Scene classification of high-resolution remote sensing (HRRS) image is an important research topic and has been applied broadly in many fields. Deep learning method has shown its high potential to in this domain, owin...Scene classification of high-resolution remote sensing (HRRS) image is an important research topic and has been applied broadly in many fields. Deep learning method has shown its high potential to in this domain, owing to its powerful learning ability of characterizing complex patterns. However the deep learning methods omit some global and local information of the HRRS image. To this end, in this article we show efforts to adopt explicit global and local information to provide complementary information to deep models. Specifically, we use a patch based MS-CLBP method to acquire global and local representations, and then we consider a pretrained CNN model as a feature extractor and extract deep hierarchical features from full-connection layers. After fisher vector (FV) encoding, we obtain the holistic visual representation of the scene image. We view the scene classification as a reconstruction procedure and train several class-specific stack denoising autoencoders (SDAEs) of corresponding class, i.e., one SDAE per class, and classify the test image according to the reconstruction error. Experimental results show that our combination method outperforms the state-of-the-art deep learning classification methods without employing fine-tuning.展开更多
Osteosarcoma (OS), chondrosarcoma (CSA), and Ewings sarcoma (ES) are the most common primary malignancies of bone, and are rare diseases. As with all sarcomas, the prognosis of these diseases ultimately depends on the...Osteosarcoma (OS), chondrosarcoma (CSA), and Ewings sarcoma (ES) are the most common primary malignancies of bone, and are rare diseases. As with all sarcomas, the prognosis of these diseases ultimately depends on the presence of metastatic disease. Survival is therefore closely linked with the biology and metastatic potential of a particular bone tumor’s cells. Here we describe a significant correlation of aldehyde dehydrogenase (ALDH) activity and the presence/absence of distant metastases in ten consecutive cases of human bone sarcomas. Additionally, cultured human CSA cells, which are historically chemo- and radio-resistant, may be sensitive to the ALDH inhibitor, disulfiram. While it is premature to draw broad conclusions from such a small series, the importance of ALDH activity and inhibition in the metastatic potential of primary bone sarcomas should be investigated further.展开更多
文摘Scene classification of high-resolution remote sensing (HRRS) image is an important research topic and has been applied broadly in many fields. Deep learning method has shown its high potential to in this domain, owing to its powerful learning ability of characterizing complex patterns. However the deep learning methods omit some global and local information of the HRRS image. To this end, in this article we show efforts to adopt explicit global and local information to provide complementary information to deep models. Specifically, we use a patch based MS-CLBP method to acquire global and local representations, and then we consider a pretrained CNN model as a feature extractor and extract deep hierarchical features from full-connection layers. After fisher vector (FV) encoding, we obtain the holistic visual representation of the scene image. We view the scene classification as a reconstruction procedure and train several class-specific stack denoising autoencoders (SDAEs) of corresponding class, i.e., one SDAE per class, and classify the test image according to the reconstruction error. Experimental results show that our combination method outperforms the state-of-the-art deep learning classification methods without employing fine-tuning.
文摘Osteosarcoma (OS), chondrosarcoma (CSA), and Ewings sarcoma (ES) are the most common primary malignancies of bone, and are rare diseases. As with all sarcomas, the prognosis of these diseases ultimately depends on the presence of metastatic disease. Survival is therefore closely linked with the biology and metastatic potential of a particular bone tumor’s cells. Here we describe a significant correlation of aldehyde dehydrogenase (ALDH) activity and the presence/absence of distant metastases in ten consecutive cases of human bone sarcomas. Additionally, cultured human CSA cells, which are historically chemo- and radio-resistant, may be sensitive to the ALDH inhibitor, disulfiram. While it is premature to draw broad conclusions from such a small series, the importance of ALDH activity and inhibition in the metastatic potential of primary bone sarcomas should be investigated further.