Objective:To investigate whether sham feeding before colonoscopy can effect gastrointestinal hormone and compliance of colonoscopy patients when taking polyethylene glycol solution,so as to provide reference for effec...Objective:To investigate whether sham feeding before colonoscopy can effect gastrointestinal hormone and compliance of colonoscopy patients when taking polyethylene glycol solution,so as to provide reference for effective intervention programs.Methods:A total of 110 patients undergoing colonoscopy were randomized into a control group and an sham feeding group,with 55 patients in each group.Patients in control group only received polyethylene glycol(PEG)solution before colonoscopy.Patients in gum group chewed gum after taking PEG solution.Serum motilin,gastrin and cholecystokinin were tested with ELISA assay.Intestinal tract cleanliness was assessed by the Boston Bowel Preparation Scale and patients'discomfort and intake compliance by a self-designed questionnaire.Results:The serum motilin of sham feeding for 4 h were lower than that of control group,the incidence of abdominal distention and nausea in sham feeding group was lower than that in control group,and the intake compliance and the speed of peristalsis was better,but there was no statistical significance found in the total score of intestinal tract cleanliness,difficulty and time of endoscopic operation.There was no statistical significance between the two groups regarding cecal intubation rate and colonoscopic findings.Conclusions:patients with gum chewing increase serum motilin and accelerating speed of peristalsis,it can not enhances colonoscopy bowel preparation quality,but improved abdominal discomfort,and intake adherence of patients in colonoscopy preparation.展开更多
基金Hainan Provincial Science and Technology Department(KJHZ2015-19).
文摘Objective:To investigate whether sham feeding before colonoscopy can effect gastrointestinal hormone and compliance of colonoscopy patients when taking polyethylene glycol solution,so as to provide reference for effective intervention programs.Methods:A total of 110 patients undergoing colonoscopy were randomized into a control group and an sham feeding group,with 55 patients in each group.Patients in control group only received polyethylene glycol(PEG)solution before colonoscopy.Patients in gum group chewed gum after taking PEG solution.Serum motilin,gastrin and cholecystokinin were tested with ELISA assay.Intestinal tract cleanliness was assessed by the Boston Bowel Preparation Scale and patients'discomfort and intake compliance by a self-designed questionnaire.Results:The serum motilin of sham feeding for 4 h were lower than that of control group,the incidence of abdominal distention and nausea in sham feeding group was lower than that in control group,and the intake compliance and the speed of peristalsis was better,but there was no statistical significance found in the total score of intestinal tract cleanliness,difficulty and time of endoscopic operation.There was no statistical significance between the two groups regarding cecal intubation rate and colonoscopic findings.Conclusions:patients with gum chewing increase serum motilin and accelerating speed of peristalsis,it can not enhances colonoscopy bowel preparation quality,but improved abdominal discomfort,and intake adherence of patients in colonoscopy preparation.
