二硫代氨基甲酸盐络合分离钒铬及其在钒铬还原渣处理中的应用（英文）

提出一种从酸性溶液中分离回收钒和铬的新方法。该分离方法的原理基于选择性络合,五价钒可以与二硫代氨基甲酸盐络合反应生成VO(R1R2NCS2)3沉淀,三价铬则留在酸性溶液中;然后通过解络合从VO(R1R2NCS2)3沉淀中回收钒以及再生络合剂,通过中和水解法从三价铬溶液中回收铬。研究络合反应的动力学并计算其表观活化能。工艺优化后钒的沉淀率达到97%,铬损失小于4%,络合剂再生率可达99.5%。该分离方法已成功应用于常规钒生产工业产生的钒铬还原渣的处理,钒以钒酸钙的形式回收,铬以Cr2O3的形式回收,Cr2O3产品纯度超过98%。

含铝废LiFePO_(4)正极粉在H2SO_(4)溶液中的浸出性能

研究含铝废LiFePO_(4)(LFP)正极粉中LFP和Al的浸出行为及浸出动力学。考察温度(273~368 K)、搅拌速率(200~950 r/min)、反应时间(0~240 min)、酸料比(0.1:1~1:1 mL/g)和液固比(3:1~9:1 mL/g)对浸出过程的影响。结果表明,反应物浓度和温度对Al浸出影响较大。在优化的浸出条件下,LFP和Al的浸出率分别为91.53%和15.98%。动力学研究表明,LFP的浸出受表面化学反应与扩散混合控制,活化能为22.990 kJ/mol;而Al的浸出仅受表面化学反应的控制,活化能为46.581 kJ/mol。在废LFP正极材料酸浸过程中控制浸出体系低温能有效抑制铝的溶解。

Differential expression of microRNAs in aortic tissue and plasma in patients with acute aortic dissection

尖锐大动脉的解剖(AAD ) 的帮助 BackgroundBiomarker 的诊断为诊断和治疗是重要的。然而，为在血的 AAD 的 biomarkers 的鉴定是挑战性的任务 .&#x000a0；这研究的目的是寻找新潜在地，在 AAD.MethodsThe miRNAs 表示的 microRNA (miRNAs ) biomarkers 在登上大动脉的织物和血浆介绍被 microarray 分析在二个集合或组检验。织物组与 AAD 和健康男机关施主的四控制由四个病人组成。没有心血管的疾病，血浆组与 AAD 和 20 控制包括了 20 个病人。生物信息学被用来分析 miRNAs.ResultsOur 学习揭示了的表示的差别的潜在的目标在 AAD 病人，大动脉的织物有 30 差别，这表示了 miRNAs 与 13 起来调整并且 17 下面调整，并且血浆 93 差别表示了 miRNAs， 33 是起来调整的， 60 是下面调整的。四 miRNAs 被发现在 AAD 病人在大动脉的织物和血浆起来调整。预言的 miRNA 目标显示四 dysregulated miRNAs 主要指向了与房间房间粘附，细胞外的矩阵新陈代谢，细胞骨架组织，发炎，和与细胞的 cycles.ConclusionsFour miRNAs 有关的多重发信号小径被联系的基因，它在大动脉的织物并且在在 AAD 病人的血浆是起来调整的，在这研究被识别了。这些 miRNAs 可能是为 AAD 的潜在的诊断 biomarkers。更大的样品调查为进一步的确认被需要。

Effect of sigma phase precipitation on microstructure and properties of cast ZG0Cr26Ni5Mo3Cu3 duplex stainless steel under different heat treatments

ZG0Cr26Ni5Mo3Cu3 Duplex Stainless Steel(DSS) was solution treated at 1,060 ℃ for 3 h, followed by water cooling. Tempering treatments were conducted at 720, 750 and 780 ℃, respectively, for 16 h, followed by air cooling. The microstructures of ZG0Cr26Ni5Mo3Cu3 duplex stainless steel samples treated at different tempering temperatures were observed by scanning electron microscope(SEM) and energy dispersal spectroscopy(EDS), and the phase consitutions were analyzed using X-ray diffraction(XRD). The effects of the precipitation of sigma(σ) phase on the duplex phase percentage, hardness, impact toughness and corrosion resistance of the DSS were studied. Results showed that microstructures of ZG0Cr26Ni5Mo3Cu3 after solution treatment consists of ferrite(α) phase and austenite(γ) phase; after being tempered at different temperatures, σ phase appeared due to a eutectoid-type reaction of α→σ+γ2 during tempering treatment. It was observed that σ phase distributed along the grain boundary. The volume fraction of σ and γ phases increased with increasing tempering temperature in the range of 720 to 780 ℃, whereas the volume fraction of α phase showed the opposite trend. When the percentage of σ phase increased, the hardness of steel also increased. In the solution treated steel, hardness was measured to be only 244.0 HB, because σ phase did not appear. However, it increased to 391.8 HB when the DSS was tempered at 780℃because a great of deal of σ phase appeared. The impact toughness and corrosion resistance of DSS decreased when the percentage of σ phase increased.

Total knee arthroplasty in Ranawat Ⅱ valgus deformity with enlarged femoral valgus cut angle:A new technique to achieve balanced gap

BACKGROUND Nearly 10%of patients undergoing primary total knee arthroplasty(TKA)have valgus deformity(VD)of the knee.For severe VD of the knee,a more lateral structural release is needed to achieve balance between medial and lateral space and neutral femorotibial mechanical axis(FTMA),which is challenging and technical.AIM To introduce a new surgical technique of resection,soft tissue release,and FTMA for Ranawat type-Ⅱ VD with a 5-year follow-up.METHODS A retrospective study was conducted on patients who underwent TKA from December 2011 to December 2014.Hip-knee-ankle(HKA),range of motion(ROM),Oxford knee score(OKS),and knee society score(KSS)were used to assess the joint activity of patients in the new theory TKA group(NT-TKA)and were compared with those of the conventional TKA group(C-TKA).RESULTS A total of 103 people(103 knees)were included in this study,including 42 patients with an average follow-up period of 83 mo in the C-TKA group and 61 patients with an average follow-up period of 76 mo in the NT-TKA group.Six patients had constrained prosthesis,one had common peroneal nerve injury,and two had joint instability in the C-TKA group,but none of these occurred in the NT-TKA group.There were significant statistical differences in constrained prosthesis usage and complications between the groups(P=0.002 and P=0.034,respectively).The KSS at 1 mo post-operation for the C-TKA and NT-TKA groups were 11.2±3.8 and 13.3±2.9,respectively,with a significant difference(P=0.007).However,the data of HKA,ROM,OKS KSS,and prosthesis survival rate were insignificant(P>0.05)in both the preoperative and follow-up periods.CONCLUSION Adopting 5°-7°valgus cut angle for VD and sacrificing 2°neutral FTMA for severe VD which cannot be completely corrected during TKA can reduce the need for soft tissue release,maintain early joint stability,reduce the use of constrained prostheses,and minimize postoperative complications.

Ilioinguinal approach versus Stoppa approach for open reduction and internal fixation in the treatment of displaced acetabular fractures： A systematic review and meta-analysis

为了为代替的 acetabular 的治疗通过 ilioinguinal 途径和 Stoppa 途径比较开的减小和内部固定的功效和安全， 控制fractures.MethodsCase 的试用( CCT )从2010年1月出版了到在代替的 acetabular 破裂的管理比较了 ilioinguinal 途径和 Stoppa 途径的2015年8月从数据库被检索 Cochrane 图书馆， Pubmed ， CNKI 等等。试用的方法学的质量极其被估计。统计软件 RevMan 5.0 被用于数据 analysis.ResultsEight 文章在元分析被包括。通过在代替的 acetabular 骨折的治疗比较 ilioinguinal 途径和 Stoppa 途径的功效和安全，统计意义在平均操作时间被发现[ WMD ?=? 68.29 ，95% CI ( 10.52 ， 126.05 )， p ?<? 0.05 ]并且中部的 intraoperative 血损失[ WMD ?=? 142.26 ，95% CI ( 9.30 ， 275.23 )， p ?<? 0.05 ]。然而，在那里存在在破裂结束的统计意义都没重设满足率[ RR ?=? 0.63 ，95% CI ( 0.17 ， 2.37 )， p ?>? 0.05 ]，早复杂并发症评价[ RR ?=? 0.89 ，95% CI ( 0.33 ， 2.40 )， p ?>? 0.05 ]，迟了的复杂并发症评价[ RR ?=? 0.91 ，95% CI ( 0.27 ， 3.01 )， p ?>? 0.05 ]，并且哈里斯臀部 20 好功能率[ RR ?=? 0.52 ，95% CI ( 0.25 ， 1.10 )， p ?>? 0.05 ]两种技术能获得的 .ConclusionThough 在代替的 acetabular 破裂的处理的令人满意的临床的功能， Stoppa

Quadratus femoris muscle pedicle bone flap transplantation in the treatment of femoral neck fracture for Chinese young and middle-aged patients： A systematic review and meta-analysis

PurposeTo 比较骨头拍动移植在大腿骨的颈骨折的治疗与空压缩螺丝钉固定对 AO 空压缩螺丝钉固定相结合的 quadratus femoris 肌肉小花梗的功效因为中国年轻、中年的控制 patients.MethodsCase 的研究(CCT ) 被用来在大腿骨的颈破裂的治疗比较二个起作用的方法。数据从 Cochrane 图书馆被检索， Pubmed 数据库， CNKI，在 2005 年 1 月的经期期间出版到 2014 年 12 月的中国生物医学的 Database.Wanfang 数据。试用的方法学的质量极其被估计，并且相关数据被提取。统计软件 Revman 5.0 被用于 data-analysis.ResultsEight 文章在元分析被包括。结果证明处于骨折愈合的率有统计意义[或?=? 5.43 ，95% CI ( 2.89 ， 10.20 )， p ?<? 0.05 ]，新潮的关节的好功能的率[或?=? 5.12 ，95% CI ( 3.21 ， 8.17 )， p ?<? 0.05 ]，大腿骨的头坏死的率[或?=? 4.21 ，95% CI ( 2.02 ， 8.76 )， p ?<? 0.05 ]，骨折愈合的时间[ WMD ?=? 46.85 ，95% CI ( 65.13 ， 28.56 )， p ?<? 0.05 ]在二 groups.ConclusionsFor 之间，大腿骨的颈的治疗断裂， quadratus femoris 肌肉小花梗 bo 的移植固定以率比 AO 空压缩螺丝钉固定优异；骨折愈合，新潮的关节的好功能的率，大腿骨的头的率；坏死和骨折愈合的时间。

An efficient synthesis of substituted 1,4-diazepines by a Pd catalyzed amination and sequential hydrogenation condensation

代替的 1,4-diazepines 的有效合成被开发。可存取的中介经由催化 Pd 的胺化作用被获得了。没有特殊操作，随后的加氢和 intramolecular 冷凝作用序列能在一个壶连续地被进行。温和、一般的策略在高收益启用各种各样的代替的 1,4-diazepines 的合成。

Methylenetetrahydrofolate reductase C677T polymorphism predicts response and time to progression to gemcitabine-based chemotherapy for advanced non-small cell lung cancer in a Chinese Han population

Objective:The aim of this study was to evaluate the association between the methylenetetrahydrofolate reductase(MTHFR) C677T excision repair cross-complementation group 1(ERCC1) genetic polymorphisms and the clinical efficacy of gemcitabine-based chemotherapy in advanced non-small cell lung cancer(NSCLC).Methods:A total of 135 chemonaive patients with unresectable advanced NSCLC were treated with gemcitabine/platinum regimens.The polymorphisms of MTHFR C677T,ERCC1 C8092A,and ERCC1 C118T were genotyped using the TaqMan methods.Results:The overall response rate was 28.9%.Patients with MTHFR CC genotype had a higher rate of objective response than patients with variant genotype(TT or CT)(41.2% versus 19.1%,P=0.01).Median time to progression(TTP) of patients with MTHFR CC genotype was longer than that of patients with variant genotype(7.6 months versus 5.0 months,P=0.003).No significant associations were obtained between ERCC1 C118T and C8092A polymorphisms and both response and survival.Conclusions:Our data suggest the value of MTHFR C677T polymorphism as a possible predictive marker of response and TTP in advanced NSCLC patients treated with gemcitabine/platinum.

Morphology-controlled growth of large-area PtSe_(2) films for enhanced hydrogen evolution reaction

Transition metal dichalcogenides(TMDs)have emerged as a promising electrocatalyst for hydrogen evo-lution reaction(HER)due to its excellent conductivity and abundant electrocatalytic active sites of its edges.TMDs nanowall can expose abundant of edges so that they tend to show better catalytic performance for hydrogen evolution reaction.Herein,PtSe_(2) nanowall films with morphology controlled at centimeters level are synthesized by selenizing Pt film.The dynamic and thermodynamics of selenation reaction are investigated.The nanowall structure can be obtained by controlling the growth temperature,and the thickness of nanowall can be tuned by the original thickness of Pt film.The Pt atoms can be rearranged into ordered distribution at 550℃ and can be induced to well-ordered PtSe_(2) nanowalls finally.The well-ordered PtSe_(2) nanowall films show excellent HER performance,with an overpotential of 0.3 V at-10 mA·cm^(-2) and a Tafel slope of~52 mV·dec^(-1).This work demonstrates the great potential of activated 2D PtSe_(2) as an ultrathin film catalyst for the HER,which is valuable to provide instruction and afford experience for further application at industrial level.

An efficient method for preparing the sphingosine-1-phosphate receptor agonist, KRP203-phosphate

An efficient method for mono-phosphorylation of 2 （KRP203） using cbz-protection, dibenzylphosphoryl chloride and TMSI affording 2-P （KRP203-P） was developed. We applied the present method to the synthesis of KRP203 phosphate analogs which were difficult to produce through tradition procedures.

One pot synthesis of dibenzodiazepinones via CuI catalysis in ethylene glycol

A one pot protocol for the synthesis of dibenzodiazepinones was developed. The substituted ethyl 2- halobenzoates are cross-coupled with o-phenylenediamine utilizing a ligand-free, Cul catalyzed system, which spontaneously undergo an intramolecular N-acylation in ethylene glycol to give the corresponding products in high yields. This synthetic protocol provides a concise and efficient access to a wide variety of dibenzodiazepinone, including biologically active molecules.