AIM： TO analyze the factors influencing radical （R0） resection rate and surgical outcome for malignant tumor of the pancreatic body and tail. METHODS： The clinical and operative data and follow- up results of 214 ...AIM： TO analyze the factors influencing radical （R0） resection rate and surgical outcome for malignant tumor of the pancreatic body and tail. METHODS： The clinical and operative data and follow- up results of 214 pancreatic body and tail cancer patients were analyzed retrospectively. RESULTS： One hundred and twenty/214 pancreatic body and tail cancer patients underwent surgical treatment; the overall resection rate was 59.2% （71/120）, and the R0 resection rate was 40.8% （49/120）. Compared with non-R0 treatment, the patients receiving an R0 resection had smaller size tumor （P 〈 0.01）, cystadenocarcinoma （P 〈 0.01）, less lymph node metastasis （P 〈 0.01）, less peri-pancreatic organ involvement （P 〈 0.01） and earlier stage disease （P 〈 0.01）. The overall 1-, 3- and 5-year survival rates for pancreatic body and tail cancer patients were 12.7% （251197）, 7.6% （151197） and 2.5% （5/197）, respectively, and ductal adenocarcinoma patients had worse survival rates [15.0% （9/60）, 6.7% （4/60） and 1.7% （1/60）, respectively] than cystadenocarcinoma patients [53.8% （21139）, 28.2% （11139） and 10.3% （4139）] （P 〈 0.01）. Moreover, the 1-, 3- and 5-year overall survival rates in patients with RO resection were 55.3% （26/47）, 31.9% （15/47） and 10.6% （5/47）, respectively, significantly better than those in patients with palliative resection [9.5% （2/21）, 0 and 0] and in patients with bypass or laparotomy [1.2% （1/81）, 0 and 0] （P 〈 0.01）. CONCLUSION： Early diagnosis is crucial for increasing the radical resection rate, and radical resection plays an important role in improving survival for pancreatic body and tail cancer patients.展开更多
To the Editor:Pilomatrixoma is a benign tumor that arises from hair follicle matrix cells and has a low recurrence rate.[1]Dermatofibrosarcoma protuberans(DFSP)is a lowgrade,slowly growing fibroblastic sarcoma with a ...To the Editor:Pilomatrixoma is a benign tumor that arises from hair follicle matrix cells and has a low recurrence rate.[1]Dermatofibrosarcoma protuberans(DFSP)is a lowgrade,slowly growing fibroblastic sarcoma with a high local recurrence rate and a low propensity for metastasis.[2]We report a case that was clinically suspected to be DFSP,but the surgical biopsy confirmed a diagnosis of pilomatrixoma.A 29-year-old woman presented with a 1-year history of a localized asymptomatic mass on the posterior aspect of her neck[Figure 1A].The lesion had begun as a slowly growing,asymptomatic,bean-sized,reddish nodule.After external friction 6 months previously,the lesion had become a rapidly growing,painful,firm,reddish masswith ulceration and bleeding.After topical application of mupirocin ointment,the pain was relieved and the mass was slightly reduced in size.展开更多
文摘AIM： TO analyze the factors influencing radical （R0） resection rate and surgical outcome for malignant tumor of the pancreatic body and tail. METHODS： The clinical and operative data and follow- up results of 214 pancreatic body and tail cancer patients were analyzed retrospectively. RESULTS： One hundred and twenty/214 pancreatic body and tail cancer patients underwent surgical treatment; the overall resection rate was 59.2% （71/120）, and the R0 resection rate was 40.8% （49/120）. Compared with non-R0 treatment, the patients receiving an R0 resection had smaller size tumor （P 〈 0.01）, cystadenocarcinoma （P 〈 0.01）, less lymph node metastasis （P 〈 0.01）, less peri-pancreatic organ involvement （P 〈 0.01） and earlier stage disease （P 〈 0.01）. The overall 1-, 3- and 5-year survival rates for pancreatic body and tail cancer patients were 12.7% （251197）, 7.6% （151197） and 2.5% （5/197）, respectively, and ductal adenocarcinoma patients had worse survival rates [15.0% （9/60）, 6.7% （4/60） and 1.7% （1/60）, respectively] than cystadenocarcinoma patients [53.8% （21139）, 28.2% （11139） and 10.3% （4139）] （P 〈 0.01）. Moreover, the 1-, 3- and 5-year overall survival rates in patients with RO resection were 55.3% （26/47）, 31.9% （15/47） and 10.6% （5/47）, respectively, significantly better than those in patients with palliative resection [9.5% （2/21）, 0 and 0] and in patients with bypass or laparotomy [1.2% （1/81）, 0 and 0] （P 〈 0.01）. CONCLUSION： Early diagnosis is crucial for increasing the radical resection rate, and radical resection plays an important role in improving survival for pancreatic body and tail cancer patients.
基金the National Key Research and Development Program of China(No.2016YFC0901500)the Chinese Academy of Medical Sciences(CAMS)Initiative for Innovative Medicine(No.2017-I2M-B&R-01).
文摘To the Editor:Pilomatrixoma is a benign tumor that arises from hair follicle matrix cells and has a low recurrence rate.[1]Dermatofibrosarcoma protuberans(DFSP)is a lowgrade,slowly growing fibroblastic sarcoma with a high local recurrence rate and a low propensity for metastasis.[2]We report a case that was clinically suspected to be DFSP,but the surgical biopsy confirmed a diagnosis of pilomatrixoma.A 29-year-old woman presented with a 1-year history of a localized asymptomatic mass on the posterior aspect of her neck[Figure 1A].The lesion had begun as a slowly growing,asymptomatic,bean-sized,reddish nodule.After external friction 6 months previously,the lesion had become a rapidly growing,painful,firm,reddish masswith ulceration and bleeding.After topical application of mupirocin ointment,the pain was relieved and the mass was slightly reduced in size.
