Prelithiation Enhances Cycling Life of Lithium-Ion Batteries:A Mini Review

During the last decade,the rapid development of lithium-ion battery(LIB)energy storage systems has provided significant support for the efficient operation of renewable energy stations.In the coming years,the service life demand of energy storage systems will be further increased to 30 years from the current 20 years on the basis of the equivalent service life of renewable energy stations.However,the life of the present LIB is far from meeting such high demand.Therefore,research on the next-generation LIB with ultra-long service life is imminent.Prelithiation technology has been widely studied as an important means to compensate for the initial coulombic efficiency loss and improve the service life of LIBs.This review systematically summarized the different prelithiation methods from anode and cathode electrodes.Moreover,the large-scale industrialization challenge and the possibility of the existing prelithiation technology are analyzed,based on three key parameters:industry compatibility,prelithiation efficiency,and energy density.Finally,the future trends of improvement in LIB performance by other overlithiated cathode materials are presented,which gives a reference for subsequent research.

Development of Yimeng Red Tourism Resources from the Perspective of Tourist Perception

In this paper,the connotation of red tourism is explained from a new perspective firstly.On the basis of summarizing and evaluating the red tourism resources in Yimeng,combined with the current development status of red tourism in Yimeng region,based on the subjective evaluation of tourists on the development of red tourism in Yimeng region,several targeted suggestions for the development of red tourism in Yimeng are proposed.

Effect of Nursing Intervention Based on Caprini Risk Assessment Scale for Venous Thromboembolism in Perioperative Patients with Liver Cancer

Objective:To explore the effect of nursing intervention based on Caprini risk assessment scale for venous thromboembolism(VTE)in perioperative patients with liver cancer.Methods:A total of 128 hepatocellular cancer(HCC)patients who were hospitalized in our department from January 2021 to March 2022 and met the research criteria were selected.According to odd and even numbers in the order of inclusion,64 cases were divided into two groups:a control group and an observation group.The control group received routine nursing intervention during perioperative period,while the observation group received nursing intervention based on Caprini risk assessment scale for VTE.The incidence of VTE and complications were compared between the two groups.Results:The incidence of VTE and postoperative complications in the observation group were lower than those in the control group(P<0.05).Conclusion:Nursing intervention based on Caprini risk assessment scale for VTE can reduce the incidence of perioperative deep vein thrombosis and complications in patients with liver cancer;thus,it is worthy of clinical application.

Do They Pose a Danger:Evaluation of the Recidivism Characteristics in China’s Community Corrections?

The modern criminal justice system includes community corrections,which play a preventive role in lowering recidivism among offenders.However,some offenders continue to commit crimes during community corrections.This research focuses on community corrections in Chinese community policing practice,particularly offender recidivism.The study collected a total of 500 questionnaires from offenders in the provincial administrative regions of northern China,which included first offense status,psychological status,and recidivism behavior.The study found that most recidivists are usually arrested for“drunk driving”,which may be related to their ability to exercise self-restraint,and that alcohol may contribute to their deviant behavior.Another important finding relates to young recidivists,who may have difficulty securing employment during community corrections and thus use crime again to gain income.In general,this study explores the offender population in Chinese community corrections practice and discusses the factors within it that influence offender recidivism.This may support law enforcement agencies in further evaluating the effectiveness of community corrections,and may provide new information for understanding community corrections in China.

Application Effect of Medium-Length Peripheral Catheter in Critically Ill Patients Undergoing Hepatobiliary Surgery

Objective:To investigate the effect of using peripheral medium-length catheters in critically ill patients undergoing hepatobiliary surgery.Methods:A retrospective analysis of the nursing experience and effect of using medium-length catheters for infusion in 102 critically ill patients undergoing hepatobiliary surgery from March 2021 to April 2022 was conducted.Results:All 102 patients had successful catheter placement with no catheter-associated infections,blockage,decannulation,or breakage.However,four cases had blood oozing from the puncture site,but it resolved after changing the dressing.Conclusion:Medium-length catheters are superior to traditional infusion tools in terms of benefit;thus,they deserve to be widely promoted in clinical practice.

Overexpression of C-terminal fragment of glutamate receptor 6 prevents neuronal injury in kainate-induced seizure via disassembly of Glu R6-PSD95-MLK3 signaling module

Our previous study showed that when glutamate receptor （GluR）6 C terminus-containing peptide conjugated with the human immunodeficiency virus Tat protein （GluR6）-9c is delivered into hippocampal neurons in a brain ischemic model, the activation of mixed lineage kinase 3 （MLK3） and c-Jun NH2-terminal kinase （JNK） is inhibited via GluR6-postsynaptic density protein 95 （PSD95）. In the present study, we investigated whether the recombinant adenovirus （Ad） carrying GluR6c could suppress the assembly of the GluR6-PSD95-MLK3 signaling module and decrease neuronal cell death induced by kainate in hippocampal CA1 subregion. A seizure model in Sprague-Dawley rats was induced by intraperitoneal injections of kainate. The effect of Ad- Glur6-9c on the phosphorylation of INK, MLK3 and mitogen-activated ldnase kinase 7 （MKK7） was observed with western immunoblots and immunohistochemistry. Our findings revealed that overexpression of GluR6c inhibited the interaction of GluR6 with PSD95 and prevented the kainate-induced activation of INK, MLK3 and MKK7. Furthermore, kainate-mediated neuronal cell death was significantly suppressed by GluR6c. Taken together, GluR6 may play a pivotal role in neuronal cell death.

Biochar-mediated regulation of greenhouse gas emission and toxicity reduction in bioremediation of organophosphorus pesticide-contaminated soils

Organophosphorus pesticides(OPPs) are a set of toxic persistent organic pollutants(POPs) present in the environment. Recently, biochar-mediated bioremediation has exhibited many advantages over conventional methods for the remediation of pesticide-contaminated soil. In the present study, biochar and nitrogen fertilizer(NH_4NO_3)were employed to remediate OPP-contaminated soil and the greenhouse gas(GHG) emission during 90 days of incubation was investigated. After thermal desorption treatment, the content of organophosphorus pesticides reduced from 175.61 μg·kg^(-1) to 62.68 μg·kg^(-1). The addition of NH_4NO_3 in the following bioremediation led to larger reduction(34.35%) of the pesticide concentration than that of biochar(31.90%) for the contaminated soils with thermal desorption treatment, while the simultaneous addition of biochar and NH_4NO_3 led to the largest reduction of pesticide concentration(11.07%) for the soil without thermal desorption treatment. The addition of biochar and NH_4NO_3 only slightly increased the emission rate of GHGs from the soil without thermal treatment,but remarkably increased the emission rate of GHGs from the soil after thermal treatment. In most cases, the addition of NH_4NO_3 is more effective than biochar to promote the degradation of pesticide, but also exhibited higher GHG emission. The microbial community analysis suggests that the enhanced degradation of pesticide is mainly owing to the increased activity of microorganism.

Research on fractal characteristics of primary phase morphology in semi-solid A356 alloy

Semi-solid slurry of A356 alloy was prepared by low superheat pouring and slightly electromagnetic stirring, and the fractal characteristics of morphology in semi-solid primary phase was researched. The fractal dimensions of primary phase morphology in the semi-solid A356 alloy were calculated by the program written to calculate the fractal dimensions of box-counting in the image of solid phase morphology in semi-solid metal slurry. The results indicated that the morphology of primary phase in semi-solid A356 prepared by low superheat pouring and slightly electromagnetic stirring is characterized by fractal dimension, and the primary phase morphology obtained by the different processing parameters has different fractal dimensions. The morphology of primary phase at the different position of ingot has different fractal dimensions, which reflected the effect of solidified conditions at different positions in the same ingot on the morphology of semi-solid primary phase. Solidification of semi-solid alloy is a course of change in fractal dimension.

The Family of Exponential Attractors and Inertial Manifolds for a Generalized Nonlinear Kirchhoff Equations

In this paper, we study the long-time behavior of a class of generalized nonlinear Kichhoff equation under the condition of n dimension. Firstly, the Lipschitz property and squeezing property of the nonlinear semigroup related to the initial-boundary value problem are proved, and then the existence of its exponential attractor is obtained. By extending the space E0 to Ek, a family of the exponential attractors of the initial-boundary value problem is obtained. In the second part, we consider the long-time behavior for a system of generalized Kirchhoff type with strong damping terms. Using the Hadamard graph transformation method, we obtain the existence of a family of the inertial manifolds while such equations satisfy the spectrum interval condition.

Effect of Dihydrotestosterone on Costimulatory Molecules in a Mouse Model of Graves’ Disease

Objective Graves’disease is the most common autoimmune thyroid disease and its prevalence and clinical manifestations are disparate between females and males.Costimulatory molecules play an essential role in regulating autoimmune responses.The objective of this study was to determine if expression of inhibitory molecules was correlated with treatment by dihydrotestosterone(DHT)in an in vivo BALB/c mouse model of experimental autoimmune Graves’disease.Methods Female BALB/c mice were immunized three times with thyroid stimulating hormone receptor A-subunit encoded by adenovirus to establish a Graves’disease model.Three different doses of DHT or a matching placebo were administered by implantation of slow-release pellets a week before the first immunization.Four weeks after the third immunization,the mice were euthanatized,and then the spleen and thymus were removed.Total thyroxine and free thyroxine levels in serum of mice were detected using a radioimmunoassay kit.Real-time polymerase chain reaction was performed to estimate the expression of costimulatory molecules in lymphocytes from the spleen and thymus.Flow cytometry was used to analyze the percentage of CD4^+T cells in splenic lymphocytes.Quantitative data were compared with unpaired t-tests.Correlation between two variables was analyzed using Analysis of Variance.Results Treatment with DHT can dramatically reduce total thyroxine and free thyroxine levels.Higher expression of programmed death-1 was found in the spleen of Graves’disease mice receiving 5 mg of DHT treatment(0.635±0.296 vs.0.327±0.212;t=2.714,P=0.014),similarly,T-cell immunoglobulin domain and mucin domain 3(TIM-3)in both the spleen(1.004±0.338 vs.0.646±0.314;t=2.205,P=0.022)and the thymus(0.263±0.127 vs.0.120±0.076;t=3.221,P=0.004)also increased after 5 mg of DHT treatment compared with the parallel placebo model mice.Moreover,the percentage of CD4^+T cells declined in the splenic lymphocytes of Graves’disease mice treated with 5 mg of DHT(19.90%±3.985%vs.24.05%±2.587%;t=2.804,P=0.012).A significant negative association was observed between expression of TIM-3 in the spleen and serum levels of total thyroxine(r=-0.7106,P=0.014)as well as free thyroxine(r=-0.6542,P=0.029).Conclusion This study demonstrates that DHT can ameliorate experimental autoimmune Graves’disease,which may occur by up-regulating expression of programmed death-1 and TIM-3 and inhibiting development of CD4^+T cells.

Exploration on the Value and Path of Red Tourism Integrated into Ideological and Political Courses in Colleges and Universities

The state has issued a series of policy documents to vigorously promote the construction and development of ideological and political courses in colleges and universities.Red tourism provides a broader vision and deeper meaning for deepening the educational function of ideological and political courses.Using research methods such as literature research and case analysis,the restrictive factors that affect the effect of ideological and political education are discussed,and new ideas and new ways are put forward,such as promoting the synchronous construction of the first classroom and the second classroom of ideological and political courses,and integrating the small classroom of ideological and political education into the large classroom of society.The research could provide useful reference for the deepening development of red tourism in the new era and the multi-dimensional expansion of ideological and political courses in colleges and universities.

Effectiveness of Rain Classroom Intelligent Teaching Design : A Case Study of the Course of Spring Water Tourism Resources

[Objectives]To evaluate the effectiveness of Rain Classroom intelligent teaching in the course of Spring Water Tourism Resources.[Methods]The course of Spring Water Tourism Resources in the course of Overview of Tourism Resources was taken as an example,the pre-class preparation,in-class teaching,and after-class evaluation links were designed separately through the Rain Classroom platform.Then,a questionnaire survey was carried out for the students of Spring Water Tourism Resources.[Results]About 58.3%of the students believed that the greatest advantage of using the Rain Classroom teaching platform is that the learning method is flexible and can improve the ability of independent learning;61.78%of students stated that playing 3D animation in the classroom has the best effect for learning different tourism resources;with the aid of the Rain Classroom platform,the communication between teachers and students becomes more timely,and the students' ability to deal with practical problems can be practiced.[Conclusions]This study is intended to build an intelligent classroom model suitable for tourism management department based on the Rain Classroom platform.It is recommended to promote and apply this model in the teaching of tourism management.

Teaching Design of Tourism Management Based on Information-based Teaching Method:A Case Study of Selection of Hotel Construction Site

Taking the knowledge points of hotel construction site selection as an example,this paper integrated the information-based teaching method with traditional classrooms.With the aid of virtual reality(VR)technology,the information-based teaching can turn the abstract knowledge into vivid knowledge.Using the Rain Classroom platform,teachers can communicate with students in a better manner.Combined with the powerful spatial data analysis function of geographic information system(GIS)software,it is intended to provide new ideas and perspectives for the effective integration of traditional teaching classrooms and information technology,and effectively apply them to the practical teaching process.

Research on Evaluation and Development of Industrial Heritage Tourism Resources in Textile Valley

This paper selects Qingdao Textile Valley as the research object,establishes the evaluation system of industrial heritage tourism resources,and analyzes the evaluation factors of industrial heritage tourism resources,such as resource element value,market location value,and environmental factors.Then this paper puts forward some effective suggestions to promote the development of industrial heritage tourism in Textile Valley.The results show that the measures put forward,such as fully tapping the value of resource elements,improving the surrounding traffic environment,perfecting tourism signs,perfecting local traffic routes,improving the complementarity of tourism resources,and expanding the tourist market,can scientifically and effectively protect urban industrial heritage,improve the development level of urban tourism,and speed up the transformation of new and old energy in Qingdao.

A novel sprayable thermosensitive hydrogel coupled with zinc modified metformin promotes the healing of skin wound

A novel sprayable adhesive is established(ZnMet-PF127)by the combination of a thermosensitive hydrogel(Pluronic F127,PF127)and a coordination complex of zinc and metformin(ZnMet).Here we demonstrate that ZnMet-PF127 potently promotes the healing of traumatic skin defect and burn skin injury by promoting cell proliferation,angiogenesis,collagen formation.Furthermore,we find that ZnMet could inhibit reactive oxygen species(ROS)production through activation of autophagy,thereby protecting cell from oxidative stress induced damage and promoting healing of skin wound.ZnMet complex exerts better effects on promoting skin wound healing than ZnCl2 or metformin alone.ZnMet complex also displays excellent antibacterial activity against Staphylococcus aureus or Escherichia coli,which could reduce the incidence of skin wound infections.Collectively,we demonstrate that sprayable PF127 could be used as a new drug delivery system for treatment of skin injury.The advantages of this sprayable system are obvious:(1)It is convenient to use;(2)The hydrogel can cover irregular skin defect sites evenly in a liquid state.In combination with this system,we establish a novel sprayable adhesive(ZnMet-PF127)and demonstrate that it is a potential clinical treatment for traumatic skin defect and burn skin injury.

Four novel Z-shaped hexanuclear vanadium oxide clusters as efficient heterogeneous catalysts for cycloaddition of CO_(2) and oxidative desulfurization reactions

Chemical fixation of CO_(2)into C1 source, as a general approach, can effectively alleviate the emission of greenhouse gasses. Whereas, the challenge posed by the need for efficient catalysts with high catalytic active sites still exists. In this work, we reported a series of new hexavanadate clusters, [(C6H6ON)2(C2H8N2)2(CH3O)6VIV6O8](V6–1), [(C6H6ON)2(C3H10N2)2(CH3O)6VIV6O8](V6–2), [(C6H6ON)2(C6H14N2)2(CH3O)6VIV6O8](V6–3) and [(C6H6ON)2(C4H11N2O)2(CH3O)4VIV6O8](V6–4), assembled by 2-aminophenol and four different kinds of Lewis bases(LB), ethanediamine(en), 1,2-diaminopropane, 1,2-cyclohexanediamine and N-(2-hydroxyethyl)ethylenediamine(ben) together. Among them, the basic unit {V6} cluster featured Z-shaped configuration represents a brand-new example of hexanuclear vanadium clusters. Remarkably, the catalytic tests demonstrated that V6–1 as catalyst displays high catalytic activity in the cycloaddition for the CO_(2)fixation into cyclic carbonates by virtue of open V sites. As expected, for oxidative desulfurization of sulfides, V6–1 also exhibits satisfied catalytic effectiveness. Furthermore, the recycling test confirmed that catalyst V6–1 may be a bifunctional heterogeneous catalyst with great promise for both CO_(2)cycloaddition and oxidative desulfurization reactions.

G-quadruplexes folding mediates downregulation of PBX1 expression in melanoma

Dear Editor,Pre-B-cell leukemia homeobox transcription factor 1(PBX1)is identified at t(1;19)chromosomal translocations in acute pre-B-cell leukemia and is involved in regulating multiple biological processes.1 Importantly,accumulating evidence have suggested that dysregulation of PBX1 have been shown to be involved in tumorigenesis,poor prognosis and drug resistance.1 It has been shown that the expression of PBX1 is increased in melanoma cells and overexpression of PBX1 significantly promotes the melanoma cell growth.

Detection method of absence seizures based on Resnet and bidirectional GRU

Background Epilepsy is a common chronic neurological disease.Its repeated seizure attacks have a great negative impact on patients’physical and mental health.The diagnosis of epilepsy mainly depends on electroencephalogram(EEG)signals detection and analysis.There are two main EEG signals detection methods for epilepsy.One is the detection based on abnormal waveform,the other is the analysis of EEG signals based on the traditional machine learning.The feature extraction method of the traditional machine learning is difcult to capture the high-dimension information between adjacent sequences.Methods In this paper,redundant information was removed from the data by Gaussian fltering,downsampling,and short-time Fourier transform.Convolutional Neural Networks(CNN)was used to extract the high-dimensional features of the preprocessed data,and then Gate Recurrent Unit(GRU)was used to combine the sequence information before and after,to fully integrate the adjacent information EEG signals and improve the accuracy of the model detection.Results Four models were designed and compared.The experimental results showed that the prediction model based on deep residual network and bidirectional GRU had the best efect,and the test accuracy of the absence epilepsy test set reached 92%.Conclusions The prediction time of the network is only 10 sec when predicting four-hour EEG signals.It can be efectively used in EEG software to provide reference for doctors in EEG analysis and save doctors’time,which has great practical value.

Optimal control for a class of impulsive switched systems

In this paper,an optimal switch-time control problem is solved for a class of impulsive switched autonomous systems.The considered systems jump at the switching times,and the sequence of active subsystems is pre-specified.The control variables consist of the impulse times and a set of scalars which determine the jump amplitudes.Moreover,the subsystems do not require a refractory period,which can bring more generality.Using the calculus of variation,the partial derivatives of the cost with respect to the control variables are derived,based on which the optimality conditions are given.Meanwhile,the obtained formulas can be used in some gradient descent algorithms to locate the optimal control variables.Finally,the viability of the proposed method is illustrated through two numerical examples.

2007-2018年浙江省义乌市新生儿出生体重变化趋势比较分析

目的分析2007-2018年浙江省义乌市新生儿出生体重变化趋势,并与不同标准进行比较,制订和更新适合目标人群的新生儿出生体重曲线。方法利用义乌市妇幼保健信息平台的数据,提取2007年1月至2018年6月记录的新生儿出生体重,分析出生体重变化趋势以及低出生体重儿和巨大儿发生率变化情况。采用LMS方法计算出胎龄别出生体重百分位数参考值,运用GAMLSS模型绘制出生体重曲线;将本研究的胎龄别出生体重百分位数参考值与国内外研究进行对比。结果本研究共纳入了68 358名新生儿,其中男、女婴的平均出生体重分别为3 373 g和3 257 g。男、女婴早产的比例分别为6.01%和5.04%,男婴早产比例显著高于女婴。低出生体重儿和巨大儿分别占3.84%和7.43%。出生胎龄33~41周的男婴出生体重均显著大于女婴出生体重。随着出生胎龄的增长,出生体重也相应增加。男婴出生胎龄为37~41周的胎龄别出生体重均大于2015年全国标准;33~41周的胎龄别出生体重均大于INTERGROWTH-21st的百分位数参考值。女婴出生胎龄为38~41周的胎龄别出生体重均大于2015年全国标准;33、35~41周的胎龄别出生体重均大于INTERGROWTH-21st的百分位数参考值。结论 2007-2018年义乌市男婴出生体重呈逐年下降趋势,女婴出生体重随年份变化趋势不显著。本次研究提出了义乌市新生儿胎龄别出生体重参考值,分性别绘制了出生体重曲线参考。