Schizophrenia is a severe mental disorder characterized by impaired perception, delusions, thought disorder, abnormal emotion regulation, altered motor function, and impaired drive. The default mode network （DMN）, s...Schizophrenia is a severe mental disorder characterized by impaired perception, delusions, thought disorder, abnormal emotion regulation, altered motor function, and impaired drive. The default mode network （DMN）, since it was first proposed in 2001, has become a central research theme in neuropsychiatric disorders, including schizophrenia. In this review, first we define the DMN and describe its functional activity, functional and anatomical connectivity, heritability, and inverse correlation with the task positive network. Second, we review empirical studies of the anatomical and functional DMN, and anti-correlation between DMN and the task positive network in schizophrenia. Finally, we review preliminary evidence about the relationship between antipsychotic medications and regulation of the DMN, review the role of DMN as a treatment biomarker for this disease, and consider the DMN effects of individualized therapies for schizophrenia.展开更多
By considering the static voltage characteristic of the load, we propose a WAMS/SCADA mixed nonlinear method to estimate the voltage of unobservable buses caused by topology change or phasor measurement unit (PMU) mal...By considering the static voltage characteristic of the load, we propose a WAMS/SCADA mixed nonlinear method to estimate the voltage of unobservable buses caused by topology change or phasor measurement unit (PMU) malfunction in a power system. By modeling the load characteristic with data from SCADA, we employed the Gauss-Seidel method to solve the nonlinear equations and estimate the voltage of unobservable buses with the high precision voltages of neighboring buses measured by a PMU. Simulations were carried out on the IEEE 39-bus system, and the results show that this novel method can dynamically and accurately trace the variation of the voltage phasor of the unobservable buses.展开更多
基金supported by the National Natural Science Foundation of China(81271484,81471361,30900486,and 81371480)the National Basic Research Development Program(973 Program)of China(2012CB517904)the Nation Sponsored Study Abroad Program from China Scholarship Council(201506370095)
文摘Schizophrenia is a severe mental disorder characterized by impaired perception, delusions, thought disorder, abnormal emotion regulation, altered motor function, and impaired drive. The default mode network （DMN）, since it was first proposed in 2001, has become a central research theme in neuropsychiatric disorders, including schizophrenia. In this review, first we define the DMN and describe its functional activity, functional and anatomical connectivity, heritability, and inverse correlation with the task positive network. Second, we review empirical studies of the anatomical and functional DMN, and anti-correlation between DMN and the task positive network in schizophrenia. Finally, we review preliminary evidence about the relationship between antipsychotic medications and regulation of the DMN, review the role of DMN as a treatment biomarker for this disease, and consider the DMN effects of individualized therapies for schizophrenia.
基金Project supported by the National Natural Science Foundation of China (Nos. 50507018, 50595414, 50677062, and 60421002)the National Basic Research Program (973) of China (No. 2004CB217902)+1 种基金the National Key Technologies Supporting Program of Chinaduring the 11th Five-Year Plan Period (No. 2006BAA02A01)theKey Grant Project of MOE of China (No. 305008)
文摘By considering the static voltage characteristic of the load, we propose a WAMS/SCADA mixed nonlinear method to estimate the voltage of unobservable buses caused by topology change or phasor measurement unit (PMU) malfunction in a power system. By modeling the load characteristic with data from SCADA, we employed the Gauss-Seidel method to solve the nonlinear equations and estimate the voltage of unobservable buses with the high precision voltages of neighboring buses measured by a PMU. Simulations were carried out on the IEEE 39-bus system, and the results show that this novel method can dynamically and accurately trace the variation of the voltage phasor of the unobservable buses.
基金Project supported by the National Basic Research Program of China(No.2017YFA0206101)the National Defense Innovation Fund of Chinese Academy of Sciences(No.CXJJ-16M106)+1 种基金the "Strategic Priority Research Program" of the Chinese Academy of Sciences(No.XDA09020402)the Science and Technology Council of Shanghai,China(Nos.14DZ2294900,13ZR1447200,and 14ZR1447500)
