“课程思政”视角下研究生高等生物化学课程建设的实践与探索

课程思政是实现研究生思想政治教育任务目标,落实“三全育人”的有效途径。高等生物化学是食品及生命科学相关专业的一门重要核心课。本文以高等生物化学课程为例,结合课程教学面临的问题,通过对课程思政教学目标的制定、教学内容的优化、思政元素融入课堂教学、教学方法和手段的适当运用以及考核方式的完善等方面的探索,建构了新形势下研究生高等生物化学课程建设的具体举措,旨在为“大思政”格局下生物学相关领域课程建设提供参考和借鉴。

A green method to synthesize flowerlike Fe(OH)3 microspheres for enhanced adsorption performance toward organic and heavy metal pollutants

Dyestuffs and heavy metal ions in water are seriously harmful to the ecological environment and human health. Three-dimensional （3D） flowerlike Fe（OH）3 microspheres were synthesized through a green yet low-cost injection method, for the removal of organic dyes and heavy metal ions. The Fe（OH）3 microspheres were characterized by thermal gravimetric analysis （TGA）, Fourier transform infrared （FT-IR}, and transmission electron microscopy （TEM） techniques. The adsorption kinetics of Congo Red （CR） on Fe（OH）3 microspheres obeyed the pseudo-second-order model. Cr6＋ and Pb2＋ adsorption behaviors on Fe（OH）3 microspheres followed the Langmuir isotherm model. The maximum adsorption capacities of the synthesized Fe（OH）3 were 308, 52.94, and 75.64 mg/g for CR, Cr6＋, and Pb2＋ respectively. The enhanced adsorption performance originated from its surface properties and large specific surface area of 250 m2/g. The microspheres also have excellent adsorption stability and recyclability. Another merit of the Fe（OH）3 material is that it also acts as a Fenton-like catalyst. These twin functionalities （both as adsorbent and Fenton-like catalyst） give the synthesized Fe（OH）3 microspheres great potential in the field of water treatment.

Light-Harvesting Artificial Cells for the Generation of ATP and NADPH

The bottom-up construction of self-powered artificial cells is significant to understand the energy supply and metabolism of nature cells.Here,we demonstrate an efficient manner to build thylakoid-containing artificial cells,which continuously convert light energy into chemical energy to supply adenosine 5'-triphosphate(ATP)under light illumination.The production of ATP supplies energy to promote the biological enzyme cascade reactions,where glucose is transformed into glucose 6-phosphate(G6P)under the catalysis of hexokinase(HK).G6P was further converted to gluconolactone 6-phosphate(PG)in the presence of 6-phosphate dehydrogenase(G6PDH),meanwhile NADP^(+) was converted to nicotinamide adenine dinucleotide phosphate(NADPH).The self-powered artificial cells were demonstrated to generate ATP and NADPH successively,which provided a way for building more complicated artificial cells.

Template-free synthesis of inorganic hollow spheres at water/“water-brother”interfaces as Fenton-like reagents for water treatment

This paper reports a template-free method to synthesize a series of inorganic hollow spheres（IHSs）including Cu-1,Cu-2,Ni-1,Ni-2 based on mineralization reactions at water/＂water-brother＂ interfaces. ＂Water-brother＂ was defined as a solvent which is miscible with water,such as ethanol and acetone. The water/＂water-brother＂ interfaces are very different from water/oil interfaces. The ＂water-brother＂ solvent will usually form a homogenous phase with water. Interestingly,in our method,these interfaces can be formed,observed and utilized to synthesize hollow spheres. Utilizing the unique porous properties of the spheres,their potential application in water treatment was demonstrated by using Cu-1 IHSs as Fenton-like reagents for adsorption and decomposition of Congo Red from aqueous solution. The final adsorption equilibrium was achieved after 30 min with the maximum adsorption capacity of 86.1 mg/g,and 97.3% removal of the dye in 80 min after adsorption equilibrium. The IHSs can be reused as least 5 times after treatment by Na OH.This method is facile and suitable for large-scale production,and shows great potential for watertreatment. 更多

CdTe-paper-based Visual Sensor for Detecting Methyl Viologen

This study developed a method on detecting methyl viologen(paraquat)using a CdTe-paper-based visual sensor.The CdTe Qdots were immobilized on the paper using glycerin.The volume percentages of CdTe in glycerin were optimized to be 50%.The sensing principle is that the methyl viologen quenches the fluorescence intensity of CdTe Qdots in a concentration dependent manner.The sensor is linearly response to the logarithm concentration of the methyl viologen in the range from 0.39μmol/L to 3.89 mmol/L with a detection limit of 0.16μmol/L and the corre-lation coefficient R^(2) of 0.99.Three parallel experiments at the methyl viologen concentration of 38.89μmol/L give a relative error of 2.45%,which indicates a good reproducibility.The sensor is not disturbed by other pestisides in-cluding omethoate,anilofos,machete and glyphosate isopropylamine salt.The advantages of this sensor are dis-posable,stable,convenient,and easy to operate.

Reversible conductivity recovery of highly sensitive flexible devices by water vapor

With decreasing size of integrated circuits in wearable electronic devices,the circuit is more susceptible to aging or fracture problem,subsequently decreasing the transmission efficiency of electricity.Micro-healing represents a good approach to solve this problem.Herein,we report a water vapor method to repair microfiber-based electrodes by precise positioning and rapid healing at their original fracture sites.To realize this micro-level conducting healing,we utilize a bimaterial composed of polymeric microfibers as healing agents and electrically conductive species on its surface.This composite electrode shows a high-performance conductivity,great transparency,and ultra-flexibility.The transmittance of our electrode could reach up to 88 and 90%with a sheet resistance of 1 and 2.8Ωsq^(−1),respectively,which might be the best performance among Au-based materials as we know.Moreover,after tensile failure,water vapor is introduced to mediate heat transfer for the healing process,and within seconds the network electrode could be healed along with recovering of its resistance.The recovering process could be attributed to the combination of adhesion force and capillary force at this bimaterial interface.Finally,this functional network is fabricated as a wearable pressure/strain sensing device.It shows excellent stretchability and mechanical durability upon 1000 cycles.