The cross-correlation between the high-redshift 21 cm background and the Soft X-ray Background （SXB） of the Universe may provide an additional probe of the Epoch of Reionization. Here we use semi-numerical simulatio...The cross-correlation between the high-redshift 21 cm background and the Soft X-ray Background （SXB） of the Universe may provide an additional probe of the Epoch of Reionization. Here we use semi-numerical simulations to create 21 cm and soft X-ray intensity maps and construct their cross power spectra. Our results indicate that the cross power spectra are sensitive to the thermal and ionizing states of the intergalactic medium （IGM）. The 21 cm background correlates positively to the SXB on large scales during the early stages of the reionization. However as the reionization develops, these two back- grounds turn out to be anti-correlated with each other when more than - 15% of the IGM is ionized in a warm reionization scenario. The anti-correlated power reaches its maximum when the neutral fraction declines to 0.2-0.5. Hence, the trough in the cross power spectrum might be a useful tool for tracing the growth of HII regions during the middle and late stages of the reionization. We estimate the detectability of the cross power spectrum based on the abilities of the Square Kilometre Array and the Wide Field X-ray Telescope （WFXT）, and find that to detect the cross power spectrum, the pixel noise of X-ray images has to be at least 4 orders of magnitude lower than that of the WFXT deep survey.展开更多
Objective： To study the clinical characteristics, treatment, and prognosis of thyroid cancer in children and adolescents. Methods： We performed a retrospective analysis of clinical data from 83 cases of thyroid canc...Objective： To study the clinical characteristics, treatment, and prognosis of thyroid cancer in children and adolescents. Methods： We performed a retrospective analysis of clinical data from 83 cases of thyroid cancer in children and adolescents from January 1990 to December 2010. We compared extra-thyroid extension, lymph node metastasis, distant metastasis, and prognosis between pediatric patients 〈12 years of age （27 cases） and those 〉 12 years of age （56 cases）. All the patients agreed to undergo thyroidectomy and endocrine therapy, and the consent was obtained from parents or guardians. Results： Histopathology included papillary carcinoma in 67 cases, papillary carcinoma with partial follicular growth pattern in 1 case, papillary carcinoma with squamous metaplasia in 4 cases, follicular carcinoma in 7 cases, medullary carcinoma in 3 cases, and poorly differentiated carcinoma in 1 case. The total lymph node metastasis rate was 78.31%. Patients ≤12 years of age showed a higher rate of lymph node me- tastasis than the older group （92.59% vs. 71.43%, P=0.028）. The incidence rate in females in the older group was higher than that in the younger group （80.36% vs. 59.26%, P=0.041）. There were no significant differences in extra-thyroid extension, distant metastasis, survival rate, or recurrent disease between the two groups. Conclusions： The lymph node metastasis of thyroid cancer is higher in patients ≤12 years of age than in those 〉12 years of age; the incidence rate is higher in females than in males. Childhood thyroid cancer has a good prognosis, surgery being the most effective treatment. Choosing a reasonable surgery method and comprehensive postoperative treatment can achieve a cure and satisfactory survival rate.展开更多
基金supported by the National Natural Science Foundation of China(Grant Nos.11473031,11261140641 and 11173028)the 973 Program(Grant No.2013CB837900)
文摘The cross-correlation between the high-redshift 21 cm background and the Soft X-ray Background （SXB） of the Universe may provide an additional probe of the Epoch of Reionization. Here we use semi-numerical simulations to create 21 cm and soft X-ray intensity maps and construct their cross power spectra. Our results indicate that the cross power spectra are sensitive to the thermal and ionizing states of the intergalactic medium （IGM）. The 21 cm background correlates positively to the SXB on large scales during the early stages of the reionization. However as the reionization develops, these two back- grounds turn out to be anti-correlated with each other when more than - 15% of the IGM is ionized in a warm reionization scenario. The anti-correlated power reaches its maximum when the neutral fraction declines to 0.2-0.5. Hence, the trough in the cross power spectrum might be a useful tool for tracing the growth of HII regions during the middle and late stages of the reionization. We estimate the detectability of the cross power spectrum based on the abilities of the Square Kilometre Array and the Wide Field X-ray Telescope （WFXT）, and find that to detect the cross power spectrum, the pixel noise of X-ray images has to be at least 4 orders of magnitude lower than that of the WFXT deep survey.
文摘Objective： To study the clinical characteristics, treatment, and prognosis of thyroid cancer in children and adolescents. Methods： We performed a retrospective analysis of clinical data from 83 cases of thyroid cancer in children and adolescents from January 1990 to December 2010. We compared extra-thyroid extension, lymph node metastasis, distant metastasis, and prognosis between pediatric patients 〈12 years of age （27 cases） and those 〉 12 years of age （56 cases）. All the patients agreed to undergo thyroidectomy and endocrine therapy, and the consent was obtained from parents or guardians. Results： Histopathology included papillary carcinoma in 67 cases, papillary carcinoma with partial follicular growth pattern in 1 case, papillary carcinoma with squamous metaplasia in 4 cases, follicular carcinoma in 7 cases, medullary carcinoma in 3 cases, and poorly differentiated carcinoma in 1 case. The total lymph node metastasis rate was 78.31%. Patients ≤12 years of age showed a higher rate of lymph node me- tastasis than the older group （92.59% vs. 71.43%, P=0.028）. The incidence rate in females in the older group was higher than that in the younger group （80.36% vs. 59.26%, P=0.041）. There were no significant differences in extra-thyroid extension, distant metastasis, survival rate, or recurrent disease between the two groups. Conclusions： The lymph node metastasis of thyroid cancer is higher in patients ≤12 years of age than in those 〉12 years of age; the incidence rate is higher in females than in males. Childhood thyroid cancer has a good prognosis, surgery being the most effective treatment. Choosing a reasonable surgery method and comprehensive postoperative treatment can achieve a cure and satisfactory survival rate.
