To improve the separation capacity of uranium in aqueous solutions, 3R-MoS2 nanosheets were prepared with molten salt electro- lysis and further modified with polypyrrole (PPy) to synthesize a hybrid nanoadsorbent (PP...To improve the separation capacity of uranium in aqueous solutions, 3R-MoS2 nanosheets were prepared with molten salt electro- lysis and further modified with polypyrrole (PPy) to synthesize a hybrid nanoadsorbent (PPy/3R-MoS2). The preparation conditions of PPy/3R- MoS2 were investigated and the obtained nanosheets were characterized with scanning electron microscope (SEM), high resolution transmis- sion electron microscope (HRTEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectro- scopy (XPS). The results showed that PPy/3R-MoS2 exhibited enhanced adsorption capacity toward U(VI) compared to pure 3R-MoS2 and PPy;the maximum adsorption was 200.4 mg/g. The adsorption mechanism was elucidated with XPS and FTIR: (1) negatively charged PPy/3R-MoS2 nanosheets attracted by an electrostatic interaction;(2) exposed C, N, Mo, and S atoms complexed with U(VI) through co- ordination;(3) Mo in the complex partly reduced the adsorbed U(VI) to U(IV), which further regenerated the adsorption point and continu- ously adsorbed U(VI). The design of the PPy/3R-MoS2 composite with a high adsorption capacity and chemical stability provides a new direc- tion for the removal of radionuclide.展开更多
In this work,we proposed a new U(Ⅵ)removal strategy combining adsorption and photocatalytic reduction by the PMo_(12)/UiO-66 heterojunctions.The PMo_(12)has been encapsulated in the cavities of Ui O-66 by a one-step ...In this work,we proposed a new U(Ⅵ)removal strategy combining adsorption and photocatalytic reduction by the PMo_(12)/UiO-66 heterojunctions.The PMo_(12)has been encapsulated in the cavities of Ui O-66 by a one-step hydrothermal method,and the PMo_(12)/UiO-66 exhibited high adsorption capacity and photocatalytic activity.The maximal theoretical sorption capacity of U(Ⅵ)on 15%PMo_(12)/UiO-66 reached225.36 mg/g and the photoreduction rate of 15%PMo_(12)/UiO-66 is about thirty times as much as UiO-66.Under the light irradiation,the photogenerated electrons rapidly transport from UiO-66 to PMo_(12),and the photo-generated electrons could efficiently reduce the pre-enriched U(Ⅵ)to U(IV).This work provides new insights into remediation of the radioactive environment.展开更多
Background:DNA methylation is a key heritable epigenetic modification that plays a crucial role in transcriptional regulation and therefore a broad range of biological processes.The complex patterns of DNA methylation...Background:DNA methylation is a key heritable epigenetic modification that plays a crucial role in transcriptional regulation and therefore a broad range of biological processes.The complex patterns of DNA methylation highlight the significance of the profiling the DNA methylation landscape.Results:In this review,the main high-throughput detection technologies are summarized,and then the three trends of computational estimation of DNA methylation levels were analyzed,especially the expanding of the methylation data with lower coverage.Furthermore,the detection methods of differential methylation patterns for sequencing and array data were presented.Conclusions:More and more research indicated the great importance of DNA methylation changes across different diseases,such as cancers.Although a lot of enormous progress has been made in understanding the role of DNA methylation,only few methylated genes or functional elements serve as clinically relevant cancer biomarkers.The bottleneck in DNA methylation advances has shifted from data generation to data analysis.Therefore,it is meaningful to develop machine learning models for computational estimation of methylation profiling and identify the potential biomarkers.展开更多
基金the National Nat-ural Science Foundation of China(Nos.21906019,21906018,21561002,21866004,and 21866003)the Sci-ence&Technology Support Program of Jiangxi Province,China(No.2018ACB21007)+1 种基金the Jiangxi Program of Aca-demic and Technical Leaders of Major Disciplines,China(No.20182BCB22011)the Project of the Jiangxi Provincial Department of Education,China(Nos.GJJ160550,GJJ180385,and GJJ180400).
文摘To improve the separation capacity of uranium in aqueous solutions, 3R-MoS2 nanosheets were prepared with molten salt electro- lysis and further modified with polypyrrole (PPy) to synthesize a hybrid nanoadsorbent (PPy/3R-MoS2). The preparation conditions of PPy/3R- MoS2 were investigated and the obtained nanosheets were characterized with scanning electron microscope (SEM), high resolution transmis- sion electron microscope (HRTEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectro- scopy (XPS). The results showed that PPy/3R-MoS2 exhibited enhanced adsorption capacity toward U(VI) compared to pure 3R-MoS2 and PPy;the maximum adsorption was 200.4 mg/g. The adsorption mechanism was elucidated with XPS and FTIR: (1) negatively charged PPy/3R-MoS2 nanosheets attracted by an electrostatic interaction;(2) exposed C, N, Mo, and S atoms complexed with U(VI) through co- ordination;(3) Mo in the complex partly reduced the adsorbed U(VI) to U(IV), which further regenerated the adsorption point and continu- ously adsorbed U(VI). The design of the PPy/3R-MoS2 composite with a high adsorption capacity and chemical stability provides a new direc- tion for the removal of radionuclide.
基金financially supported by the National Natural Science Foundation of China(Nos.21866004,21866003,22066003,22076022,22006004)the Defense Industrial Technology Development Program(No.JCKY2019401C004)+2 种基金the Open Fund of Jiangxi Province Key Laboratory of Synthetic Chemistry(No.JXSC202012)the Open Fund of State Key Laboratory of Nuclear Resources and Environment(No.NRE1924)the Graduate Innovation Fund of East China University of Technology(No.DHYC-202134)。
文摘In this work,we proposed a new U(Ⅵ)removal strategy combining adsorption and photocatalytic reduction by the PMo_(12)/UiO-66 heterojunctions.The PMo_(12)has been encapsulated in the cavities of Ui O-66 by a one-step hydrothermal method,and the PMo_(12)/UiO-66 exhibited high adsorption capacity and photocatalytic activity.The maximal theoretical sorption capacity of U(Ⅵ)on 15%PMo_(12)/UiO-66 reached225.36 mg/g and the photoreduction rate of 15%PMo_(12)/UiO-66 is about thirty times as much as UiO-66.Under the light irradiation,the photogenerated electrons rapidly transport from UiO-66 to PMo_(12),and the photo-generated electrons could efficiently reduce the pre-enriched U(Ⅵ)to U(IV).This work provides new insights into remediation of the radioactive environment.
基金supported by the National Natural Science Foundation of China(No.61872063)and Shenzhen Science and Technology Program(No.JCYJ20210324140407021).
文摘Background:DNA methylation is a key heritable epigenetic modification that plays a crucial role in transcriptional regulation and therefore a broad range of biological processes.The complex patterns of DNA methylation highlight the significance of the profiling the DNA methylation landscape.Results:In this review,the main high-throughput detection technologies are summarized,and then the three trends of computational estimation of DNA methylation levels were analyzed,especially the expanding of the methylation data with lower coverage.Furthermore,the detection methods of differential methylation patterns for sequencing and array data were presented.Conclusions:More and more research indicated the great importance of DNA methylation changes across different diseases,such as cancers.Although a lot of enormous progress has been made in understanding the role of DNA methylation,only few methylated genes or functional elements serve as clinically relevant cancer biomarkers.The bottleneck in DNA methylation advances has shifted from data generation to data analysis.Therefore,it is meaningful to develop machine learning models for computational estimation of methylation profiling and identify the potential biomarkers.