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Hemoperfusion and continuous veno-venous hemodiafiltration for eliminating chlorfenapyr in poisoning patients
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作者 Yanqing Liu xiaoxia lu +6 位作者 Haochun Wang Ming Niu Renzheng Zhang Zhongying Liu Limei Han Xiaobo Peng Xigang Zhang 《World Journal of Emergency Medicine》 SCIE CAS CSCD 2024年第3期235-237,共3页
Chlorfenapyr is a liposoluble insecticide belonging to the pyrrole family.Chlorfenapyr is activated when the N-ethoxymethyl side chain breaks,forming a toxic metabolite,which uncouples oxidative phosphorylation in the... Chlorfenapyr is a liposoluble insecticide belonging to the pyrrole family.Chlorfenapyr is activated when the N-ethoxymethyl side chain breaks,forming a toxic metabolite,which uncouples oxidative phosphorylation in the mitochondria,inhibits the production of adenosine triphosphate (ATP),and leads to the death of cells and targe organisms.[1] Symptoms of chlorfenapyr poisoning in patients are mild and atypical in the early stage,especially in patients receiving low dose exposure;however,such cases are rare and may be ignored by physicians,often leading to delayed treatment.[2,3]. 展开更多
关键词 PATIENTS PERFUSION eliminating
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碳包覆Ti2Nb2O9纳米片的制备及其储钠性能 被引量:6
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作者 卢晓霞 董升阳 +2 位作者 陈志杰 吴朗源 张校刚 《物理化学学报》 SCIE CAS CSCD 北大核心 2020年第5期126-133,共8页
具有两种不同阳离子的二元金属氧化物在钠离子电池中可发生可逆的多电子反应,是一类非常具有应用前景的高容量负极材料。在本项工作中,通过离子交换法和化学剥离法得到HTiNbO5纳米片,采用水热法将其与蔗糖复合再经由后续热处理得到碳包... 具有两种不同阳离子的二元金属氧化物在钠离子电池中可发生可逆的多电子反应,是一类非常具有应用前景的高容量负极材料。在本项工作中,通过离子交换法和化学剥离法得到HTiNbO5纳米片,采用水热法将其与蔗糖复合再经由后续热处理得到碳包覆的Ti2Nb2O9纳米片材料。碳包覆的Ti2Nb2O9纳米片可用作钠离子电池的负极材料,具有更高的电子导电性和多的反应活性点以及快速的离子传输通道,在50 mA∙g^−1的电流密度下具有265.2 mAh∙g^−1的可逆容量。在0.5 A∙g^−1的大电流密度下,循环200圈之后比容量为160.9 mAh∙g^−1(容量保持率75.3%)。研究结果表明Ti2Nb2O9/C纳米片在钠离子电池中具有出色的充放电性能和循环稳定性,为钠离子电池负极材料提供了可行的新选择。 展开更多
关键词 钠离子电池 剥离 Ti2Nb2O9纳米片 碳包覆 负极材料
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Respiratory Viruses and Mycoplasma Pneumoniae Surveillance Among Hospitalized Children with Acute Respiratory Infections—Wuhan City,Hubei Province,China,September-November 2023
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作者 Ying Li Yi Yan +6 位作者 Jiaming Huang Yue Shi Hui Du Chao Xiong Kai Chen Di Liu xiaoxia lu 《China CDC weekly》 SCIE CSCD 2024年第8期139-142,共4页
Summary What is already known about this topic?Acute respiratory infections(ARIs)are a significant contributor to illness and death in children.There has been a notable rise in the occurrence of ARIs and the associate... Summary What is already known about this topic?Acute respiratory infections(ARIs)are a significant contributor to illness and death in children.There has been a notable rise in the occurrence of ARIs and the associated pathogens in China,which has garnered worldwide attention.What is added by this report?This study conducted a retrospective analysis of the clinical characteristics of children with ARIs in Wuhan City from September to November 2023. 展开更多
关键词 November WUHAN HUBEI
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Expression of Syk in non-small cell lung cancer and its relationship with clinicopathological parameters
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作者 Fen LAN Shengdao XIONG +2 位作者 Weining XIONG Guopeng XU xiaoxia lu 《Frontiers of Medicine》 SCIE CSCD 2009年第1期41-44,共4页
This study aims to research the expression of spleen tyrosine kinase(Syk)in non-small cell lung cancer(NSCLC)and the relationship between Syk and clinico-pathologic factors and p53.Immunohistochemistry was applied to ... This study aims to research the expression of spleen tyrosine kinase(Syk)in non-small cell lung cancer(NSCLC)and the relationship between Syk and clinico-pathologic factors and p53.Immunohistochemistry was applied to detect the expression of Syk and p53 protein in 39 cases of NSCLC(23 cases of lung squamous cell can-cer,16 cases of lung adenocarcinoma)and tumor-sur-rounding normal lung tissues.The positive rate of Syk was 46.15%(18/39)and 100%(39/39)in NSCLC and tumor-surrounding normal lung tissues,respectively.The expres-sion level of Syk in NSCLC was significantly lower than that in tumor-surrounding normal lung tissues(P=0.000).The Syk expression was positively correlated with the p53 expression in NSCLC specimens(P=0.025).There was no significant association between Syk expression and lymph node metastasis,differentiation degree,tumor size and tumor node metastasis(TNM).The present study demonstrated that Syk was aberrantly expressed in the NSCLC and might have a significant impact on tumor growth and progression. 展开更多
关键词 Syk kinase carcinoma non-small-cell lung tumor suppressor protein p53
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Prevalence,variation,and transmission patterns of human respiratory syncytial virus from pediatric patients in Hubei,China during 2020–2021
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作者 Yi Yan Decheng Wang +5 位作者 Ying Li Zhiyong Wu Haizhou Liu Yue Shi xiaoxia lu Di Liu 《Virologica Sinica》 SCIE CAS CSCD 2023年第3期363-372,共10页
Human respiratory syncytial virus(RSV)is a severe threat to children and a main cause of acute lower respiratory tract infections.Nevertheless,the intra-host evolution and inter-regional diffusion of RSV are little kn... Human respiratory syncytial virus(RSV)is a severe threat to children and a main cause of acute lower respiratory tract infections.Nevertheless,the intra-host evolution and inter-regional diffusion of RSV are little known.In this study,we performed a systematic surveillance in hospitalized children in Hubei during 2020–2021,in which 106 RSV-positive samples were detected both clinically and by metagenomic next generation sequencing(mNGS).RSV-A and RSV-B groups co-circulated during surveillance with RSV-B being predominant.About 46 high-quality genomes were used for further analyses.A total of 163 intra-host nucleotide variation(iSNV)sites distributed in 34 samples were detected,and glycoprotein(G)gene was the most enriched gene for iSNVs,with non-synonymous substitutions more than synonymous substitutions.Evolutionary dynamic analysis showed that the evolutionary rates of G and NS2 genes were higher,and the population size of RSV groups changed over time.We also found evidences of inter-regional diffusion from Europe and Oceania to Hubei for RSV-A and RSV-B,respectively.This study highlighted the intra-host and inter-host evolution of RSV,and provided some evi-dences for understanding the evolution of RSV. 展开更多
关键词 Respiratory syncytial virus(RSV) Intra-host single nucleotide variation(iSNV) Evolutionary dynamic Inter-regional diffusion
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文化差异对企业社会责任的影响——基于美国Verizon公司和越南VNPT集团的案例比较研究
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作者 白景坤 阮氏清恒 卢晓侠 《跨文化管理》 2016年第1期137-153,共17页
企业社会责任运动促成了相关国际标准体系的形成,但实践中源于西方发达国家的标准体系却成为后发展国家参与国际竞争的无形壁垒。现有文献多将各国企业社会责任的差异归结为经济因素,很少考虑甚至忽略文化因素的影响。本文选取美国Veri... 企业社会责任运动促成了相关国际标准体系的形成,但实践中源于西方发达国家的标准体系却成为后发展国家参与国际竞争的无形壁垒。现有文献多将各国企业社会责任的差异归结为经济因素,很少考虑甚至忽略文化因素的影响。本文选取美国Verizon公司和越南VNPT集团作为典型案例进行比较分析,探讨文化差异对企业社会责任的内容及实施方式的影响。研究发现,文化差异使得人们对企业社会责任产生不同的认知,进而对企业社会责任的实施方式产生不同影响。由此,企业社会责任国际标准体系构建过程中,为减少执行过程中的负效应,需考虑到国家和地区文化差异的影响。 展开更多
关键词 文化差异 社会责任 案例比较 VNPT VERIZON
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Diagnosis, treatment, and prevention of 2019 novel coronavirus infection in children: experts' consensus statement 被引量:62
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作者 Kunling Shen Yonghong Yang +17 位作者 Tianyou Wang Dongchi Zhao Yi Jiang Runming Jin Yuejie Zheng Baoping Xu Zhengde Xie Likai Lin Yunxiao Shang xiaoxia lu Sainan Shu Yan Bai Jikui Deng Min lu Leping Ye Xuefeng Wang Yongyan Wang Liwei Gao 《World Journal of Pediatrics》 SCIE CAS CSCD 2020年第3期223-231,共9页
Since the outbreak of 2019 novel coronavirus infection (2019-nCoV) in Wuhan City,China,by January 30,2020,a total of 9692 confirmed cases and 15,238 suspected cases have been reported around 31 provinces or cities in ... Since the outbreak of 2019 novel coronavirus infection (2019-nCoV) in Wuhan City,China,by January 30,2020,a total of 9692 confirmed cases and 15,238 suspected cases have been reported around 31 provinces or cities in China.Among the confirmed cases,1527 were severe cases,171 had recovered and been discharged at home,and 213 died.And among these cases,a total of 28 children aged from 1 month to 17 years have been reported in China.For standardizing prevention and management of 2019-nCoV infections in children,we called up an experts' committee to formulate this experts' consensus statement.This statement is based on the Novel Coronavirus Infection Pneumonia Diagnosis and Treatment Standards (the fourth edition) (National Health Committee) and other previous diagnosis and treatment strategies for pediatric virus infections.The present consensus statement summarizes current strategies on diagnosis,treatment,and prevention of 2019-nCoV infection in children. 展开更多
关键词 PREVENTION DIAGNOSIS TREATMENT
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Impact of water depth on the distribution of iGDGTs in the surface sediments from the northern South China Sea: applicability of TEXss in marginal seas
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作者 Jiali CHEN Pengju HU +6 位作者 Xing LI Yang YANG Jinming SONG Xuegang LI Huamao YUAN sing Li xiaoxia lu 《Frontiers of Earth Science》 SCIE CAS CSCD 2018年第1期95-107,共13页
The TEXh86 paleothermometer on the base of isoprenoid glycerol dialkyl glycerol tetraethers (iGDGTs) has been widely applied to various marine settings to reconstruct past sea surface temperatures (SSTs). However,... The TEXh86 paleothermometer on the base of isoprenoid glycerol dialkyl glycerol tetraethers (iGDGTs) has been widely applied to various marine settings to reconstruct past sea surface temperatures (SSTs). However, it remains uncertain how well this proxy reconstructs SSTs in marginal seas. In this study, we analyze the environmental factors governing distribution ofiGDGTs in surface sediments to assess the applicability of TEXH86 paleothermometer in the South China Sea (SCS). Individual iGDGT concentrations increase gradually eastwards. Redundancy analysis based on the relative abundance of an individual iGDGT compound and environmental parameters suggests that water depth is the most influential factor to the distribution of iGDGTs, because thaumarchaeota communities are water-depth dependent. Interestingly, the SST difference (AT) between TEXH86 derived temperature and remote-sensing SST is less than 1°C in sediments with water depth 〉 200 m, indicating that TEXH86 was the robust proxy to trace the paleo-SST in the region if water depth is greater than 200 m. 展开更多
关键词 iGDGTs DISTRIBUTION South China Sea(SCS) sea surface temperature water depth
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Tim-3 mRNA expression in peripheral blood lymphocytes from asthmatic patients
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作者 xiaoxia lu Weikun HU +2 位作者 Shengdao XIONG Guopeng XU Fen LAN 《Frontiers of Medicine》 SCIE CSCD 2009年第2期187-190,共4页
The study aimed to detect the expression of the Th1-specific cell surface protein T cell Ig and mucin domain-containing molecule-3(Tim-3)mRNA peripheral blood lymphocytes isolated from asthmaticin patients and to exami... The study aimed to detect the expression of the Th1-specific cell surface protein T cell Ig and mucin domain-containing molecule-3(Tim-3)mRNA peripheral blood lymphocytes isolated from asthmaticin patients and to examine the correlation among Tim-3 mRNA,interleukin-4(IL-4),interferon-γ(IFN-γ)level,and FEV1/FVC(force expiratory volume in one second/forced vital capacity)to explore the role of Tim-3 in the development and progression of asthmatic inflammation.Tim-3 mRNA expression was detected by reverse transcription polymerase chain reaction(RT-PCR).The IL-4 and IFN-γlevels were determined by using enzyme-linked immunosorbent assay(ELISA).The correlation among Tim-3 mRNA,IL-4,IFN-γlevel,and pulmonary ventilatory capacity was analyzed.The expres-sion of Tim-3 mRNA in patients with acute asthma exacerbation was 0.39�0.06,significantly higher than that in patients at the remission stage and controls(0.18�0.05 and 0.07�0.03,P<0.05).The level of IL-4 in patients with acute asthma exacerbation was 68.42�10.54,significantly higher than that in the patients at the remission stage and controls(41.83�9.37 and 32.75�8.16,P<0.05).The level of IL-4 in patients in remission was significantly higher than that in controls(P<0.05).The level of IFN-γin patients with acute asthma exacerbation was 65.74�7.85,significantly lower than that in patients in remission and the control group(120.84�11.62 and 139.65�13.47,P<0.05).The level of IFN-γin patients in asthma remission was significantly lower than that in controls(P<0.05).Tim-3 mRNA expression was positively correlated with the level of IL-4(r=0.68,P<0.05)and negatively with the level of IFN-γand pulmonary ventilatory capacity(r=–0.85,r=–0.76,both P<0.01).The increased expression of Tim-3 mRNA in peripheral blood lymphocytes might be involved in the development and progression of asthmatic inflammation. 展开更多
关键词 ASTHMA airway inflammation peripheral blood lymphocyte TIM-3
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