Numerical study on the dynamic fracture of explosively driven cylindrical shells

Research on the expansion and fracture of explosively driven metal shells has been a key issue in weapon development and structural protection.It is important to study and predict the failure mode,fracture mechanism,and fragment distribution characteristics of explosively driven metal shells.In this study,we used the finite element-smoothed particle hydrodynamics(FE-SPH)adaptive method and the fluid-structure interaction method to perform a three-dimensional numerical simulation of the expansion and fracture of a metal cylindrical shell.Our method combined the advantages of the FEM and SPH,avoiding system mass loss,energy loss,and element distortion;in addition,the proposed method had a good simulation effect on the interaction between detonation waves and the cylindrical shell.The simulated detonation wave propagation,shell damage morphology,and fragment velocity distribution were in good agreement with theoretical and experimental results.We divided the fragments into three regions based on their shape characteristics.We analyzed the failure mode and formation process of fragments in different regions.The numerical results reproduced the phenomenon in which cracks initiated from the inner surface and extended to the outer surface of the cylindrical shell along the 45°or 135°shear direction.In addition,fragments composed of elements are identified,and the mass and characteristic lengths of typical fragments at a stable time are provided.Furthermore,the mass and size distribution characteristics of the fragments were explored,and the variation in the fitting results of the classical distribution function under different explosion pressures was examined.Finally,based on mathematical derivation,the distribution formula of fragment velocity was improved.The improved formula provided higher accuracy and could be used to analyze any metal cylindrical shells with different length-to-diameter ratios.

Misdiagnosis of scalp angiosarcoma: A case report

BACKGROUND Angiosarcoma is a rare malignant tumor.Owing to the lack of specific clinical manifestations of this disease,it is difficult to achieve early diagnosis and start early treatment.CASE SUMMARY A 78-year-old male patient was admitted to the hospital because of a bump on his head that did not heal for 4 mo.The patient was diagnosed with a refractory head wound.The patient underwent neoplasm resection and skin grafting surgery in the Plastic Surgery.The neoplasm was sent for pathological examination during the operation.The final pathological results were confirmed scalp angiosarcoma.CONCLUSION Our research suggests that pathological examination should be performed for refractory ulcers of the scalp,and physical factor therapy should be used with caution before the diagnosis is clear.

Modeling on the shock wave in spheres hypervelocity impact on flat plates

In hypervelocity impacts of projectiles into thin flat targets,shock initiation and interaction dominate the responses of projectiles and targets,and especially dominate the features of the debris cloud.To estimate the geometric features of the wave front during the first complete propagation in the sphericalprojectile,the Geometric Propagation Model(GPM)is built in this paper to describe the geometry of the shock wave front,which proposes an ellipse contour as a function of time and equivalent speed.The GPM identifies the geometric features of the wave front as a function of time and impact velocity successfully.Combined with the GPM and SPH simulation,the shock pressure distribution and attenuation in the spherical-projectile have been obtained.Meanwhile,the attenuation of shock pressure and speed are presented as a function of impact velocity,respectively,and a method for obtaining the equivalent speed of the shock wave is proposed by the GPM.The GPM may be applicable to hypervelocity events involving any monolithic materials as long as the equivalent speed could be supplied from numerical simulation.The GPM proposed in this paper and the corresponding shock wave analysis provide a new insight into the processes of the quantitative analysis of the initiation of the debris cloud.

Damage assessment of the target area of the island/reef under the attack of missile warhead

Under the background of vigorously developing facilities of island/reef in the world,the economic value and strategic significance of the island/reef have become increasingly important.Unfortunately,they may easily become the attacking target of missiles in the war time.Therefore,aiming at the damage quantification of the targets in the island/reef under the missile attacking,a macroscopic damage assessment model for the target area is proposed in this paper.The model focuses on the construction of the assessment model framework.Firstly,the analytic hierarchy process and the grey relational analysis are applied to measure the importance of each target in the region through four indicators of the target hazard,striking urgency,damage advantage and mission relevance,respectively.Secondly,based on the damage mechanism of shock wave and fragments to target,the corresponding damage model is established,and the damage grade of each target in the evaluated area is obtained according to the damage criteria and grading standard.Finally,the model obtains the overall damage grade of the target area by employing the fuzzy comprehensive evaluation method,with synthesizing the importance and the damage grade of each target.Through the verification of an example,it demonstrates the certain feasibility of the model and provides a certain basis and reference for the subsequent research.

Budd-Chiari syndrome in China: A 30-year retrospective study on survival from a single center

AIM To investigate 30-year treatment outcomes associated with Budd-Chiari syndrome(BCS) at a tertiary hospital in China.METHODS A total of 256 patients diagnosed with primary BCS at our tertiary hospital between November 1983 and September 2013 were followed and retrospectively studied. Cumulative survival rates and cumulative mortality rates of major causes were calculated by Kaplan-Meier analysis, and the independent predictors of survival were identified using a Cox regression model. RESULTS Thirty-four patients were untreated; however, 222 patients were treated by medicine, surgery, or interventional radiology. Forty-four patients were lost to follow-up; however, 212 patients were followed, 67 of whom died. The symptom remission rates of treated and untreated patients were 81.1%(107/132) and 46.2%(6/13), respectively(P = 0.009). The cumulative 1-, 5-, 10-, 20-, and 30-year survival rates of the treated patients were 93.5%, 81.6%, 75.2%, 64.7%, and 58.2%, respectively; however, the 1-, 5-, 10-, 20-, and 30-year survival rates of the untreated patients were 70.8%, 70.8%, 53.1%, 0%, and unavailable, respectively(P = 0.007). Independent predictors of survival for treated patients were gastroesophageal variceal bleeding(HR = 3.043, 95%CI: 1.363-6.791, P = 0.007) and restenosis(HR = 4.610, 95%CI: 1.916-11.091, P = 0.001). The cumulative 1-, 5-, 10-, 20-, and 30-year mortality rates for hepatocellular carcinoma were 0%, 2.6%, 3.5%, 8%, and 17.4%, respectively.CONCLUSION Long-term survival is satisfactory for treated Chinese patients with BCS. Hepatocellular carcinoma is a chronic complication and should be monitored with long-term follow-up.

Characteristics structure analysis on debris cloud in the hypervelocity impact of disk projectile on thin plate

In this paper,the gauge points setting is introduced in the SPH simulation to analyze the debris cloud structure generated by the hypervelocity impact of disk projectile on thin plate.Compared with the experiments,more detailed information of the debris cloud structure can be classified from the numerical simulation.However,due to the solitary dispersion and overlap display of the particles in the SPH simulation,accurate comparison between numerical and experimental results is difficult to be performed.To track the velocity and spatial distribution of the particles in the debris cloud induced from disk and plate,gauge points are locally set in the single-layer profile in the SPH model.By analyzing the gauge points’spatial coordinate and velocity,the location and velocity of characteristic points in the debris cloud are determined.The boundary of debris cloud is achieved,as well as the fragments distribution outside the main structure of debris cloud.

Analysis on the resistive force in penetration of a rigid projectile

According to the dimensionless formulae of DOP(depth of penetration) of a rigid projectile into different targets,the resistive force which a target exerts on the projectile during the penetration of rigid projectile is theoretically analyzed.In particular,the threshold V_C of impact velocity applicable for the assumption of constant resistive force is formulated through impulse analysis.The various values of V_C corresponding to different pairs of projectile-target are calculated,and the consistency of the relative test data and numerical results is observed.

Ballistic performance of tungsten particle/metallic glass matrix composite long rod

In the present manuscript numerical analysis on the ballistic performance of a tungsten particle/metallic glass matrix(WP/MG) composite rod is conducted by integrating with related experimental investigations. In the corresponding finite element method(FEM) simulations a modified coupled thermomechanical constitutive model is employed to describe the mechanical properties of metallic glass(MG)matrix, and geometrical models of the WP/MG composite rod are established based on its inner structure. The deformation and failure characteristics of the rod and target materials are analyzed in detail,and the influences of various factors on the ballistic performance of the WP/MG composite long rod are discussed. Related analysis demonstrates that the penetrating performance of the WP/MG rod is similar to that of the tungsten fiber/metallic glass matrix(WF/MG) composite long rod, i.e., a "self-sharpening" behavior also occurs during the penetration process, and correspondingly its penetrating capability is better than that of the tungsten heavy alloy(WHA) rod. However, the mass erosion manner of the WP/MG rod is different and the erosion is relatively severe, thus its penetrating capability is a little lower compared with that of the WF/MG one. Moreover, the impact velocity and the target strength have significant influences on the ballistic performance of the WP/MG composite rod, whereas the effect of initial nose shape is very little.

Effect of interaction of refractories with Ni-based superalloy on inclusions during vacuum induction melting

This study documents laboratory-scale observation of the interactions between the Ni-based superalloy FGH4096 and refractories.Three different crucibles were tested—MgO,Al2O3,and MgO–spinel.We studied the variations in the compositions of the inclusions and the alloy–crucible interface with the reaction time using scanning electron microscopy equipped with energy dispersive X-ray spectroscopy and Xray diffraction.The results showed that the MgO and MgO–spinel crucibles form MgO-containing inclusions(Al–Mg oxides and Al–Mg–Ti oxides),whereas the inclusions formed when using the Al2O3 crucible are Al2O3 and Al–Ti oxides.We observed a new MgAl2O4 phase at the inner wall of the MgO crucible,with the alloy melted in the MgO crucible exhibiting fewer inclusions.No new phase occurred at the inner wall of the Al2O3 crucible.We discuss the mechanism of interaction between the refractories and the Ni-based superalloy.Physical erosion was found to predominate in the Al2O3 crucible,whereas dissolution and chemical reactions dominated in the MgO crucible.No reaction was observed between three crucibles and the Ti of the melt although the Ti content(3.8wt%)was higher than that of Al(2.1wt%).

Stability analyses of the mass abrasive projectile high-speed penetrating into concrete target. Part Ⅰ: Engineering model for the mass loss and nose-blunting of ogive-nosed projectiles

The mass loss and nose blunting of a projectile during high-speed deep penetration into concrete target may cause structural destruction and ballistic trajectory instability of the penetrator,obviously reducing the penetration efficiency of penetrator.Provided that the work of friction between projectile and target is totally transformed into the heat to melt penetrator material at its nose surface,an engineering model is established for the mass loss and nose-blunting of the ogive-nosed projectile.A dimensionless formula for the relative mass loss of projectile is obtained by introducing the dimensionless impact function I and geometry function N of the projectile.The critical value V c0of the initial striking velocity is formulated,and the mass loss of projectile tends to increase weakly nonlinearly with I/N when V0〉V c0,whilst the mass loss is proportional to the initial kinetic energy of projectile when V0

Stability analyses of the mass abrasive projectile high-speed penetrating into concrete target. Part Ⅱ: Structural stability analyses

The initial oblique and attacking angles as well as the asymmetrical nose abrasion may lead to bending or even fracture of a projectile,and the penetration efficiency decreases distinctly.The structural stability of a high-speed projectile non-normally penetrating into concrete and the parametric influences involved are analyzed with the mass abrasion taken into account.By considering the symmetrical or asymmetrical nose abrasion as well as the initial oblique and attacking angles,both the axial and the transverse drag forces acting on the projectile are derived.Based on the ideal elastic-plastic yield criterion,an approach is proposed for predicting the limit striking velocity（LSV）that is the highest velocity at which no yielding failure has occurred and the projectile can still maintain its integral structural stability.Furthermore,some particular penetration scenarios are separately discussed in detail.Based on the engineering model for the mass loss and nose-blunting of ogive-nose projectiles established in Part I of this study,the above approach is validated by several high-speed penetration tests.The analysis on parametric influences indicates that the LSV is reduced with an increase in the asymmetrical nose abrasion,thelength-diameter-ratio,and the concrete strength,as well as the oblique and attacking angles.Also,the LSV raises with an increase in the initial caliber-radius-head（CRH）and the dimensionless cartridge thickness of a projectile.

Analysis of the stress wave and rarefaction wave produced by hypervelocity impact of sphere onto thin plate

Shock wave is emitted into the plate and sphere when a sphere hypervelocity impacts onto a thin plate.The fragmentation and phase change of the material caused by the propagation and unloading of shock wave could result in the formation of debris cloud eventually.Propagation models are deduced based on one-dimensional shock wave theory and the geometry of sphere,which uses elliptic equations(corresponding to ellipsoid equations in physical space)to describe the propagation of shock wave and the rarefaction wave.The“Effective thickness”is defined as the critical plate thickness that ensures the rarefaction wave overtake the shock wave at the back of the sphere.The“Effective thickness”is directly related to the form of the debris cloud.The relation of the“Effective thickness”and the“Optimum thickness”is also discussed.The impacts of Al spheres onto Al plates are simulated within SPH to verify the propagation models and associated theories.The results show that the wave fronts predicted by the propagation models are closer to the simulation result at higher impact velocity.The curvatures of the wave fronts decrease with the increase of impact velocities.The predicted“Effective thickness”is consistent with the simulation results.The analysis about the shock wave propagation and unloading in this paper can provide a new sight and inspiration for the quantitative study of hypervelocity impact and space debris protection.

Research and development on hypervelocity impact protection using Whipple shield:An overview

Whipple shield,a dual-wall system,as well as its improved structures,is widely applied to defend the hypervelocity impact of space debris(projectile).This paper reviews the studies about the mechanism and process of protection against hypervelocity impacts using Whipple shield.Ground-based experiment and numerical simulation for hypervelocity impact and protection are introduced briefly.Three steps of the Whipple shield protection are discussed in order,including the interaction between the projectile and bumper,the movement and diffusion of the debris cloud,and the interaction between the debris cloud and rear plate.Potential improvements of the protection performance focusing on these three steps are presented.Representative works in the last decade are mentioned specifically.Some prospects and suggestions for future studies are put forward.

Effect of microstructure on short pulse duration shock initiation of TATB and initial response mechanism

Micro-TATB particles with different sizes and 3D nanoporous TATB architectures with different specific surface areas were prepared through recrystallization to study short pulse duration shock initiation properties by electric gun technology.For micro-TATB,the initiation threshold significantly decreases with TATB average size ranging from 79.7μm to 0.5μm.For 3D nanoporous TATB architecture,the initiation threshold decreases and then increases with specific surface areas increased from 9.6 m^2/g to36.2 m^2/g.The lowest initiation thresholds are obtained for the micro-TATB with average sizes of 1.3μm and 0.5μm,and 3D nanoporous TATB architecture with specific surface area of 22.4 m^2/g.The shock initiation thresholds of micro-TATB and 3D nanoporous TATB architectures show significantly decreases with the porosity increased.The decomposition reaction and thermal conductivity properties were further investigated to understand the initial response mechanism.High porosity provides more collapse sites to generate high temperature for formation of hot spots.The low thermal conductivity and decomposition temperature could enhance the formation and ignition of the hot spots,and initial decomposition reaction of TATB.The effect of the decomposition temperature is higher than that of the thermal conductivity on the shock initiation properties.The enhanced decomposition reaction could pro mote energy release and transfer process from the ignition to the combustio n.This work offe rs a new insight to understand the effects of microstructure on the shock initiation properties and the initial response mechanism of TATB.

The effects of compressibility and strength on penetration of long rod and jet

The approximate compressible model is adopted to study the effects of strength and compressibility on the penetration by WHA long rod and copper jet into semi-infinite target in detail. For WHA rod penetrating PMMA at 2 km/s <V <5 km/s, the compressibility has a significant effect on the penetration efficiency. We clarify how compressibility affects the penetration efficiency by changing the stagnation pressures of the rod and target. For WHA rod penetrating 4340 Steel and 6061-T6 Al at 2 km/s < V < 10 km/s, the effect of strength is strong and the effect of compressibility is negligible at lower impact velocity, whilst the effect of strength is weak and the effect of compressibility becomes stronger at higher impact velocity. For the copper jet penetrating 4030 Steel, 6061-T6 Al and PMMA. the virtual origin model is adopted, and the compressibility and strength are implicitly considered by the linear relation between the penetration velocity and impact velocity. The effects of compressibility and target resistance on penetration efficiency are studied. The results show that the target resistance has a significant effect on the penetration efficiency. Howver PMMA is much more compressible than copper and the huge difference of compressibility has a significant effect on the penetration by hypervelocity copper jet into PMMA.

Parametric study on mass loss of penetrators

Earth penetration weapon （EPW） is applicable for attacking underground targets protected by reinforced concrete and rocks. With increasing impact velocity, the mass loss/abrasion of penetrator increases, which significandy decreases the penetration efficiency due to the change of nose shape. The abrasion may induce instability of the penetrator, and lead to failure of its structure. A common disadvantage, i.e. dependence on corresponding experimen- tal results, exists in all the available formulae, which limits their ranges of application in estimating the mass loss of penetrator. In this paper, we conduct a parametric study on the mass loss of penetrator, and indicate that the mass loss of penetrator can be determined by seven variables, i.e., the initial impact velocity, initial nose shape, melting heat, shank diameter of projectile and density and strength of target as well as the aggregate hardness of target. Further discussion on factors dominant in the mass abrasion of penetrator are given, which may be helpful for optimizing the target or the projectile for defensive or offensive objectives, respectively.

Hexagonal arrangement of phospholipids in bilayer membranes

The phospholipid membrane plays a key role in myriad biological processes and phenomena, and the arrangement structure of membrane determines its function. However, the molecular arrangement structure of phospholipids in cell membranes is difficult to detect experimentally. On the basis of molecular dynamic simulations both in a non-destructive way and at native environment, we observed and confirmed that the phospholipids self-assemble to a hexagonal arrangement structure under physiological conditions. The underlying mechanism was revealed to be that there are hexagonal arrangement regions with a lower free energy around each lipid molecule. The findings potentially advance the understanding of biological functions of phospholipid bilayers.

Restenosis after recanalization for Budd-Chiari syndrome: Management and long-term results of 60 patients

BACKGROUND Budd-Chiari syndrome is defined as hepatic venous outflow tract obstruction.For Asian Budd-Chiari syndrome patients,the major treatment modality is recanalization(percutaneous transluminal angioplasty with or without stent implantation).The cumulative 1-,5-,and 10-year primary patency rates and survival rates are reported to be excellent or satisfactory,but the long-term outcome of patients with restenosis(the most common complication after recanalization)is unknown.AIM To explore the treatment strategy for restenosis in patients with Budd-Chiari syndrome after interventional therapy and to evaluate the long-term follow-up results.METHODS The clinical data and follow-up results of 60 patients with restenosis after interventional therapy from November 1983 to December 2013 were retrospectively analyzed.RESULTS Sixty patients with restenosis were retrospectively divided into a percutaneous transluminal angioplasty(PTA)group(40 patients)and a PTA+stent group(20 patients)according to the primary recanalization method.For the patients with restenosis in the PTA group,13 refused treatment,and 27 received further treatment;among these patients,five had a second restenosis,two had a third restenosis,and one had a fourth restenosis.For the patients with restenosis in the PTA+stent group,nine refused treatment,ten received PTA alone,and the other received PTA+stent implantation.Among the patients who received further treatment,five had a second restenosis,three had a third restenosis,and one had a fourth restenosis.The 1-,5-,10-,20-,and 25-year cumulative survival rates of the 38 patients who received further treatment after restenosis were 100%,78.3%,78.3%,70.5%,and 70.5%,respectively;however,for the 22 patients who refused treatment,the survival rates were 72.7%,45.9%,30.6%,10.2%,and unavailable,respectively(P<0.001).CONCLUSION Long-term follow-up after interventional therapy is very important.Active treatment for patients with restenosis can improve prognosis,and minimally invasive treatment strategies for restenosis allows to obtain satisfactory results.

Study of Magnetic Force Distribution for Electromagnetic V-shape Bending Forming of Small Size Flat Sheet

Electromagnetic V-shape bending of small size sheet blank is investigated numerically and experimentally. Three-dimensional electromagnetic field models are established to calculate the magnetic force distribution on the sheet by software ANSYS / EMAG. Series of electromagnetic V-shape bending forming experiments are presented,in which small size uniform pressure coil and big size round flat spiral coil are used. The results show that small size uniform pressure coil is not suitable for electromagnetic forming of small size flat sheet,and the coil is susceptible to failure such as bulging,ablation and cracking. When the plane dimension of round flat spiral coil is bigger than sheet blank sizes,the induced current crowding effect will be resulted which seriously influence the magnetic force distribution on the sheet. In this case,magnetic force distribution can be adjusted through the change of the relative position between coil and sheet,the desired deformation can be obtained finally. Therefore,big size round flat spiral coil can be well applied to electromagnetic V-shape bending forming of small size flat sheet.

Computational Assessment of the Expression-modulating Potential for Non-coding Variants

Large-scale genome-wide association studies(GWAS)and expression quantitative trait locus(eQTL)studies have identified multiple non-coding variants associated with genetic diseases by affecting gene expression.However,pinpointing causal variants effectively and efficiently remains a serious challenge.Here,we developed CARMEN,a novel algorithm to identify functional non-coding expression-modulating variants.Multiple evaluations demonstrated CARMEN’s superior performance over state-of-the-art tools.Applying CARMEN to GWAS and eQTL datasets further pinpointed several causal variants other than the reported lead single-nucleotide polymorphisms(SNPs).CARMEN scales well with the massive datasets,and is available online as a web server at http://carmen.gao-lab.org.