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Mapping the intellectual structure and emerging trends for the application of nanomaterials in gastric cancer:A bibliometric study
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作者 Bo-Na Liu xiao-li gao Ying Piao 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第5期2181-2199,共19页
BACKGROUND Recent reviews have outlined the main nanomaterials used in relation to gastrointestinal tumors and described the basic properties of these materials.However,the research hotspots and trends in the applicat... BACKGROUND Recent reviews have outlined the main nanomaterials used in relation to gastrointestinal tumors and described the basic properties of these materials.However,the research hotspots and trends in the application of nanomaterials in gastric cancer(GC)remain obscure.AIM To demonstrate the knowledge structure and evolutionary trends of research into the application of nanomaterials in GC.METHODS Publications related to the application of nanomaterials in GC were retrieved from the Web of Science Core Collection for this systematic review and bibliometric study.VOSviewer and CiteSpace were used for bibliometric and visualization analyses.RESULTS From 2000 to 2022,the application of nanomaterials in GC developed rapidly.The keyword co-occurrence analysis showed that the related research topics were divided into three clusters:(1)The application of nanomaterials in GC treatment;(2)The application and toxicity of nanomaterials in GC diagnosis;and(3)The effects of nanomaterials on the biological behavior of GC cells.Complexes,silver nanoparticles,and green synthesis are the latest high-frequency keywords that represent promising future research directions.CONCLUSION The application of nanomaterials in GC diagnosis and treatment and the mechanisms of their effects on GC cells have been major themes in this field over the past 23 years. 展开更多
关键词 NANOMATERIALS Gastric cancer BIBLIOMETRICS Drug delivery VOSviewer CiteSpace Systematic review
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慢性乙型肝炎患者HBV-DNA载量与血清microRNA-122、ALT的相关性研究 被引量:8
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作者 杜波 高小丽 白雪梅 《中国现代医学杂志》 CAS 2020年第24期86-90,共5页
目的探讨慢性乙型肝炎(CHB)患者HBV-DNA载量与血清microRNA-122(miR-122)、丙氨酸转氨酶(ALT)的相关性,为进一步指导CBH患者的临床诊治提供科学依据。方法回顾性分析2017年1月-2019年3月榆林市中医医院收治的200例CHB患者作为研究对象... 目的探讨慢性乙型肝炎(CHB)患者HBV-DNA载量与血清microRNA-122(miR-122)、丙氨酸转氨酶(ALT)的相关性,为进一步指导CBH患者的临床诊治提供科学依据。方法回顾性分析2017年1月-2019年3月榆林市中医医院收治的200例CHB患者作为研究对象。采用RT-PCR法检测miR-122和HBV-DNA载量,采用肝功能检测试剂盒检测血清ALT含量,采用双抗体夹心法检测血清乙型肝炎e抗原(HBeAg)、乙型肝炎表面抗原(HBsAg),ELISA竞争法检测血清乙型肝炎e抗体(HBeAb)、乙型肝炎核心抗体(HBcAb)和乙型肝炎表面抗体(HBsAb)。分析慢性乙型肝炎HBV-DNA载量与血清miR-122、ALT含量的关系。结果模式1、2和3的患者HBV-DNA载量较模式4患者高(P<0.05),模式1的患者血清ALT含量较其他模式患者高(P<0.05)。低病毒载量组患者血清ALT阳性率最低(P<0.05)。超高病毒载量组患者miR-122相对表达量较其他载量组患者高(P<0.05)。经Pearson相关性分析,HBVDNA载量与ALT和miR-122均呈正相关(r=1.024和0.946,P<0.05)。结论CHB患者血清HBV-DNA载量与血清miR-122、ALT均呈正相关,三者联合检测可以相互补充,提高诊断的准确性,为临床诊治CHB患者提供更科学的依据。 展开更多
关键词 肝炎 乙型 慢性 HBV-DNA/核糖核酸酶类 丙氨酸转氨酶
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Water requirement pattern for tobacco and its response to water deficit in Guizhou Province 被引量:1
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作者 Shi-zhang Peng xiao-li gao +2 位作者 Shi-hong Yang Jing Yang He-xi Zhang 《Water Science and Engineering》 EI CAS CSCD 2015年第2期96-101,共6页
The water requirement pattern for tobacco(Yun 85) was identified based on analysis of data obtained from pot experiments in a canopy at the Xiuwen Irrigation Test Central Station in Guizhou Province, China. The resu... The water requirement pattern for tobacco(Yun 85) was identified based on analysis of data obtained from pot experiments in a canopy at the Xiuwen Irrigation Test Central Station in Guizhou Province, China. The results showed that the tobacco water requirement and the tobacco water requirement intensity throughout the growth period in pot experiments were significantly lower than those in field production. In pot experiments, the tobacco water requirement throughout the growth period ranged from 159.00 to 278.90 mm, with a reduction in the range of241e441 mm, as compared with that in field production. Also, the average water requirement intensity at the vigorous growing stage was1.97 mm/d, and the water requirement and water requirement module were 33.80e72.60 mm and 16.39%e33.09%, respectively, at the group stage, almost equal to their values at the vigorous growing stage. The patterns of the tobacco water requirement and water requirement module in pot experiments were different from those in field production. In pot experiments, the tobacco water requirement and water requirement module ranked the highest at the mature stage, followed by those at the group/vigorous growing and rejuvenation stages, while the water requirement intensity ranked the highest at the vigorous growing stage, followed by those at the mature, group, and rejuvenation stages. The pattern of the water requirement intensity in pot experiments was consistent with that in field production. In addition, the response of the tobacco water requirement to water deficit was also analyzed. Serious water deficit at the vigorous growing stage and continuous water stress at the group,vigorous growing, and mature stages can greatly influence the tobacco water requirement. Water deficit led to reductions in the water requirement and water requirement intensity at each growth stage. The vigorous growing stage exhibited the highest sensitivity to water deficit.The lower limit of moderate soil water stress at the vigorous growing stage was 65% of the field capacity. Results of this study can help to establish a reasonable irrigation schedule for tobacco production in Guizhou Province, China. 展开更多
关键词 Water requirement Protected cultivation Water deficit Tobacco Guizhou Province
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