Hepatocellular carcinoma(HCC)is a major health problem worldwide with high incidence and mortality rate[1,2].Proper treatments for HCC mainly include surgical resection,transcatheter arterial chemoembolization(TACE),r...Hepatocellular carcinoma(HCC)is a major health problem worldwide with high incidence and mortality rate[1,2].Proper treatments for HCC mainly include surgical resection,transcatheter arterial chemoembolization(TACE),radiofrequency ablation(RFA),and liver transplantation.However,many patients who are diagnosed with advanced HCC are not eligible for surgery,even the TACE and RFA does not necessarily have a good therapeutic effect.Until now,sorafenib is currently the first-line antitumor drug for the treatment of patients with advanced HCC.展开更多
基金supported by grants from the National Natural Science Foundation of China(81874228)Science and Tech-nology Department of Zhejiang Province(2015C03034)。
文摘Hepatocellular carcinoma(HCC)is a major health problem worldwide with high incidence and mortality rate[1,2].Proper treatments for HCC mainly include surgical resection,transcatheter arterial chemoembolization(TACE),radiofrequency ablation(RFA),and liver transplantation.However,many patients who are diagnosed with advanced HCC are not eligible for surgery,even the TACE and RFA does not necessarily have a good therapeutic effect.Until now,sorafenib is currently the first-line antitumor drug for the treatment of patients with advanced HCC.