Introduction Psoriasis characterized by red scaly skin lesions clinically is a chronic inflammatory skin disease,and there are 0.53％-11.43％ of the adults around the world suffered[1].The pathophysiological changes o...Introduction Psoriasis characterized by red scaly skin lesions clinically is a chronic inflammatory skin disease,and there are 0.53％-11.43％ of the adults around the world suffered[1].The pathophysiological changes of psoriasis are characterized by proliferation accelerated in epidermal basal keratinocytes and infiltration of inflammatory cells from epidermis and dermis.Many studies have shown that the occurrence and development of psoriasis is closely related to genes,cell signaling pathways and proliferation.The relationships between peroxisome proliferator-activated receptor-γ(PPARγ) and TGF-β/Smad signaling pathway and psoriasis has been mostly studied in recent years[2].展开更多
基金National Natural Science Foundation of Jiangxi Provice of China (20122BAB205059)
文摘Introduction Psoriasis characterized by red scaly skin lesions clinically is a chronic inflammatory skin disease,and there are 0.53％-11.43％ of the adults around the world suffered[1].The pathophysiological changes of psoriasis are characterized by proliferation accelerated in epidermal basal keratinocytes and infiltration of inflammatory cells from epidermis and dermis.Many studies have shown that the occurrence and development of psoriasis is closely related to genes,cell signaling pathways and proliferation.The relationships between peroxisome proliferator-activated receptor-γ(PPARγ) and TGF-β/Smad signaling pathway and psoriasis has been mostly studied in recent years[2].
