Early diagnosis and treatment of cancer requires the development of tools that are both sensitive and selective in detecting spermine.In this study,we presented a"supramolecular cyclization-induced emission enhan...Early diagnosis and treatment of cancer requires the development of tools that are both sensitive and selective in detecting spermine.In this study,we presented a"supramolecular cyclization-induced emission enhancement"strategy for the sensitive and selective detection of spermine.A new pillar[5]arene probe(P1)demonstrated excellent solution/solid dual-state emission properties,and the addition of certain spermine(Spm)resulted in fluorescence enhancement due to the synergy of multiple weak interactions that restricted the free motion of P1 in the P1⊃Spm complex.This mechanism was further confirmed by time-resolved spectroscopy,DFT calculations,and IGM analysis.With its low limit of detection and high selectivity,P1 is a promising tool for measuring spermine in artificial urine samples.展开更多
Summary of main observation and conclusion Selective oxidative C-H sulfenylation of imidazopyridine heterocycles is achieved using an undivided electrolytic cell.The reaction avoids the use of stoichiometric amount of...Summary of main observation and conclusion Selective oxidative C-H sulfenylation of imidazopyridine heterocycles is achieved using an undivided electrolytic cell.The reaction avoids the use of stoichiometric amount of external chemical oxidant and produces hydrogen gas as the only byproduct. Both aryl and aliphatic thiols demonstrate good reactivity for C-S bond formation.展开更多
The recycling reverse osmosis(RO)membrane concentrate of some high-ammonia nitrogen(NH_(4)^(+)-N)organic wastewater to the biological unit could cause potassium ion(K^(+))accumulation,thereby affecting the removal of ...The recycling reverse osmosis(RO)membrane concentrate of some high-ammonia nitrogen(NH_(4)^(+)-N)organic wastewater to the biological unit could cause potassium ion(K^(+))accumulation,thereby affecting the removal of NH_(4)^(+)-N by activated sludge.Thus,the effects of high K^(+) stress on activated sludge nitrification performance was studied.The results showed that the high K^(+) stress promoted the floc sludge to produce more extracellular polymers(EPS),which accelerated the sludge sedimentation and enriched the biomass in sequential batch reactors(SBRs).The ammonia oxidation process and nitrite(NO_(2)^(-)-N)oxidation process were further analyzed in the nitrification process.High K^(+) stress enriched ammonia oxidizing bacteria(AOB),which ensured the efficient ammonia oxidation process in SBRs,and ensured the removal rate of NH_(4)^(+)-N was maintained above 93%.However,high K^(+) stress(15g/L KCl)inhibited the activity of NO_(2)^(-)-N oxidizing bacteria(NOB)and reduced the abundance of NOB,thus leading to the accumulation of NO_(2)^(-)-N,and finally worsened the nitrification performance of activated sludge.In short,the performance of activated sludge will not be inhibited when the K^(+) in the wastewater does not exceed 5.23 g/L.The results could provide a reference for the optimization of the biological performance in treating high-NH_(4)^(+)-N organic wastewater with activated sludge coupled RO membrane treatment process.展开更多
基金the National Natural Science Foundation of China(Nos.22071066,22071065)the National Key Research and Development Program of China(No.2016YFA0602900)+1 种基金the Guangdong Natural Science Foundation,China(No.2018B030311008)the Guangzhou Science and Technology Project,China(No.202102020802).
文摘Early diagnosis and treatment of cancer requires the development of tools that are both sensitive and selective in detecting spermine.In this study,we presented a"supramolecular cyclization-induced emission enhancement"strategy for the sensitive and selective detection of spermine.A new pillar[5]arene probe(P1)demonstrated excellent solution/solid dual-state emission properties,and the addition of certain spermine(Spm)resulted in fluorescence enhancement due to the synergy of multiple weak interactions that restricted the free motion of P1 in the P1⊃Spm complex.This mechanism was further confirmed by time-resolved spectroscopy,DFT calculations,and IGM analysis.With its low limit of detection and high selectivity,P1 is a promising tool for measuring spermine in artificial urine samples.
基金the National Natural Science Foundation of China (21390402,21520102003)the Hubei Province Natural Science Foundation of China (2017CFA010)The Program of Introducing Talents of Discipline to Universities of China (111 Program)was also appreciated.
文摘Summary of main observation and conclusion Selective oxidative C-H sulfenylation of imidazopyridine heterocycles is achieved using an undivided electrolytic cell.The reaction avoids the use of stoichiometric amount of external chemical oxidant and produces hydrogen gas as the only byproduct. Both aryl and aliphatic thiols demonstrate good reactivity for C-S bond formation.
基金supported by the Sichuan Science&Technology Program(No.2020YFS0438)the National Natural Science Foundation of China(No.31971386)+1 种基金the China Agriculture Research System(No.CARS-35)the Fundamental Research Funds for Central Non-profit Scientific Institution(No.2060302-022-21-016)。
文摘The recycling reverse osmosis(RO)membrane concentrate of some high-ammonia nitrogen(NH_(4)^(+)-N)organic wastewater to the biological unit could cause potassium ion(K^(+))accumulation,thereby affecting the removal of NH_(4)^(+)-N by activated sludge.Thus,the effects of high K^(+) stress on activated sludge nitrification performance was studied.The results showed that the high K^(+) stress promoted the floc sludge to produce more extracellular polymers(EPS),which accelerated the sludge sedimentation and enriched the biomass in sequential batch reactors(SBRs).The ammonia oxidation process and nitrite(NO_(2)^(-)-N)oxidation process were further analyzed in the nitrification process.High K^(+) stress enriched ammonia oxidizing bacteria(AOB),which ensured the efficient ammonia oxidation process in SBRs,and ensured the removal rate of NH_(4)^(+)-N was maintained above 93%.However,high K^(+) stress(15g/L KCl)inhibited the activity of NO_(2)^(-)-N oxidizing bacteria(NOB)and reduced the abundance of NOB,thus leading to the accumulation of NO_(2)^(-)-N,and finally worsened the nitrification performance of activated sludge.In short,the performance of activated sludge will not be inhibited when the K^(+) in the wastewater does not exceed 5.23 g/L.The results could provide a reference for the optimization of the biological performance in treating high-NH_(4)^(+)-N organic wastewater with activated sludge coupled RO membrane treatment process.
