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Separation of chiral drugs with β-CD phosphate by capillary electrophoresis
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作者 Xue Qin REN1 xiao dan su1 +2 位作者 Al Jin HUANG1 Yi Liang SUN1 Zeng Pei SUNZ2 (1 Department of Chemistry, Peking University, Beijing 100871 2 National Institute for the Control of pharmaceutical and Biological Products, Beijing 100050) 《Chinese Chemical Letters》 SCIE CAS CSCD 2000年第2期153-156,共4页
β-Cyclodextrin phosphate (β-CD-phosphate) was used as a selector for separating chiral drugs by capillary electrophoresis (CE). A solution comprising of 120 mmol/L Britton Robinson buffer (BRB) containing 10 mmol/L ... β-Cyclodextrin phosphate (β-CD-phosphate) was used as a selector for separating chiral drugs by capillary electrophoresis (CE). A solution comprising of 120 mmol/L Britton Robinson buffer (BRB) containing 10 mmol/L 0-CD phosphate with the pH adjusted to 7.0 was used as the background electrolyte (BGE), and a small amount of analyte was injected (600v/1s). Triethylamine, diethylamine, triethanolamine, diethanolamine, Tris added as modifier were compared. Isoprenaline, methoxamine, oxprenolol, practolol were successfully resolved. 展开更多
关键词 Capillary electrophoresis chiral separation β-cyclodextrin-phosphate ISOPRENALINE METHOXAMINE oxprenolol practolol.
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