目的观察焦氏头针结合言语训练对脑卒中后失语症(post-stroke aphasia,PSA)患者语言功能康复的影响。方法将60例PSA患者随机分为治疗组(焦氏头针联合言语训练)及对照组(神经系统电刺激仪联合言语训练),每组30例,每周治疗6次,共治疗6周...目的观察焦氏头针结合言语训练对脑卒中后失语症(post-stroke aphasia,PSA)患者语言功能康复的影响。方法将60例PSA患者随机分为治疗组(焦氏头针联合言语训练)及对照组(神经系统电刺激仪联合言语训练),每组30例,每周治疗6次,共治疗6周。治疗前后分别采用汉语标准失语症检查(China rehabilitation research center aphasia examination,CRRCAE)量表评定语言功能,采用日常生活交流能力(communication abilities in daily living,CADL)量表评定交流能力,采用简易智力状态检查(mini-mental state examination,MMSE)量表评定认知功能,并通过波士顿诊断性失语症检查法(Boston diagnostic aphasia examination,BDAE)评价临床疗效。结果与治疗前比较,治疗后两组患者CRRCAE量表各领域评分均明显升高(P<0.05),CADL、MMSE评分也明显升高(P<0.05);治疗组治疗前后MMSE量表评分差值明显大于对照组(P<0.05),CRRCAE量表的听、说、朗读、抄写评分差值显著大于对照组(P<0.05)。结论焦氏头针结合言语训练的治疗方案能够提高PSA患者语言功能、日常生活交流能力以及认知功能,尤其在改善听、说、朗读及抄写方面疗效显著。展开更多
Pregnancy toxemia is a metabolic disorder of lipid and glucose. Recent investigations have found that angiopoietin-like protein 3 (ANGPTL3) can contribute to disorder of carbohydrate and lipid metabolism. The presen...Pregnancy toxemia is a metabolic disorder of lipid and glucose. Recent investigations have found that angiopoietin-like protein 3 (ANGPTL3) can contribute to disorder of carbohydrate and lipid metabolism. The present study was conducted to investigate the change of ANGPTL3 expression during pregnancy toxemia, We firstly cloned the full-length cDNA of ANGPTL3 in Liuyang Black goats, revealing that goat ANGPTL3 had the typical structure of the angiopoietin-like family, and its mRNA was exclusively expressed in liver. Pregnancy toxemia of pregnant goat does with twins during late gestation was induced by being fasted for 72 h, and then they were recovered after 5 d ofrefeeding. Hepatic ANGPTL3 gene expression was significantly down-regulated concomitantly with decreased serum glucose concentration, elevated serum β-hydroxybutyrate and free fatty acid levels in pregnant toxemic goats, and these changes were reversed after refeeding. These results suggest ANGPTL3 may play a certain role in the development of pregnancy toxemia in goats.展开更多
From 1985, an increasing gap has emerged between the official statistical measures of meat production and meat consumption in China, which has raised concerns from many researchers using such data. In this paper we re...From 1985, an increasing gap has emerged between the official statistical measures of meat production and meat consumption in China, which has raised concerns from many researchers using such data. In this paper we report the results of 428 observations(survey of 107 urban and rural households×4 quarters) from 7 provinces conducted in 2010, and compare them with the official statistical data from the National Bureau of Statistics of China(NBSC). We conclude that the main reason for the discrepancy is due to the underreporting of consumption, which is due mainly to the omission of consumption away from home.展开更多
Objective:To evaluate the clinical efficacy of the Governor Vessel-unblocking and mind-regulating acupuncture method plus repetitive transcranial magnetic stimulation(rTMS)in the treatment of post-stroke insomnia.Meth...Objective:To evaluate the clinical efficacy of the Governor Vessel-unblocking and mind-regulating acupuncture method plus repetitive transcranial magnetic stimulation(rTMS)in the treatment of post-stroke insomnia.Methods:A total of 72 patients with post-stroke insomnia were randomly divided into 2 groups,with 36 cases in each group.The control group received rTMS treatment with a frequency of 1 Hz and a motion threshold value of 90%.The observation group received acupuncture with Governor Vessel-unblocking and mind-regulating method based on the rTMS treatment of the control group.The points were Baihui(GV 20),Shenting(GV 24),Yintang(GV 29),Fengfu(GV 16),Sishencong(EX-HN I),Shenmen(HT I),Sanyinjiao(SP 6);Shenmai(BL 62)and Zhaohai(Kl 6).The treatment was performed once a day for 5 d a week followed by 2 d of rest for 4 weeks.The improvements of Pittsburgh sleep quality index(PSQI),self-rating anxiety scale(SAS)and self-rating depression scale(SDS)scores were observed after treatment,and the clinical efficacy was compared between the two groups.Results:After 4 weeks of treatment,the PSQI,SAS,and SDS scores of the two groups were all reduced,and the intra-group differences were statistically significant(all P<0.001).After treatment,the three scores in the observation group were all lower than those in the control group,and the differences between the two groups were statistically significant(P<0.05,P<0.05,P<0.001).There was a statistically significant difference between the observation group and the control group comparing the clinical efficacy(P<0.05).Conclusion:The therapeutic effect of the Governor Vessel-unblocking and mind-regulating acupuncture method plus rTMS in treating post-stroke insomnia is better than rTMS alone,and it can better improve the anxiety and depression of patients.展开更多
文摘目的观察焦氏头针结合言语训练对脑卒中后失语症(post-stroke aphasia,PSA)患者语言功能康复的影响。方法将60例PSA患者随机分为治疗组(焦氏头针联合言语训练)及对照组(神经系统电刺激仪联合言语训练),每组30例,每周治疗6次,共治疗6周。治疗前后分别采用汉语标准失语症检查(China rehabilitation research center aphasia examination,CRRCAE)量表评定语言功能,采用日常生活交流能力(communication abilities in daily living,CADL)量表评定交流能力,采用简易智力状态检查(mini-mental state examination,MMSE)量表评定认知功能,并通过波士顿诊断性失语症检查法(Boston diagnostic aphasia examination,BDAE)评价临床疗效。结果与治疗前比较,治疗后两组患者CRRCAE量表各领域评分均明显升高(P<0.05),CADL、MMSE评分也明显升高(P<0.05);治疗组治疗前后MMSE量表评分差值明显大于对照组(P<0.05),CRRCAE量表的听、说、朗读、抄写评分差值显著大于对照组(P<0.05)。结论焦氏头针结合言语训练的治疗方案能够提高PSA患者语言功能、日常生活交流能力以及认知功能,尤其在改善听、说、朗读及抄写方面疗效显著。
基金the National Natural Science Foundation of China (31072167)the Key Project of Hunan Provincial Science & Technology Department, China(2009FJ1005)Innovation Project of Hunan Provincial Education Department (CX2009B153), China
文摘Pregnancy toxemia is a metabolic disorder of lipid and glucose. Recent investigations have found that angiopoietin-like protein 3 (ANGPTL3) can contribute to disorder of carbohydrate and lipid metabolism. The present study was conducted to investigate the change of ANGPTL3 expression during pregnancy toxemia, We firstly cloned the full-length cDNA of ANGPTL3 in Liuyang Black goats, revealing that goat ANGPTL3 had the typical structure of the angiopoietin-like family, and its mRNA was exclusively expressed in liver. Pregnancy toxemia of pregnant goat does with twins during late gestation was induced by being fasted for 72 h, and then they were recovered after 5 d ofrefeeding. Hepatic ANGPTL3 gene expression was significantly down-regulated concomitantly with decreased serum glucose concentration, elevated serum β-hydroxybutyrate and free fatty acid levels in pregnant toxemic goats, and these changes were reversed after refeeding. These results suggest ANGPTL3 may play a certain role in the development of pregnancy toxemia in goats.
基金supported by the Earmarked Fund for Modern Agro-Industry Technology Research System,China(CARS-42-G24)the Agricultural Science and Technology Innovation Program,China(ASTIP-IAED-2015-01)+1 种基金the Project of Construction of Innovative Teams and Teacher Career Development for Universities and Colleges Under Beijing Municipality,China(IDHT20140510)the Project of Strategy of Ensuring China’s Animal Products Eatable Safety(13BGL098)
文摘From 1985, an increasing gap has emerged between the official statistical measures of meat production and meat consumption in China, which has raised concerns from many researchers using such data. In this paper we report the results of 428 observations(survey of 107 urban and rural households×4 quarters) from 7 provinces conducted in 2010, and compare them with the official statistical data from the National Bureau of Statistics of China(NBSC). We conclude that the main reason for the discrepancy is due to the underreporting of consumption, which is due mainly to the omission of consumption away from home.
文摘Objective:To evaluate the clinical efficacy of the Governor Vessel-unblocking and mind-regulating acupuncture method plus repetitive transcranial magnetic stimulation(rTMS)in the treatment of post-stroke insomnia.Methods:A total of 72 patients with post-stroke insomnia were randomly divided into 2 groups,with 36 cases in each group.The control group received rTMS treatment with a frequency of 1 Hz and a motion threshold value of 90%.The observation group received acupuncture with Governor Vessel-unblocking and mind-regulating method based on the rTMS treatment of the control group.The points were Baihui(GV 20),Shenting(GV 24),Yintang(GV 29),Fengfu(GV 16),Sishencong(EX-HN I),Shenmen(HT I),Sanyinjiao(SP 6);Shenmai(BL 62)and Zhaohai(Kl 6).The treatment was performed once a day for 5 d a week followed by 2 d of rest for 4 weeks.The improvements of Pittsburgh sleep quality index(PSQI),self-rating anxiety scale(SAS)and self-rating depression scale(SDS)scores were observed after treatment,and the clinical efficacy was compared between the two groups.Results:After 4 weeks of treatment,the PSQI,SAS,and SDS scores of the two groups were all reduced,and the intra-group differences were statistically significant(all P<0.001).After treatment,the three scores in the observation group were all lower than those in the control group,and the differences between the two groups were statistically significant(P<0.05,P<0.05,P<0.001).There was a statistically significant difference between the observation group and the control group comparing the clinical efficacy(P<0.05).Conclusion:The therapeutic effect of the Governor Vessel-unblocking and mind-regulating acupuncture method plus rTMS in treating post-stroke insomnia is better than rTMS alone,and it can better improve the anxiety and depression of patients.