤发生风险,多数为结直肠癌,尽早检出尤为重要。JPS患者的幼年性息肉随疾病进展而... 幼年性息肉病(JPS)是一种常染色体显性遗传的错构瘤性息肉综合征,以胃肠道出现多发幼年性息肉为主要表现,以结直肠息肉多见。JPS患者存在极高的胃肠道肿瘤发生风险,多数为结直肠癌,尽早检出尤为重要。JPS患者的幼年性息肉随疾病进展而呈现多样性的病理组织学表现,甚至出现腺瘤或腺癌结构,基因检测有助于精准诊断。约60%的JPS患者存在SMAD4和BMPR1A基因的胚系突变,PTEN、ENG和FOCAD等基因改变在少数病例中也有发现。JPS的治疗一般采取息肉切除或脏器切除,近年来在药物治疗方面也有所进展。 展开更多
关键词 肠息肉病 幼年性息肉病 幼年性息肉 临床表现 组织病理学 分子遗传学
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Multi-stage Sensitivity Analysis of Distributed Energy Systems: A Variance-based Sobol Method 被引量:5
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作者 Shangshang Wei Yiguo Li +2 位作者 xianhua gao Kwang Y.Lee Li Sun 《Journal of Modern Power Systems and Clean Energy》 SCIE EI CSCD 2020年第5期895-905,共11页
In the face of the pressing environmental issues,the past decade witnessed the booming development of the distributed energy systems(DESs).A notable problem of DESs is the inevitable uncertainty that may make DESs dev... In the face of the pressing environmental issues,the past decade witnessed the booming development of the distributed energy systems(DESs).A notable problem of DESs is the inevitable uncertainty that may make DESs deviate significantly from the deterministically obtained expectations,in both aspects of optimal design and economic operation.It thus necessitates the sensitivity analysis to quantify the impacts of the massive parametric uncertainties.This paper aims to give a comprehensive quantification,and carries out a multi-stage sensitivity analysis on DESs from the perspectives of evaluation criteria,optimal design and economic operation.First,a mathematical model of a DES is developed to present the solutions to the three stages of the DES.Second,the Monte-Carlo simulation is carried out subject to the probabilistic distributions of the energy,technical and economic parameters.Based on the simulation results,the variance-based Sobol method is applied to calculate the individual importance,interactional importance and total importance of various parameters.The comparison of the multi-stage results shows that only a few parameters play critical roles while the uncertainty of most of the massive parameters has little impact on the system performance.In addition,the influence of parameter interactions in the optimal design stage are much stronger than that in the evaluation criteria and operation strategy stages. 展开更多
关键词 Sensitivity analysis UNCERTAINTY operation design OPTIMIZATION parameter characteristic distributed energy system(DES)
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