Rock failure can cause serious geological disasters,and the non-extensive statistical features of electric potential(EP)are expected to provide valuable information for disaster prediction.In this paper,the uniaxial c...Rock failure can cause serious geological disasters,and the non-extensive statistical features of electric potential(EP)are expected to provide valuable information for disaster prediction.In this paper,the uniaxial compression experiments with EP monitoring were carried out on fine sandstone,marble and granite samples under four displacement rates.The Tsallis entropy q value of EPs is used to analyze the selforganization evolution of rock failure.Then the influence of displacement rate and rock type on q value are explored by mineral structure and fracture modes.A self-organized critical prediction method with q value is proposed.The results show that the probability density function(PDF)of EPs follows the q-Gaussian distribution.The displacement rate is positively correlated with q value.With the displacement rate increasing,the fracture mode changes,the damage degree intensifies,and the microcrack network becomes denser.The influence of rock type on q value is related to the burst intensity of energy release and the crack fracture mode.The q value of EPs can be used as an effective prediction index for rock failure like b value of acoustic emission(AE).The results provide useful reference and method for the monitoring and early warning of geological disasters.展开更多
Effective monitoring of the structural health of combined coal-rock under complex geological conditions by pressure stimulated currents(PSCs)has great potential for the understanding of dynamic disasters in undergroun...Effective monitoring of the structural health of combined coal-rock under complex geological conditions by pressure stimulated currents(PSCs)has great potential for the understanding of dynamic disasters in underground engineering.To reveal the effect of this way,the uniaxial compression experiments with PSC monitoring were conducted on three types of coal-rock combination samples with different strength combinations.The mechanism explanation of PSCs are investigated by resistivity test,atomic force microscopy(AFM)and computed tomography(CT)methods,and a PSC flow model based on progressive failure process is proposed.The influence of strength combinations on PSCs in the progressive failure process are emphasized.The results show the PSC responses between rock part,coal part and the two components are different,which are affected by multi-scale fracture characteristics and electrical properties.As the rock strength decreases,the progressive failure process changes obviously with the influence range of interface constraint effect decreasing,resulting in the different responses of PSC strength and direction in different parts to fracture behaviors.The PSC flow model is initially validated by the relationship between the accumulated charges of different parts.The results are expected to provide a new reference and method for mining design and roadway quality assessment.展开更多
A complete spinal cord injury model was established in experimental rabbits using the spinal cord clip compression method. Urodynamic examination was performed 2 weeks later to determine neurogenic bladder status. The...A complete spinal cord injury model was established in experimental rabbits using the spinal cord clip compression method. Urodynamic examination was performed 2 weeks later to determine neurogenic bladder status. The rabbits were treated with anodal block stimulation at sacral anterior roots for 4 weeks. Electrical stimulation of sacral anterior roots improved urodynamic parameters of neurogenic bladder in rabbit models of complete spinal cord injury, effectively promoted urinary function, and relieved urinary retention. Immunohistochemistry results showed that a balance was achieved among expression of muscarinic receptor subunits M2, M3, ATP-gated ion channel P2X3 receptors, and 132-adrenergic receptor, and nerve growth factor expression decreased. These results suggested that long-term sacral anterior root stimulation of anodal block could'be used to treat neurogenic bladder in a rabbit model of complete spinal cord injury.展开更多
The sacral nerve anterior root consists of parasympathetic nerves(dominating urinary bladder detrusor)and somatic motor nerves(dominating urethral sphincter),and electrical stimulation to the sacral nerve anterior...The sacral nerve anterior root consists of parasympathetic nerves(dominating urinary bladder detrusor)and somatic motor nerves(dominating urethral sphincter),and electrical stimulation to the sacral nerve anterior root induces simultaneous contraction of the bladder detrusor and urethral sphincter.Accordingly,urethral pressure exceeds intravesical pressure,resulting in little or no urination,kidney damage,and trembling of lower limbs due to high intravesical pressure.In the present study,sacral nerve posterior roots were transected in a spastic bladder rabbit model,followed by three-pole electrode and long-pulse electrical stimulation to the sacral anterior root.Intravesical and urethral pressures were simultaneously measured to verify the feasibility of anode inhibition to the sacral anterior root following induced detrusor contraction.As stimulus intensity increased,somatic motor nerves were increasingly inhibited; with a stimulus pulse width of 300 μs and stimulus current of 1.05 mA,urethral pressure was zero and average intravesical pressure was 3.84 kPa.In addition,detrusor contraction was displayed,and lower extremity trembling was significantly reduced.Three-pole electrode and long-pulse electrical stimulation to the sacral nerve anterior root induced detrusor contraction and inhibited low extremity trembling under electrical stimulation.展开更多
Allelopathic autotoxicity occurs when a plant releases toxic chemical substances into the environment which inhibits development and growth of the same plant species.Rehmannia glutinosa L.( R.glutinosa ) is one of the...Allelopathic autotoxicity occurs when a plant releases toxic chemical substances into the environment which inhibits development and growth of the same plant species.Rehmannia glutinosa L.( R.glutinosa ) is one of the most common traditional Chinese medicines,whose productivity and quality,however,are seriously impacted by consecutive monoculture obstacle.Allelopathic autotoxicity is one reason for consecutive monoculture obstacle.In this paper,we reviewed the categories of allelochemicals,the methods of allelochemicals identification,and the mechanisms of allelopathic autotoxicity,which provides clues for further study of the molecular mechanisms of allelopathic autotoxicity and consecutive monoculture obstacle.展开更多
Rehmannia glutinosa L.is one of the important medicinal crops in China.Continuous cropping obstacle severely restricts the yield and quality of R.glutinosa,but its molecular mechanism is still unclear.In this study,wi...Rehmannia glutinosa L.is one of the important medicinal crops in China.Continuous cropping obstacle severely restricts the yield and quality of R.glutinosa,but its molecular mechanism is still unclear.In this study,with widely-planted "Wen 85-5" as an experiment material,based on the digital gene expression profiling (DGE) data of previous five stress treatments (continuous cropping,phenolic acid,salt,drought and waterlogging) and the first cropping and continuous cropping treatments of R.glutinosa in five different periods (seedling period,elongation period,early expanding period,middle expanding period and later expanding period),80 candidate genes (|log 2 ratio|≥1,FDR <0.001) specifically responding to continuous cropping obstacle in R.glutinosa were screened.Functional analysis revealed that the differentially expressed genes were involved in the secretion and endocytosis of root cells,which may suggest that the recognition and absorption of allelopathic autotoxins by the roots of R.glutinosa is an important factor that restricts the development of roots in continuous cropping of R.glutinosa.In order to accurately lock genes specifically responding to continuous cropping obstacle in R.glutinosa,continuous cropping soil extract and ferulic acid and p-hydroxybenzonic acid were used to treat aseptic plantlets of R.glutinosa,respectively,and it was confirmed through qRT-PCR that the expression levels of some genes under phenolic acid treatment changed more severely than that under the continuous cropping soil extract treatment,and four key genes involved in the response of R.glutinosa to continuous cropping were finally locked.This study lays a foundation for further exploration of the molecular mechanism of continuous cropping obstacle.展开更多
After investigating the current situation of college students'employment and entrepreneurship environment and the existing problems and related policies in the Beijing-Tianjin-Hebei region under the background of ...After investigating the current situation of college students'employment and entrepreneurship environment and the existing problems and related policies in the Beijing-Tianjin-Hebei region under the background of the integration of Beijing-Tianjin-Hebei region,this project put forward some insights into the reform of university teaching.First,a questionnaire survey was conducted to understand the basic information of the respondents,the obstacles to starting a business,and the current situation of the entrepreneurial environment such as government assistance.The questionnaires were distributed in the questionnaire star.The data were summarized with Excel;reliability and validity analysis was performed with SPSS,and descriptive statistical analysis was performed with Excel;and then,one-way ANOVA and exploratory factor analysis were performed with SPSS,and confirmatory factor analysis was performed with the SEM structural equation.It was found that gender,educational background and major have a significant impact on choosing to start a business.The evaluation indexes of entrepreneurial environment were divided into two common factors:government policy assistance and government fund assistance,and eight specific influencing factors were obtained,and the model fit well.This paper analyzed the work that schools have to do in the process of college students'entrepreneurship and its impact on entrepreneurship,providing ideas for the government and schools to help college students start their own businesses in the future.展开更多
The nominal Li_(3-x)Fe_(2-x)Ti_x(PO_4)_(2.55)(VO_4)_(0.45)(x=0~0.3) compounds were synthesized by a sol-gel process.Different from the single V043 doping, further introduction of Ti^(4+) ion was easy to result in pre...The nominal Li_(3-x)Fe_(2-x)Ti_x(PO_4)_(2.55)(VO_4)_(0.45)(x=0~0.3) compounds were synthesized by a sol-gel process.Different from the single V043 doping, further introduction of Ti^(4+) ion was easy to result in precipitation of a little secondary phases, besides the main NASICON products. The simultaneous substitution of Ti^(4+)and VO_4~3 for Fe^(3+) and PO_4~3,respectively, in the Li_3 Fe_2(PO_4)_3 resulted in a net improvement in the rate capability and cycling performance, as compared with the single Ti^(4+) or VO_4~3-substituted compound.The sample with x=0.2 presented a high initial discharging capacity of 125.4 mAh/g at the rate of 0.5 C,about 25% higher than the Ti^(4+)-substituted Li_(2.8)Fe_(1.8)Ti_(0.2)(PO_4)_3, and 102.6 mAh/g after 60 cycles at 2 C,about 12% higher than the single VO_4~3-substituted one. The high rate performance between 0.5 C to 10 C suggested that this sample had a good stability and reversibility. These results proved that the combination of the Ti^(4+) substitution for Fe^(3+) with the V043 substitution for PO_4~3 was a promising method of improving electrochemical performance of the studied Li_3 Fe_2(PO_4)_3 cathode material.展开更多
基金supported by National Key R&D Program of China(2022YFC3004705)the National Natural Science Foundation of China(Nos.52074280,52227901 and 52204249)+1 种基金the Postgraduate Research&Practice Innovation Program of Jiangsu Province(No.KYCX24_2913)the Graduate Innovation Program of China University of Mining and Technology(No.2024WLKXJ139).
文摘Rock failure can cause serious geological disasters,and the non-extensive statistical features of electric potential(EP)are expected to provide valuable information for disaster prediction.In this paper,the uniaxial compression experiments with EP monitoring were carried out on fine sandstone,marble and granite samples under four displacement rates.The Tsallis entropy q value of EPs is used to analyze the selforganization evolution of rock failure.Then the influence of displacement rate and rock type on q value are explored by mineral structure and fracture modes.A self-organized critical prediction method with q value is proposed.The results show that the probability density function(PDF)of EPs follows the q-Gaussian distribution.The displacement rate is positively correlated with q value.With the displacement rate increasing,the fracture mode changes,the damage degree intensifies,and the microcrack network becomes denser.The influence of rock type on q value is related to the burst intensity of energy release and the crack fracture mode.The q value of EPs can be used as an effective prediction index for rock failure like b value of acoustic emission(AE).The results provide useful reference and method for the monitoring and early warning of geological disasters.
基金supported by National Key R&D Program of China(No.2022YFC3004705)the National Natural Science Foundation of China(Nos.52074280,52227901 and 52204249)National Natural Science Foundation of China Youth Fund(No.52104230).
文摘Effective monitoring of the structural health of combined coal-rock under complex geological conditions by pressure stimulated currents(PSCs)has great potential for the understanding of dynamic disasters in underground engineering.To reveal the effect of this way,the uniaxial compression experiments with PSC monitoring were conducted on three types of coal-rock combination samples with different strength combinations.The mechanism explanation of PSCs are investigated by resistivity test,atomic force microscopy(AFM)and computed tomography(CT)methods,and a PSC flow model based on progressive failure process is proposed.The influence of strength combinations on PSCs in the progressive failure process are emphasized.The results show the PSC responses between rock part,coal part and the two components are different,which are affected by multi-scale fracture characteristics and electrical properties.As the rock strength decreases,the progressive failure process changes obviously with the influence range of interface constraint effect decreasing,resulting in the different responses of PSC strength and direction in different parts to fracture behaviors.The PSC flow model is initially validated by the relationship between the accumulated charges of different parts.The results are expected to provide a new reference and method for mining design and roadway quality assessment.
文摘A complete spinal cord injury model was established in experimental rabbits using the spinal cord clip compression method. Urodynamic examination was performed 2 weeks later to determine neurogenic bladder status. The rabbits were treated with anodal block stimulation at sacral anterior roots for 4 weeks. Electrical stimulation of sacral anterior roots improved urodynamic parameters of neurogenic bladder in rabbit models of complete spinal cord injury, effectively promoted urinary function, and relieved urinary retention. Immunohistochemistry results showed that a balance was achieved among expression of muscarinic receptor subunits M2, M3, ATP-gated ion channel P2X3 receptors, and 132-adrenergic receptor, and nerve growth factor expression decreased. These results suggested that long-term sacral anterior root stimulation of anodal block could'be used to treat neurogenic bladder in a rabbit model of complete spinal cord injury.
基金a grant for International Cooperation Project by Jilin Provincial Science and Technology Commission,No.20100735
文摘The sacral nerve anterior root consists of parasympathetic nerves(dominating urinary bladder detrusor)and somatic motor nerves(dominating urethral sphincter),and electrical stimulation to the sacral nerve anterior root induces simultaneous contraction of the bladder detrusor and urethral sphincter.Accordingly,urethral pressure exceeds intravesical pressure,resulting in little or no urination,kidney damage,and trembling of lower limbs due to high intravesical pressure.In the present study,sacral nerve posterior roots were transected in a spastic bladder rabbit model,followed by three-pole electrode and long-pulse electrical stimulation to the sacral anterior root.Intravesical and urethral pressures were simultaneously measured to verify the feasibility of anode inhibition to the sacral anterior root following induced detrusor contraction.As stimulus intensity increased,somatic motor nerves were increasingly inhibited; with a stimulus pulse width of 300 μs and stimulus current of 1.05 mA,urethral pressure was zero and average intravesical pressure was 3.84 kPa.In addition,detrusor contraction was displayed,and lower extremity trembling was significantly reduced.Three-pole electrode and long-pulse electrical stimulation to the sacral nerve anterior root induced detrusor contraction and inhibited low extremity trembling under electrical stimulation.
基金Supported by National Natural Science Foundation of China(31271674)Key Research Project of Colleges and Universities in Henan Province(17A180024)
文摘Allelopathic autotoxicity occurs when a plant releases toxic chemical substances into the environment which inhibits development and growth of the same plant species.Rehmannia glutinosa L.( R.glutinosa ) is one of the most common traditional Chinese medicines,whose productivity and quality,however,are seriously impacted by consecutive monoculture obstacle.Allelopathic autotoxicity is one reason for consecutive monoculture obstacle.In this paper,we reviewed the categories of allelochemicals,the methods of allelochemicals identification,and the mechanisms of allelopathic autotoxicity,which provides clues for further study of the molecular mechanisms of allelopathic autotoxicity and consecutive monoculture obstacle.
基金Supported by National Natural Science Foundation of China(31271674)Key Research Project of Colleges and Universities in Henan Province(17A180024)
文摘Rehmannia glutinosa L.is one of the important medicinal crops in China.Continuous cropping obstacle severely restricts the yield and quality of R.glutinosa,but its molecular mechanism is still unclear.In this study,with widely-planted "Wen 85-5" as an experiment material,based on the digital gene expression profiling (DGE) data of previous five stress treatments (continuous cropping,phenolic acid,salt,drought and waterlogging) and the first cropping and continuous cropping treatments of R.glutinosa in five different periods (seedling period,elongation period,early expanding period,middle expanding period and later expanding period),80 candidate genes (|log 2 ratio|≥1,FDR <0.001) specifically responding to continuous cropping obstacle in R.glutinosa were screened.Functional analysis revealed that the differentially expressed genes were involved in the secretion and endocytosis of root cells,which may suggest that the recognition and absorption of allelopathic autotoxins by the roots of R.glutinosa is an important factor that restricts the development of roots in continuous cropping of R.glutinosa.In order to accurately lock genes specifically responding to continuous cropping obstacle in R.glutinosa,continuous cropping soil extract and ferulic acid and p-hydroxybenzonic acid were used to treat aseptic plantlets of R.glutinosa,respectively,and it was confirmed through qRT-PCR that the expression levels of some genes under phenolic acid treatment changed more severely than that under the continuous cropping soil extract treatment,and four key genes involved in the response of R.glutinosa to continuous cropping were finally locked.This study lays a foundation for further exploration of the molecular mechanism of continuous cropping obstacle.
基金Supported by College Students’Innovation and Entrepreneurship Training Program of Tianjin Agricultural University (202110061151)
文摘After investigating the current situation of college students'employment and entrepreneurship environment and the existing problems and related policies in the Beijing-Tianjin-Hebei region under the background of the integration of Beijing-Tianjin-Hebei region,this project put forward some insights into the reform of university teaching.First,a questionnaire survey was conducted to understand the basic information of the respondents,the obstacles to starting a business,and the current situation of the entrepreneurial environment such as government assistance.The questionnaires were distributed in the questionnaire star.The data were summarized with Excel;reliability and validity analysis was performed with SPSS,and descriptive statistical analysis was performed with Excel;and then,one-way ANOVA and exploratory factor analysis were performed with SPSS,and confirmatory factor analysis was performed with the SEM structural equation.It was found that gender,educational background and major have a significant impact on choosing to start a business.The evaluation indexes of entrepreneurial environment were divided into two common factors:government policy assistance and government fund assistance,and eight specific influencing factors were obtained,and the model fit well.This paper analyzed the work that schools have to do in the process of college students'entrepreneurship and its impact on entrepreneurship,providing ideas for the government and schools to help college students start their own businesses in the future.
基金supported by Natural Science Foundation of Hebei Province (No. E2016202358)
文摘The nominal Li_(3-x)Fe_(2-x)Ti_x(PO_4)_(2.55)(VO_4)_(0.45)(x=0~0.3) compounds were synthesized by a sol-gel process.Different from the single V043 doping, further introduction of Ti^(4+) ion was easy to result in precipitation of a little secondary phases, besides the main NASICON products. The simultaneous substitution of Ti^(4+)and VO_4~3 for Fe^(3+) and PO_4~3,respectively, in the Li_3 Fe_2(PO_4)_3 resulted in a net improvement in the rate capability and cycling performance, as compared with the single Ti^(4+) or VO_4~3-substituted compound.The sample with x=0.2 presented a high initial discharging capacity of 125.4 mAh/g at the rate of 0.5 C,about 25% higher than the Ti^(4+)-substituted Li_(2.8)Fe_(1.8)Ti_(0.2)(PO_4)_3, and 102.6 mAh/g after 60 cycles at 2 C,about 12% higher than the single VO_4~3-substituted one. The high rate performance between 0.5 C to 10 C suggested that this sample had a good stability and reversibility. These results proved that the combination of the Ti^(4+) substitution for Fe^(3+) with the V043 substitution for PO_4~3 was a promising method of improving electrochemical performance of the studied Li_3 Fe_2(PO_4)_3 cathode material.