Clinical Analysis of 16 Cases with Duplex Uterus

Objective To explore the diagnosis and treatment of duplex uterus. Methods Totally 16 cases with duplex uterus were diagnosed and treated with hysteroscopy and laparoscopic technology simultaneously. Results Sixteen cases were finally diagnosed with hysteroscopy and B-ultrasound examination. Of the 16 cases, 12 cases underwent vaginal septum resection and hysteroscopic transcervical resection of septum （TCRS）, 2 cases underwent lysis of pelvic adhesions, vaginal septum resection and hysteroscopic transcervical resection of septum, and 2 unmarried cases underwent hysteroscopy in women with intact-hymen. All the 16 cases underwent the surgery successfully. Conclusion Hysteroscopy in combination with B-ultrasound examination is a major option for duplex uterus diagnosis, and hysteroscopic transcervical resection of septum and vaginal septum resection under B-ultrasound monitoring is the primary surgery treatment alternative for duplex uterus.

Anti-proliferative Properties of Schinensilactone A,A Schinortriterpenoid with 7,8-Seco-1,8-cyclo Scaffold against Caco-2 by Inducing Cell Apoptosis from the Leaves of Schisandra chinensis

A novel schinortriterpenoid(SNT),schinensilactone A(1),characterized by a unique 7,8-seco-1,8-cyclo-schisanartane scaffold,was isolated from the leaves of Schisandra chinensis(Turcz.)Baill,together with a new SNT(schinensilactone B,2)and two known(3,4).Their structures were elucidated using spectroscopy and X-ray diffraction.Furthermore,a hypothetical biosynthetic pathway for 1 was postulated due to its novel carbon skeleton.In addition,1 exhibited significant anti-proliferative activity against Caco-2 cells originat-ing from five different tumor cell lines,and its preliminary mechanism of action was investigated with respect to the expression of apoptosis-related proteins,including P53,Caspase 3,Bax,PUMA,and Bcl2.These biological activities would further our understanding of the food function of Schisandra chinensis leaves.