Analysis of the Internal Pressure in Tube Hydroforming and Its Experimental Investigation

这个过程的内部压力理论上并且试验性地被学习。外部负担特性和形成的试管水疗院的内部压力特性首先被讨论。根据字符的意见，然后，内部压力的函数和分类一般来说被介绍。压力分析，它收益标准上的效果和计算公式上的底也被研究并且发源。验证理论分析和导出的公式的修正，有不同内部压力的实验被执行，结果被比较并且讨论。它证明内部压力在这篇论文讨论并且发源的形成的试管水疗院和理论和公式起一个重要作用在实践是可行的。

Stress and Deformation Analysis of Cylinder-Crown Integrated Hydraulic Press with Large Capacity

Cylinder-crown integrated hydraulic press( CCIHP) is a new press structure. The hemispherical hydraulic cylinder also functions as a main portion of crown,which has lower weight and higher section modulus compared with the conventional hydraulic cylinder and press crown. In order to design cylinder-crown integrated hydraulic press with large capacity, the theoretical design of hemispherical hydraulic cylinder was first proposed,and the structural parameters of 150 MN CCIHP were listed. Then the simulation was carried out to analyze the stress and deformation of CCIHP,and weight comparison was conducted between CCIHP and conventional press. It is shown that the weight reduction for hydraulic cylinder and press crown is about 20% compared with that for conventional press,and the stress and deformation are both within the range of constraints including strength and stiffness conditions. It is possible to manufacture cylinder-crown integrated hydraulic press with large capacity.

Effect of Loading Paths on Hydroforming Tubular Square Components

The influence of loading path on tube hydroforming process is discussed in this paper with finiteelement simulation. Four different loading paths are utilized in simulating the forming process of square tubular component with hydroforming and the result of different loading path is presented. Among the result. the thickness distribution of bilinear loading path is the most uniform one. It shows that the increase of punch displacement in the stage of high pressure is beneficial to the forming of component for optimized Stress condition.

Type I IFN augments IL-27-dependent TRIM25 expression to inhibit HBV replication

Hepatitis B virus(HBV)can cause chronic hepatitis B,which may lead to cirrhosis and liver cancer.Type I interferon(IFN)is an approved drug for the treatment of chronic hepatitis B.However,the fundamental mechanisms of antiviral action by type I IFN and the downstream signaling pathway are unclear.TRIM25 is an IFN-stimulated gene(ISG)that has an important role in RIG-I ubiquitination and activation.Whether TRIM25 is induced in liver cells by type I IFN to mediate anti-HBV function remains unclear.Here we report that interleukin-27(IL-27)has a critical role in IFN-induced TRIM25 upregulation.TRIM25 induction requires both STAT1 and STAT3.In TRIM25 knockout HepG2 cells,type I IFN production was consistently attenuated and HBV replication was increased,whereas overexpression of TRIM25 in HepG2 cells resulted in elevated IFN production and reduced HBV replication.More interestingly,we found that TRIM25 expression was downregulated in HBV patients and the addition of serum samples from HBV patients could inhibit TRIM25 expression in HepG2 cells,suggesting that HBV might have involved a mechanism to inhibit antiviral ISG expression and induce IFN resistance.Collectively,our results demonstrate that type I IFN-induced TRIM25 is an important factor in inhibiting HBV replication,and the IFN-IL-27-TRIM25 axis may represent a new target for treating HBV infection.

Trade Barriers and Participation in the Global Value Chain:An Empirical Study Based on Anti-dumping toward China

This paper investigates the effects of trade barriers on China s participation in the global value chain(GVC)using a thorough decomposition approach for trade volume,total exports,final exports and intermediate exports.Our econometric results indicate that anti-dumping(AD)measures initiated by trade partners have restrained the process of China s participation in the GVC.From 2000 to 2014,AD measures reduced the foreign value-added rate of total,final and intermediate exports by 4.5 to 28.7 percent,3.4 to 17 percent and 1.2 to 8.5 percent,respectively.In addition,suffering the effects of AD measures,China s GVC position index declined by 8.2 percent to 28.6 percent during this period.Moreover,AD measures have increased industries'upstream index by 3.2 to 13.7 percent over the same period.These results imply that both the petition and approval of AD cases has had a negative influence on the extent and position of China s GVC participation.

Why Chinese Exports Face So Many Trade Remedy Actions： An Empirical Study Based on Multi-country and Multi-industry Data

This paper offers a comprehensive analysis of the reasons for the large number of trade remedy actions taken against China. Using a multi-country and multi-industry dataset, the present paper shows that the macroeconomic situation of China＇s partners has a great influence on the probability of trade frictions arising with China. Moreover, the more powerful the industry is, the more likely it is to take trade remedy actions against China. The empirical results reveal that China has been hurt under the operating mechanism of the WTO, and the number of free trade agreements is negatively related to the initiation and approval of trade remedy actions. Basically, the determinants for countervailing and double remedy measures are identical, while they are different from determinants of antidumping measures. Accordingly, strengthening communication with trade partners will alleviate friction between China and its trade partners. Meanwhile, making use of foreign lobbies power, actively integrating into the international trading system and participating in regional trade agreements are effective ways for China to deal with the ＂new normal＂ of trade frictions.

VGQ-Vor： extending virtual grid quadtree with Voronoi diagram for mobile k nearest neighbor queries over mobile objects

Performing mobile k nearest neighbor （MkNN） queries whilst also being mobile is a challenging problem. All the mobile objects issuing queries and/or being queried are mobile. The performance of this kind of query relies heav- ily on the maintenance of the current locations of the objects. The index used for mobile objects must support efficient up- date operations and efficient query handling. This study aims to improve the performance of the MkNN queries while re- ducing update costs. Our approach is based on an observa- tion that the frequency of one region changing between being occupied or not by mobile objects is much lower than the frequency of the position changes reported by the mobile ob- jects. We first propose an virtual grid quadtree with Voronoi diagram （VGQ-Vor）, which is a two-layer index structure that indexes regions occupied by mobile objects in a quadtree and builds a Voronoi diagram of the regions. Then we propose a moving k nearest neighbor （kNN） query algorithm on the VGQ-Vor and prove the correctness of the algorithm. The ex- perimental results show that the VGQ-Vor outperforms the existing techniques （Bx-tree, Bdual-tree） by one to three or- ders of magnitude in most cases.

Surgical treatment strategies for hemimasticatory spasms

To the Editor:Hemimasticatory spasm(HMS)is a relatively rare type of unilateral trigeminal nerve(TN)motor branch dysfunction,whose pathogenesis is currently unknown.The clinical manifestations of HMS are involuntary paroxysmal convulsions of the muscles innervated by the associated unilateral trigeminal motor branch.Recently,the academic community has proposed two etiologies for HMS:TN compression and central lesion theory.[1]Clinically,HMS must be distinguished from oromandibular dystonia,facial muscle spasm,multiple sclerosis pain spasm,and focal epilepsy.Generally,electromyography(EMG)can confirm the diagnosis.The current outcomes of multidrug and botulinum toxin injection treatments remain unsatisfactory.Only patients with cranial neurovascular conflicts have an excellent response to microvascular decompression(MVD)surgery.

Risks and Firms' Decision Making on Outward Foreign Direct Investment: An Empirical Analysis of China's State-owned Enterprises

This study explored how the risks encountered by Chinese state-owned enterprises(SOEs)affected their decision-making on outward foreign direct investment(OFDI),using data regarding the relationship between the host countries and China.The following conclusions were drawn.Larger SOEs with fixed capital exhibited a higher probability of conducting OFDI and did so on a larger scale.Various risks in host countries significantly hindered the OFDI of Chinese SOEs.In pursuit of natural resources,Chinese SOEs chose to take risks.The amount of OFDI by SOEs was positively related to the political,economic,and geographical relations between China and the corresponding hostcountry.