An experimental model of schizophrenia was established using dizocilpine (MK-801). Rats were intragastrically administered with Wendan decoction or clozapine for 21 days prior to establishing the model. The results ...An experimental model of schizophrenia was established using dizocilpine (MK-801). Rats were intragastrically administered with Wendan decoction or clozapine for 21 days prior to establishing the model. The results revealed that the latency of schizophrenia model rats to escape from the hidden platform in the Morris water maze was significantly shortened after administration of Wendan decoction or clozapine. In addition, the treated rats crossed the platform significantly more times than the untreated model rats. Moreover, the rate of successful long-term potentiation induction in the Wendan decoction group and clozapine group were also obviously increased compared with the model group, and the population spike peak latency was significantly shortened. These experimental findings suggest that Wendan decoction can improve the learning and memory ability of schizophrenic rats to the same extent as clozapine treatment.展开更多
The reflection and transmission of a finite-power Airy beam incident on a dielectric slab are investigated by an analytical method.Based on the plane-wave angular spectrum expansion and Fresnel approximation,the analy...The reflection and transmission of a finite-power Airy beam incident on a dielectric slab are investigated by an analytical method.Based on the plane-wave angular spectrum expansion and Fresnel approximation,the analytical expressions of the reflected field,internal field as well as transmitted field in each region are obtained.Through numerical simulations,the intensity distributions of the incident beam,reflected beam,internal beam as well as transmitted beam are presented at oblique incidence.Besides,we also compare the intensity distributions of the geometrical-optics beam field,the first order beam mode field and the actual beam field,which indicates that the contribution of each order beam mode field to the actual beam field is related to the refractive index of the dielectric slab.Meanwhile,the reflection characteristics of the Airy beams in the special cases of Brewster incidence and total reflection are investigated.Finally,the effects of the optical thickness and refractive index of the dielectric slab on the peak intensity distributions and beam shifts of the reflected and transmitted beams are also discussed in detail.The analytical and numerical results will be useful to analyze the propagation dynamics of Airy beam in the dielectric slab and provide some theoretical supports to the design of optical film.展开更多
基金sponsored by the Natural Science Foundation of China (No. 81160423)Research Plan of Traditional Chinese Medicine of Jiangxi Province Department of Public Health (No. 2009A054)Jiangxi Provincial Youth Science Fund Project (No. GJJ11190)
文摘An experimental model of schizophrenia was established using dizocilpine (MK-801). Rats were intragastrically administered with Wendan decoction or clozapine for 21 days prior to establishing the model. The results revealed that the latency of schizophrenia model rats to escape from the hidden platform in the Morris water maze was significantly shortened after administration of Wendan decoction or clozapine. In addition, the treated rats crossed the platform significantly more times than the untreated model rats. Moreover, the rate of successful long-term potentiation induction in the Wendan decoction group and clozapine group were also obviously increased compared with the model group, and the population spike peak latency was significantly shortened. These experimental findings suggest that Wendan decoction can improve the learning and memory ability of schizophrenic rats to the same extent as clozapine treatment.
基金the National Natural Science Foundation of China(Grant Nos.62071359,61975158,62001377,and 61801349)China Postdoctoral Science Foundation(Grant No.2016M602770)+3 种基金Natural Science Basic Research Plan in Shaanxi Province of China(Grant Nos.2019JQ405,2019JM-238,2020JM-192,and 2021JM-135)Natural Science Basic Research Program of Shaanxi,China(Grant No.2020JQ-331)Postdoctoral Science Foundation in Shaanxi Province and the Fundamental Research Funds for the Central Universities,Scientific Research Program Funded by Shaanxi Provincial Education Department(Grant No.20JS059)the Open Foundation of Laboratory of Pinghu,Pinghu,China。
文摘The reflection and transmission of a finite-power Airy beam incident on a dielectric slab are investigated by an analytical method.Based on the plane-wave angular spectrum expansion and Fresnel approximation,the analytical expressions of the reflected field,internal field as well as transmitted field in each region are obtained.Through numerical simulations,the intensity distributions of the incident beam,reflected beam,internal beam as well as transmitted beam are presented at oblique incidence.Besides,we also compare the intensity distributions of the geometrical-optics beam field,the first order beam mode field and the actual beam field,which indicates that the contribution of each order beam mode field to the actual beam field is related to the refractive index of the dielectric slab.Meanwhile,the reflection characteristics of the Airy beams in the special cases of Brewster incidence and total reflection are investigated.Finally,the effects of the optical thickness and refractive index of the dielectric slab on the peak intensity distributions and beam shifts of the reflected and transmitted beams are also discussed in detail.The analytical and numerical results will be useful to analyze the propagation dynamics of Airy beam in the dielectric slab and provide some theoretical supports to the design of optical film.