High Performance of Fly Ash Derived Li ₄SiO₄-Based Sorbents for High Temperature CO₂Capture

It is urgent to develop excellent solid CO2 sorbents with higher sorption capacity, simpler synthetic process, better thermal stability and lower costs of synthesis in CO2 capture and storage technologies. In this work, a number of Li4SiO4-based sorbents synthesized by lithium carbonate with three different kinds of fly ashes in various molar ratios were developed. The results indicate that the Li2CO3:SiO2 mole ratio used in the sorbents synthesis significantly affects the CO2 absorption properties. The sorption capacity increased with the excess of Li2CO3 first and then decreased when the excessive quantity was beyond a certain amount. The experiments found that FA-Li4SiO4_0.6, CFA-Li4SiO4_0.4, HCl/CFA-Li4SiO4_0.3 presented the best sorption ability among these fly ash derived Li4SiO4 samples, and the corresponding weight gain was 28.2 wt%, 25.1 wt% and 32.5 wt%, respectively. The three sorbents with the optimal molar ratio were characterized using various morphological characterization techniques and evaluated by thermogravimetric analysis for their capacity to chemisorb CO2 at 450°C - 650°C, diluted CO2 (10%, 20%) and in presence of water vapor (12%). The adsorption curve of FA- Li4SiO4_0.6 at different temperatures was simulated with the Jander-Zhang model to explore the influence of carbon dioxide diffusion on adsorption reaction. Further experiments showed that the adsorbent had a good sorption capacity in a lower partial pressure of CO2 and the presence of steam enhanced the mobility of Li+. What’s more, FA-Li4SiO4_0.6, CFA-Li4SiO4_0.4 and HCl/CFA-Li4SiO4_0.3 particles showed satisfactory sorption capacity in fixed-bed reactor and excellent cyclic sorption stability during 10 sorption/ desorption cycles.

Erucic acid from Isatis indigotica Fort. suppresses influenza A virus replication and inflammation in vitro and in vivo through modulation of NF-kB and p38 MAPK pathway

Isatis indigotica Fort.(Ban-Lan-Gen)is an herbal medicine prescribed for influenza treatment.However,its active components and mode of action remain mostly unknown.In the present study,erucic acid was isolated from Isatis indigotica Fort.,and subsequently its underlying mechanism against influenza A virus(IAV)infection was investigated in vitro and in vivo.Our results demonstrated that erucic acid exhibited broad-spectrum antiviral activity against IAV resulting from reduction of viral polymerase transcription activity.Erucic acid was found to exert inhibitory effects on IAV or viral(v)RNA-induced pro-inflam-matory mediators as well as interferons(IFNs).The molecular mechanism by which erucic acid with antiviral and anti-inflammatory properties was attributed to inactivation of NF-kB and p38 MAPK signaling.Furthermore,the NF-kB and p38 MAPK inhibitory effect of erucic acid led to diminishing the transcriptional activity of interferon-stimulated gene factor 3(ISGF-3),and thereby reducing IAV-triggered pro-inflammatory response amplification in IFN-β-sensitized cells.Additionally,IAV-or vRNA-triggered apoptosis of alveolar epithelial A549 cells was prevented by erucic acid.In vivo,erucic acid administration consistently displayed decreased lung viral load and viral antigens expression.Meanwhile,erucic acid markedly reduced CD8+cytotoxic T lymphocyte(CTL)recruitment,pro-apoptotic signaling,hyperactivity of multiple signaling pathways,and exacerbated immune inflammation in the lung,which resulted in decreased lung injury and mortality in mice with a mouse-adapted A/FM/1/47-MA(H1N1)strain infection.Our findings provided a mechanistic basis for the action of erucic acid against IAV-mediated inflammation and injury,suggesting that erucic acid may have a therapeutic potential in the treatment of influenza.

Interference-Free Pilot Design and Channel Estimation Using ZCZ Sequences for MIMO-OFDM-Based C-V2X Communications

Cellular vehicle-to-everything(C-V2X) communications is regarded as a promising and feasible solution for 5G-enabled vehicular communications and networking. In this paper, we investigate the pilot design and channel estimation problem in MIMO-OFDM-based C-V2X systems with severe co-channel interference due to spectrum reusing among different V2X communication links. By using zero-correlation zone(ZCZ) sequences, we provide an interference-free pilot design scheme and a corresponding time-domain(TD) correlation-based channel estimation(TD-CCE) method. We employ the ZCZ sequences from the same family set to be designed as the TD pilot symbols and guarantee the pilot sequeneces for neighboring V2X communication links are code-division multiplexing(CDM). The co-channel pilot interference of the deisgned pilot symbols can be effectively eliminated by exploiting the provided TD-CCE method. Simulation results indicate that the accuracy of channel estimation can be effectively improved by the proposed scheme, whose performance is close to that of the non-interference situation.

Gynecology and Gynecological Nursing Theories and Practices in Traditional Chinese Medicine: Review on the Ancient Literatures

Objective: the study is aimed to introduce the developing history of gynecology and gynecological nursing in traditional Chinese medicine (TCM). Study Design: the development of gynecology and gynecological nursing consists of six periods in Chinese history. They are: 1) budding stage represented by the inscriptions of Nü (female) on oracle bones;2) physiological development stages of women;3) specialized chapters of gynecology in TCM;4) features of gynecological nursing;5) monograph of gynecology and gynecological nursing;6) integration of ancient gynecological nursing perceptions. Results: TCM has a profound understanding of gynecology and gynecological nursing. For period one, the inscriptions of Nü (female) on oracle bones is the symbol of the budding stage. For period two, physiogenesis stages of women are recorded in The Yellow Emperor of Classics of Inner Medicine. For period three, the specialized chapters of gynecology appeared, represented by Golden Chamber, Woman. For period four, the features of gynecological nursing were elaborated in Essential Prescriptions Worth A Thousand Gold including menstruation, depression, yin-dampness, and menopause. For period five, monographs of gynecology and gynecological nursing represented by Good Comprehensive Woman Formulae appeared. For period six, Integrative studies of gynecological nursing perceptions were carried out with the representation by Integrated Ancient and Modern Books. Conclusion: TCM gynecology and gynecological nursing harbors a long history of treating and nursing gynecological disorders. With therapeutic and nursing modalities, they are effective systems of un-derstanding and managing woman health as proven by medical literatures, clinical benefits and basic research studies.

Introduction on the Emotion-Will Overcoming Therapy (EWOT): A Novel Alternative Approach of Psychological Treatment from Chinese Medicine

Emotional disorders and mental illnesses constitute a significant part of diseases. In Chinese medicine, emotional disorders and mental illnesses are classified as emotion-will (Qing Zhi) disorders. Emotion-will, i.e. seven emotions (Qi Qing: happiness, anger, anxiety, pensiveness, sorrow, fear, and fright) and five wills (Wu Zhi: happiness, anger, thinking, sorrow, and fear), play a basic role in the onset, progress and prognosis of almost all diseases, not only the mental illnesses. The emotion-will overcoming therapy (EWOT) is defined as a psychological approach that a therapist employs single or multiple emotions to overcome and eliminate patients’ abnormal morbid emotions and to heal mind-body disorders derived from the abnormality. EWOT lays a foundation for the philosophical foundation of Chinese medicine, i.e. Yin and Yang, and five elements, which is believed to be the most commonly utilized and effective modality in dealing with mental illnesses. This essay covers the origin and development, underlying mechanism, clinical application, basic researches of emotion-will system and EWOT and the comparison with conventional therapies. Thus, EWOT could draw more attention in the field of psychology and spread in clinical practice.

产教融合视域下专业课程思政一体化建设的实践探索

针对传统医学检验技术专业课程教学实施过程中存在的“课堂知识与临床实践链条脱节”“思政教育融入医学课堂不足”两大痛点问题,基于国家级现代产业学院产教融合建设和立德铸魂深化“三全育人”教育背景下,该教研组针对痛点问题进行教学改革,按照临床检验科工作流程重构知识体系深化产教融合,深挖课程思政元素实现德育渗透并贯穿于教与学全过程。以临床基础检验技术课程为例,总结了在产教融合背景下专业教育与课程思政一体化建设的教学实践。以期通过加强交流,在产教融合育人模式下更好地促进专业育才与思政育人的深度融合。

慢性乙型肝炎患者转氨酶与外周血中髓源性抑制细胞的关系研究

目的探讨慢性乙型肝炎(CHB)患者外周血中髓源性抑制细胞(MDSCs)的频率及MDSCs与肝功能、慢性乙型肝炎病毒(HBV)感染之间的相关性。方法选择2019年3月至2019年10月于广州市第一人民医院住院或门诊就诊且未接受抗病毒治疗的30例CHB患者作为CHB患者组,同时选取同一时间段的14名健康体检者作为健康对照组。分别采用流式细胞仪(FCM)检测CHB患者组和健康对照组患者的外周血单个核细胞(PBMCs)中MDSCs的频率,对两组MDSCs频率的差异进行了组间t检验比较分析。分别用干化学法和全自动生化分析仪测定两组血清谷丙转氨酶(ALT)和谷草转氨酶(AST);采用聚合酶链式反应(PCR)对两组HBV-DNA载量进行检测。Spearman相关分析MDSCs与HBV-DNA载量、ALT和AST的相关性。结果CHB患者组的MDSCs频率(2.347%)高于健康对照组(0.929%),差异有统计学意义(P=0.002)。CHB患者HBeAg阳性组和阴性组的MDSCs频率比较,差异无统计学意义(P=0.170)。CHB患者MDSCs频率与ALT、AST呈负相关(r=-0.319、r=-0.214,均P<0.05),但MDSCs频率与HBV-DNA载量无相关性(r=-0.154,P=0.742)。结论CHB患者组MDSCs频率高于健康对照组,且与ALT、AST呈负相关,提示MDSCs在CHB患者外周血中募集增多,可能与CHB感染的慢性炎症相关。