Developing new functional explosives that display high stability,good energy performance,and low sensitivity are one of the key directions of energetic materials research.In this work,two-dimensional(2D)Schiff-based e...Developing new functional explosives that display high stability,good energy performance,and low sensitivity are one of the key directions of energetic materials research.In this work,two-dimensional(2D)Schiff-based energetic covalent organic frameworks(COFs)are prepared based on triaminoguanidine salts with different anions as building blocks.Benefiting from the robust covalent bond in 2D extended polygons and strongπ-πinteractions in the eclipsed interlayers,the synthesized energetic COFs showed higher thermal stability and lower mechanical sensitivity than their precursor salts.More importantly,incorporating triaminoguanidine salts into COFs effectively increase the corrosion resistance to metal under high humidity conditions,which is due to the imine moieties in COFs functioning asπacceptors and offering strong bonding with metallic ions.This work provides a new pathway for the development of high-performance energetic materials.展开更多
Background There is a paucity of studies conducted in China on the outcomes of all live-birth extremely premature infants(EPIs)and there is no unifed recommendation on the active treatment of the minimum gestational a...Background There is a paucity of studies conducted in China on the outcomes of all live-birth extremely premature infants(EPIs)and there is no unifed recommendation on the active treatment of the minimum gestational age in the feld of perinatal medicine in China.We aimed to investigate the current treatment situation of EPIs and to provide evidence for formulating reasonable treatment recommendations.Methods We established a real-world ambispective cohort study of all live births in delivery rooms with gestational age(GA)between 24+0 and 27+6 weeks from 2010 to 2019.Results Of the 1163 EPIs included in our study,241(20.7%)survived,while 849(73.0%)died in the delivery room and 73(6.3%)died in the neonatal intensive care unit.Among all included EPIs,862(74.1%)died from withholding or withdrawal of care.Regardless of stratifcation according to GA or birth weight,the proportion of total mortality attributable to withdrawal of care is high.For infants with the GA of 24 weeks,active treatment did not extend their survival time(P=0.224).The survival time without severe morbidity of the active treatment was signifcantly longer than that of withdrawing care for infants older than 25 weeks(P<0.001).Over time,the survival rate improved,and the withdrawal of care caused by socioeconomic factors and primary nonintervention were reduced signifcantly(P<0.001).Conclusions The mortality rate of EPIs is still high.Withdrawal of care is common for EPIs with smaller GA,especially in the delivery room.It is necessary to use a multi-center,large sample of real-world data to fnd the survival limit of active treatment based on our treatment capabilities.展开更多
We propose a multi-focus image fusion method, in which a fully convolutional network for focus detection(FD-FCN) is constructed. To obtain more precise focus detection maps, we propose to add skip layers in the networ...We propose a multi-focus image fusion method, in which a fully convolutional network for focus detection(FD-FCN) is constructed. To obtain more precise focus detection maps, we propose to add skip layers in the network to make both detailed and abstract visual information available when using FD-FCN to generate maps. A new training dataset for the proposed network is constructed based on dataset CIFAR-10. The image fusion algorithm using FD-FCN contains three steps: focus maps are obtained using FD-FCN, decision map generation occurs by applying a morphological process on the focus maps, and image fusion occurs using a decision map. We carry out several sets of experiments, and both subjective and objective assessments demonstrate the superiority of the proposed fusion method to state-of-the-art algorithms.展开更多
基金supported the National Natural Science Foundation of China(Nos.22175155,21825106 and 22275168)the Henan Science Fund for Excellent Young Scholars(No.212300410084)the opening project of State Key Laboratory of Explosion Science and Technology(Beijing Institute of Technology)(No.KFJJ22–05 M)。
文摘Developing new functional explosives that display high stability,good energy performance,and low sensitivity are one of the key directions of energetic materials research.In this work,two-dimensional(2D)Schiff-based energetic covalent organic frameworks(COFs)are prepared based on triaminoguanidine salts with different anions as building blocks.Benefiting from the robust covalent bond in 2D extended polygons and strongπ-πinteractions in the eclipsed interlayers,the synthesized energetic COFs showed higher thermal stability and lower mechanical sensitivity than their precursor salts.More importantly,incorporating triaminoguanidine salts into COFs effectively increase the corrosion resistance to metal under high humidity conditions,which is due to the imine moieties in COFs functioning asπacceptors and offering strong bonding with metallic ions.This work provides a new pathway for the development of high-performance energetic materials.
基金This work was supported by the National Assisted Reproductive and Eugenics Engineering Technology Research Center and Key Laboratory of Reproductive Endocrinology Ministry of Education Open Project,2017.11-2022.10,the Shandong Key Research and Development Project(2018GSF118163)Shandong Provincial Medical Health Technology Development Project(2017WS009).
文摘Background There is a paucity of studies conducted in China on the outcomes of all live-birth extremely premature infants(EPIs)and there is no unifed recommendation on the active treatment of the minimum gestational age in the feld of perinatal medicine in China.We aimed to investigate the current treatment situation of EPIs and to provide evidence for formulating reasonable treatment recommendations.Methods We established a real-world ambispective cohort study of all live births in delivery rooms with gestational age(GA)between 24+0 and 27+6 weeks from 2010 to 2019.Results Of the 1163 EPIs included in our study,241(20.7%)survived,while 849(73.0%)died in the delivery room and 73(6.3%)died in the neonatal intensive care unit.Among all included EPIs,862(74.1%)died from withholding or withdrawal of care.Regardless of stratifcation according to GA or birth weight,the proportion of total mortality attributable to withdrawal of care is high.For infants with the GA of 24 weeks,active treatment did not extend their survival time(P=0.224).The survival time without severe morbidity of the active treatment was signifcantly longer than that of withdrawing care for infants older than 25 weeks(P<0.001).Over time,the survival rate improved,and the withdrawal of care caused by socioeconomic factors and primary nonintervention were reduced signifcantly(P<0.001).Conclusions The mortality rate of EPIs is still high.Withdrawal of care is common for EPIs with smaller GA,especially in the delivery room.It is necessary to use a multi-center,large sample of real-world data to fnd the survival limit of active treatment based on our treatment capabilities.
基金Project supported by the National Natural Science Foundation of China(No.61801190)the Natural Science Foundation of Jilin Province,China(No.20180101055JC)the Outstanding Young Talent Foundation of Jilin Province,China(No.20180520029JH)。
文摘We propose a multi-focus image fusion method, in which a fully convolutional network for focus detection(FD-FCN) is constructed. To obtain more precise focus detection maps, we propose to add skip layers in the network to make both detailed and abstract visual information available when using FD-FCN to generate maps. A new training dataset for the proposed network is constructed based on dataset CIFAR-10. The image fusion algorithm using FD-FCN contains three steps: focus maps are obtained using FD-FCN, decision map generation occurs by applying a morphological process on the focus maps, and image fusion occurs using a decision map. We carry out several sets of experiments, and both subjective and objective assessments demonstrate the superiority of the proposed fusion method to state-of-the-art algorithms.
