Chronic obstructive pulmonary disease(COPD), lung cancer(LC) and tuberculosis(TB) are common chronic lung diseases that generate a large disease burden and significant health care resource use in China. The aim of thi...Chronic obstructive pulmonary disease(COPD), lung cancer(LC) and tuberculosis(TB) are common chronic lung diseases that generate a large disease burden and significant health care resource use in China. The aim of this study was to quantify spatial patterns and effects of air pollution and meteorological factors on hospitalization of COPD, LC and TB in Beijing. Daily counts of hospitalization for 2010 were obtained from the Beijing Urban Employees Basic Medical Insurance(UEBMI) system.Bayesian hierarchical Poisson regression models were applied to identify spatial patterns of hospitalization for COPD, LC and TB at the district level and explore associations with inhalable particulate matter(aerodynamic diameter <10 μm, PM10), sulfur dioxide(SO2), nitrogen dioxide(NO2), mean temperature and relative humidity. There were 18,882, 14,295 and 2,940 counts of hospitalizations for COPD, LC and TB respectively, in Beijing in 2010. Clusters of high relative risk were in different locations for the three diseases. The effect of relative humidity on COPD hospitalization was most significant with a relative risk(RR) of 1.070(95%CI: 1.054, 1.086) per one percent increase. For lung cancer hospitalization, exposure to ambient SO2 was associated with a RR of 1.034(95%CI: 1.011, 1.058) per μg m–3 increase. For tuberculosis, the effect of mean temperature was significant with a RR of 1.107(95%CI: 1.038, 1.180) per °C increase. Risk factors and spatial patterns were different for hospitalization of non-infectious and infectious chronic lung disease in Beijing. Even over a short time period(one year), associations were apparent with air pollution and meteorological factors.展开更多
Summary What is already known about this topic?Long-term temperature variability(TV)has been examined to be associated with cardiovascular disease(CVD).TV-related dyslipidemia helps us understand the mechanism of how ...Summary What is already known about this topic?Long-term temperature variability(TV)has been examined to be associated with cardiovascular disease(CVD).TV-related dyslipidemia helps us understand the mechanism of how climate change affects CVD.What is added by this report?Based on the China Health and Retirement Longitudinal Study(CHARLS)from 2011 to 2018,this study estimated the long-term effect of TV on dyslipidemia in middle-aged and elderly adults.展开更多
文摘Chronic obstructive pulmonary disease(COPD), lung cancer(LC) and tuberculosis(TB) are common chronic lung diseases that generate a large disease burden and significant health care resource use in China. The aim of this study was to quantify spatial patterns and effects of air pollution and meteorological factors on hospitalization of COPD, LC and TB in Beijing. Daily counts of hospitalization for 2010 were obtained from the Beijing Urban Employees Basic Medical Insurance(UEBMI) system.Bayesian hierarchical Poisson regression models were applied to identify spatial patterns of hospitalization for COPD, LC and TB at the district level and explore associations with inhalable particulate matter(aerodynamic diameter <10 μm, PM10), sulfur dioxide(SO2), nitrogen dioxide(NO2), mean temperature and relative humidity. There were 18,882, 14,295 and 2,940 counts of hospitalizations for COPD, LC and TB respectively, in Beijing in 2010. Clusters of high relative risk were in different locations for the three diseases. The effect of relative humidity on COPD hospitalization was most significant with a relative risk(RR) of 1.070(95%CI: 1.054, 1.086) per one percent increase. For lung cancer hospitalization, exposure to ambient SO2 was associated with a RR of 1.034(95%CI: 1.011, 1.058) per μg m–3 increase. For tuberculosis, the effect of mean temperature was significant with a RR of 1.107(95%CI: 1.038, 1.180) per °C increase. Risk factors and spatial patterns were different for hospitalization of non-infectious and infectious chronic lung disease in Beijing. Even over a short time period(one year), associations were apparent with air pollution and meteorological factors.
基金Supported by from National Natural Science Foundation Project of China(81872590 and 41761144056).
文摘Summary What is already known about this topic?Long-term temperature variability(TV)has been examined to be associated with cardiovascular disease(CVD).TV-related dyslipidemia helps us understand the mechanism of how climate change affects CVD.What is added by this report?Based on the China Health and Retirement Longitudinal Study(CHARLS)from 2011 to 2018,this study estimated the long-term effect of TV on dyslipidemia in middle-aged and elderly adults.
