Effect of Glycyrrhiza uralensis Fisch polysaccharide on growth performance and immunologic function in mice in Ural City,Xinjiang

Objective:To discuss the effect of Glycyrrhiza uralensis(G.uralensis) Fisch polysaccharide on growth performance and immunologic function in mice in Ural City,Xinjiang and to provide important data supporting the application of Glycyrrhiza polysaccharide.Methods:A total of100 Kunming mice aged 3 weeks old were randomly divided into 5 groups with 20 mice in each group(10 were females and 10 were males).About 0.5 mL normal saline was given to the mice of control group every day and 0.5 mL G.uralensis Fisch polysaccharide was given to the mice of other groups at the concentration of 1,20,50 and 100 mg/mL respectively.The growth performance(average body weight,average daily feed intake and feed efficiency),immune organ indexes(spleen index and thymus index) and immunologic function(serum IL-2,CD4^+/CD8^+ and the activity of NK cells) of mice in each group were detected continuously.Results:The average body weight,feed efficiency,serum IL-2,CD4^+/CD8^+ and the activity of NK cells of mice were increased with the increase of administrated time after administrating G.uralensis Fisch polysaccharide and were reached up the largest level on Day 28.At the same time,each index was proportional to the given dose and was significantly higher than those of control group and reached up the largest level at the administrated dose of 100 mg/mL.After administrating G.uralensis Fisch polysaccharide,the spleen index and thymus index of mice were increased with the increase of administrated dose and the spleen index and thymus index of mice administrated with the dose of 100 mg/mL were maximum which was more than 1.51 times and 1.43 times of that in control group respectively and the comparative differences showed statistical significance(P<0.05).The average daily feed intake of mice in each group was increased with the passage of lime and at the same time,the comparison of average daily feed intake of mice in each group was not significantly different(P>0.05).Conclusions:G.uralensis Fisch polysaccharide can significantly improve the growth performance and immunologic function of mice and laid a research basis for the clinical application of G.uralensis Fisch polysaccharide.

Discovery of the Mid-Late Jurassic volcanic rocks(163.4 Ma) in Nanhuangcheng Island, Shandong Province, China

1.Objectives Changshan Islands are located on the geographical boundary between the Bohai Sea and the North Yellow Sea,China.Intensively tectonic deformation developed in this area,which is an important connection point to study the tectonics of the Shandong Peninsula and Liaoning Peninsula.Previous studies have shown that the lithologies of the three northern islands(Beihuangcheng Island,Nanhuangcheng Island,and Xiaoqin Island)of the Changshan Islands include Neoproterozoic quartzite,phyllite,and slate(Fuzikuang Formation of the Penglai Group),and a few areas are covered by Quaternary slope deposits,marine deposits and loess(Fig.1 a;Qiao EW et al.,2019).Recently,a set of volcanic rocks was firstly discovered in Nanhuangcheng Island(Fig.1 a).

Wind suitability in site analysis of coastal concave terrains using computational fluid dynamics simulation： a case study in East Asia

The effect of wind environment is becoming increasingly important in analyzing and selecting sites for better naturalventilation of residential buildings, external comfort, and pollution dispersion. The mainpurpose of this study was to develop a setof methods for wind environment assessment in coastal concave terrains. This set of methods can be used to provide quantifiableindicators of preferable wind conditions and help site analysis. Firstly, a total of 20 types of coastal bays with concave terrains inEast Asia were characterized to find ideal locations. The selected areas were divided into five categories according to the mainterrain features. Then a sample database for the concave terrains was compiled for modelling comparisons. Secondly, a number ofkey wind variables were identified. Computational fluid dynamics （CFD） models of the typical coastal concave terrains identifiedas a result of the study were created, and the local wind environments were simulated with input from geographic informationsystem （GIS） and statistic package for social science （SPSS） analysis. A measure of wind suitability was proposed that takes windvelocity and wind direction into account using GIS. Finally, SPSS was used to find the relationship between wind suitability andkey terrain factors. The results showed that wind suitability was significantly associated with terrain factors, especially altitude.The results suggest that residential building sites should be selected such that their bay openings face the direction of the prevailingwind and that the opposite direction should be avoided.