The dynamic response and damage models of rebar reinforced polymer slabs subjected to contact and near-field explosions

Non aqueous reactive polymer materials produced by the reaction of isocyanate and polyol have been widely used in infrastructure construction,which may be subjected to explosion loads during complex service conditions.The blast response of composite materials is a crucial aspect for applications in engineering structures potentially subjected to extreme loadings.In this work,damage caused to rebar reinforced polymer slabs by surface explosive charges was studied experimentally and numerically.A total of 6 field tests were carried out to investigate the performances of the failure modes of rebar reinforced polymer slabs under contact and near-field explosions.The influence of explosive quantity(10-40 g)and stand-off distances(0-20 cm)at the damage modes were studied.The results show that the failure modes of rebar reinforced polymer slabs under near-field explosion mainly were bending and surface spalling,while under the impact of contact explosion,the failure modes were craters of the top surface,spalling of the bottom surface,and middle perforation.Furthermore,a detailed fully coupled model was developed and validated with the test data.The influences of explosive quantity and slab thickness on rebar reinforced polymer slabs under contact explosion were studied.Based on this,the calculation formula between breach diameter,explosive quantity,and slab thickness is fitted.

Photodynamic therapy for middle-advanced stage upper gastrointestinal carcinomas: A systematic review and meta-analysis

AIM To determine the therapeutic effect of photodynamic therapy(PDT) for middle-advanced stage upper gastrointestinal carcinomas. METHODS We searched PubM ed, EMBASE, the Cochrane Library, China National Knowledge Infrastructure, China Science and Technology Journal Database, and Wanfang Database from inception to April 2018 for randomized controlled studies. These studies compared PDT with other palliative therapies(radiotherapy, chemotherapy, or Nd:YAG laser) and compared PDT, radiotherapy, or chemotherapy alone with PDT combined with chemotherapy/radiotherapy. In our meta-analysis, both fixed and random effects models were used to estimate the risk ratio(RR) for dichotomous outcomes(the response rate and one-year survival rate).RESULTS Ten random controlled clinical studies with 953 patients were included in the analysis. The effective rate for PDT was better than that of radiotherapy or Nd:YAG laser for the treatment of middle-advanced upper gastrointestinal carcinomas [RR = 1.36; 95% confidence interval(CI): 1.13-1.65; P = 0.001]. In addition, PDT combined with chemotherapy had significantly better efficacy and a higher one-year survival rate than PDT or chemotherapy alone(significant remission rate, RR = 1.62; 95%CI: 1.34-1.97; P < 0.00001; one-year survival rate, RR = 1.81; 95%CI: 1.13-2.89; P = 0.01).CONCLUSION PDT is a useful method for the treatment of middleadvanced stage upper gastrointestinal carcinomas. PDT combined with chemotherapy or radiotherapy can enhance its efficacy and prolong survival time.

THE BULK INPUT M~[X]/M/1 QUEUE WITH WORKING VACATIONS

In this paper, we analyze a bulk input M^[X]/M/1 queue with multiple working vacations. A quasi upper triangle transition probability matrix of two-dimensional Markov chain in this model is obtained, and with the matrix analysis method, highly complicated probability generating function（PGF） of the stationary queue length is firstly derived, from which we got the stochastic decomposition result for the stationary queue length which indicates the evident relationship with that of the classical M^[X]/M/1 queue without vacation. It is important that we find the upper and the lower bounds of the stationary waiting time in the Laplace transform order using the properties of the conditional Erlang distribution. Furthermore, we gain the mean queue length and the upper and the lower bounds of the mean waiting time.