Research Progress of Aromatic Bed Curtains for Aiding Sleep Based on Lavender Microcapsule Technique

In this paper, the preparation technique of lavender essential oil microcapsules and the construction method of aromatic textiles were expounded, and the research status of bed curtains and lavender microcapsules at home and abroad was analyzed and studied from the perspective of application in textiles. The application of lavender essential oil to bed curtains through the microcapsule technique was put forward to allow lavender essential oil to play its role of helping sleep in bed curtains. This paper expounded the material selection and preparation technique of lavender microcapsule agents, and put forward the preparation method of microcapsules with mixed solutions of pure Chinese medicine extracts and natural essences as core material and high-viscosity epoxy resin as wall materials. The post-processing techniques and the spray ironing method for clothing were studied and developed, and these techniques and methods were applied to bed curtains, and good results were obtained.

Identification of Hub Genes Associated with Hepatocellular Carcinoma Prognosis by Bioinformatics Analysis

Objective: This study aimed to identify hub genes that are associated with hepatocellular carcinoma (HCC) prognosis by bioinformatics analysis. Methods: Data were collected from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) liver HCC datasets. The robust rank aggregation algorithm was used in integrating the data on differentially expressed genes (DEGs). Online databases DAVID 6.8 and REACTOME were used for gene ontology and pathway enrichment analysis. R software version 3.5.1, Cytoscape, and Kaplan-Meier plotter were used to identify hub genes. Results: Six GEO datasets and the TCGA liver HCC dataset were included in this analysis. A total of 151 upregulated and 245 downregulated DEGs were identified. The upregulated DEGs most significantly enriched in the functional categories of cell division, chromosomes, centromeric regions, and protein binding, whereas the downregulated DEGs most significantly enriched in the epoxygenase P450 pathway, extracellular region, and heme binding, with respect to biological process, cellular component, and molecular function analysis, respectively. Upregulated DEGS most significantly enriched the cell cycle pathway, whereas downregulated DEGs most significantly enriched the metabolism pathway. Finally, 88 upregulated and 40 downregulated genes were identified as hub genes. The top 10 upregulated hub DEGs were CDK1, CCNB1, CCNB2, CDC20, CCNA2, AURKA, MAD2L1, TOP2A, BUB1B and BUB1. The top 10 downregulated hub DEGs were ESR1, IGF1, FTCD, CYP3A4, SPP2, C8A, CYP2E1, TAT, F9 and CYP2C9. Conclusions: This study identified several upregulated and downregulated hub genes that are associated with the prognosis of HCC patients. Verification of these results using in vitro and in vivo studies is warranted.

Organochlorine compounds and polycyclic aromatic hydrocarbons in surface sediment from Baiyangdian Lake,North China:Concentrations,sources profiles and potential risk

Organochlorine pesticides （OCPs）, polychlorinated biphenyls （PCBs）, and polycyclic aromatic hydrocarbons （PAHs） were determined in nineteen surface sediment samples collected from Baiyangdian Lake and its inflowing river （Fuhe River） in North China. Total concentrations of OCPs, PCBs and PAHs in sediments ranged from 5.4 to 707.6 ng]g, 2.3 to 197.8 ng/g, and 101.3 to 6360.5 ng]g, respectively. The levels of contaminants in Fuhe River were significantly higher than those in Baiyandian Lake. For hexachlorocyclohexane （HCHs） and dichlorodiphenytrich/oroethanes （DDTs）, α-HCH and p,p＇-DDT were predominant isomers; while for PCBs, PCB 28/31, PCB 40/103, PCB 60, PCB 101, and PCB 118 were predominant congeners. Possible sources derived from historical usage for OCPs and incomplete combustion fuel, wood, and coal and exhaustion of boats or cars for PAHs. Risk assessment of sediment indicated that sediments in Fuhe River were likely to pose potential biological adverse impact.

Analysis of Factors Influencing the Complications of Solitaire AB Stent Mechanical Thrombectomy in Patients with Acute Intracranial Artery Occlusion

To investigate the influence factors of hemorrhage and stroke with retriever with Solitaire AB stent in patients with acute intracranial artery occlusion.Methods:A retrospective of 43 cases of patients with acute intracranial artery occlusion for endovascular treatment with Solitaire AB stent enrolled from March 2016 to June 2018 in our hospital,combining the characteristics of the patients of our city,through the clinical baseline data statistical analysis,complications screening of risk factors of complications.Results:There were 81.4%of patients who were dredged totally.The incidences of cerebral hemorrhage and infarction were 18.6%and 16.3%,cerebral hemorrhage group compared with control group,diabetes,blood pressure,revascularized time,NIHSS score,ASPECTS score had statistically significant differences,when infarction group compared with control group,age,opening time,ASITN_SIR score and grade of mTICI had statistically significant differences.Conclusion:Mechanical thrombectomy with Solitaire AB stent in patients with acute intracranial artery occlusion,the occurred of complications associated with various clinical factors,and the occurrence of complications seriously affect the prognosis of patients,therefore,selecting the indications strictly,and adopt individualized treatment to reduce complications.

The impact of fundamental factors and sentiments on the valuation of cryptocurrencies

The valuation of cryptocurrencies is important given the increasing significance of this potential asset class.However,most state-of-the-art cryptocurrency valuation methods only focus on one of the fundamental factors or sentiments and use out-of-date data sources.In this study,a robust cryptocurrency valuation method is developed using up-to-date datasets.Using various panel regression models and moving-window regression tests,the impacts of fundamental factors and sentiments in the valuation of cryptocurrencies are explored with data covering from January 1,2009 to April 30,2023.The research shows the importance of sentiments and suggests that the fear and greed index can indicate when to make a cryptocurrency investment,while Google search interest in cryptocurrency is crucial when choosing the appropriate type of cryptocurrency.Moreover,consensus mechanism and initial coin offering have significant effects on cryptocurrencies without stablecoins,while their impacts on cryptocurrencies with stablecoins are insignificant.Other fundamental factors,such as the type of supply and the presence of smart contracts,do not have a significant influence on cryptocurrency.Findings from this study can enhance cryptocurrency marketisation and provide insightful guidance for investors,portfolio managers,and policymakers in assessing the utility level of each cryptocurrency.

A review of polybrominated diphenyl ethers and alternative brominated flame retardants in wildlife from China:Levels,trends,and bioaccumulation characteristics

Accelerated industrialization and urbanization,and unregulated disposal of waste of electric and electronic equipment（e-waste） in China have caused environmental pollution of brominated flame retardants（BFRs）.This review summarized the levels,trends,and bioaccumulation characteristics of polybrominated diphenyl ethers（PBDEs） and other potential alternative BFRs including hexabromocyclododecanes（HBCDs）,1,2-bis（2,4,6-dibromophenoxy） ethane（BTBPE） and decabromodiphenylethane（DBDPE） in wildlife from China.PBDE levels in wildlife from China were generally higher than those from other parts in Asia,and were comparable to those from Europe but were lower than those from North America.However,wildlife from the e-waste recycling sites in South China and East China contained much higher PBDEs compared to other reports around the world,suggesting the heavy contamination of PBDEs in these regions.The alternative BFRs were also detected in wildlife,revealing that the animals are exposed to these chemicals,in addition to PBDEs.Temporal trends indicated by levels in marine mammals from South China suggested that PBDE levels increased from the beginning of 1990s to 2000s,but decreased from the middle of 2000s,followed by relatively steady levels.In contrast,HBCDs were found to be continuously increasing from 1997 to 2007,indicating the increasing usage of HBCDs in China in recent years.Compared to PBDE profiles found in other parts,aquatic species and birds from China contained relatively higher contributions of BDE28 and 209,respectively,suggesting the possible different usage pattern of PBDEs.Future works including keeping monitoring at a reasonable scale and frequency to make sure levels near urban centers indicative of population do not increase are needed.Additionally,focus effort on e-waste recycling regions to look for impacts and to determine if regulation/controls are resulting in lower environmental contamination,and incorporation of sentinel species in monitoring efforts are recommended.

The leaching of additive-derived flame retardants(FRs) from plastics in avian digestive fluids:The significant risk of highly lipophilic FRs

The exposure to plastic debris and associated pollutants for wildlife is of urgent concern,but little attention has been paid on the transfer of plastic additives from plastic debris to organisms.In the present study,the leaching of incorporated flame retardants (FRs),including polybrominated diphenyl ethers (PBDEs),alternative brominated FRs (AFRs),and phosphate flame retardants (PFRs),from different sizes of recycled acrylonitrile-butadiene-styrene (ABS) polymer were investigated in avian digestive fluids.The impact of co-ingested sediment on the leaching of additive-derived FRs in digestive fluids was also explored.In the recycled ABS,BDE 209 (715 μg/g) and 1,2-bis(2,4,6-tribromophenoxy) ethane (BTBPE,1766 μg/g) had the highest concentrations among all target FRs.The leaching proportions of FRs were higher in finer sizes of ABS.The leaching proportions of FRs from recycled ABS increased with elevated logKow of FRs.In the tests with coexisted ABS and sediment,hexato deca-BDEs,BTBPE,and decabromodiphenyl ethane (DBDPE) migrated from ABS to sediment,which resulted in the less bioaccessible fractions of these FRs in gut fluids.More lipophilic chemicals tended to be adsorbed by sediment from ABS.The results suggest the migration of additive-derived FRs from plastics to other indigestible materials in digestive fluids.The findings in this study provide insights into the transfer of additive-derived FRs from plastics to birds,and indicate the significant contribution of FR-incorporated plastics to bioaccumulation of highly lipophilic FRs.