Due to the extensive use of various intelligent terminals and the popularity of network social tools,a large amount of data in the field of medical emerged.How to manage these massive data safely and reliably has beco...Due to the extensive use of various intelligent terminals and the popularity of network social tools,a large amount of data in the field of medical emerged.How to manage these massive data safely and reliably has become an important challenge for the medical network community.This paper proposes a data management framework of medical network community based on Consortium Blockchain(CB)and Federated learning(FL),which realizes the data security sharing between medical institutions and research institutions.Under this framework,the data security sharing mechanism of medical network community based on smart contract and the data privacy protection mechanism based on FL and alliance chain are designed to ensure the security of data and the privacy of important data in medical network community,respectively.An intelligent contract system based on Keyed-Homomorphic Public Key(KH-PKE)Encryption scheme is designed,so that medical data can be saved in the CB in the form of ciphertext,and the automatic sharing of data is realized.Zero knowledge mechanism is used to ensure the correctness of shared data.Moreover,the zero-knowledge mechanism introduces the dynamic group signature mechanism of chosen ciphertext attack(CCA)anonymity,which makes the scheme more efficient in computing and communication cost.In the end of this paper,the performance of the scheme is analyzed fromboth asymptotic and practical aspects.Through experimental comparative analysis,the scheme proposed in this paper is more effective and feasible.展开更多
Focal ischemic stroke（FIS）results from the lack of blood flow in a particular region of the brain and accounts for about 80%of all human strokes.Although tremendous efforts have been made in translational research,t...Focal ischemic stroke（FIS）results from the lack of blood flow in a particular region of the brain and accounts for about 80%of all human strokes.Although tremendous efforts have been made in translational research,the treatment strategies are still limited.Tissue plasminogen activator is the only FDA-approved drug currently available for acute stroke treatment,展开更多
基金supported by the NSFC(No.62072249)Yongjun Ren received the grant and the URLs to sponsors’websites is https://www.nsfc.gov.cn/.
文摘Due to the extensive use of various intelligent terminals and the popularity of network social tools,a large amount of data in the field of medical emerged.How to manage these massive data safely and reliably has become an important challenge for the medical network community.This paper proposes a data management framework of medical network community based on Consortium Blockchain(CB)and Federated learning(FL),which realizes the data security sharing between medical institutions and research institutions.Under this framework,the data security sharing mechanism of medical network community based on smart contract and the data privacy protection mechanism based on FL and alliance chain are designed to ensure the security of data and the privacy of important data in medical network community,respectively.An intelligent contract system based on Keyed-Homomorphic Public Key(KH-PKE)Encryption scheme is designed,so that medical data can be saved in the CB in the form of ciphertext,and the automatic sharing of data is realized.Zero knowledge mechanism is used to ensure the correctness of shared data.Moreover,the zero-knowledge mechanism introduces the dynamic group signature mechanism of chosen ciphertext attack(CCA)anonymity,which makes the scheme more efficient in computing and communication cost.In the end of this paper,the performance of the scheme is analyzed fromboth asymptotic and practical aspects.Through experimental comparative analysis,the scheme proposed in this paper is more effective and feasible.
基金supported by NIH NS069726 and NS094539America Heart Association 13GRANT17020004(to SD)
文摘Focal ischemic stroke（FIS）results from the lack of blood flow in a particular region of the brain and accounts for about 80%of all human strokes.Although tremendous efforts have been made in translational research,the treatment strategies are still limited.Tissue plasminogen activator is the only FDA-approved drug currently available for acute stroke treatment,
