[Objectives]To explore the stability of Naomai Xingshen Capsules.[Methods]Accelerated test and long-term test were carried out to investigate the changes in properties,identification,moisture,disintegration time and m...[Objectives]To explore the stability of Naomai Xingshen Capsules.[Methods]Accelerated test and long-term test were carried out to investigate the changes in properties,identification,moisture,disintegration time and microbial limit of Naomai Xingshen Capsules.[Results]There were basically no changes in all indicators for the three batches of samples(after 6-month accelerated test and 24-month long-term test),and they all met the requirements of quality standards.[Conclusions]The preparation of Naomai Xingshen Capsules is stable and reliable,and the stability test provides a reliable basis for its expiration date.展开更多
[Objectives]To investigate the stability of Shuji tablets.[Methods]Accelerated test and long-term test were used to investigate the changes of tablet properties,weight difference,alcohol-soluble extract,disintegration...[Objectives]To investigate the stability of Shuji tablets.[Methods]Accelerated test and long-term test were used to investigate the changes of tablet properties,weight difference,alcohol-soluble extract,disintegration time and microbial limit.[Results]All the indicators of the three batches of samples(after 6 months of accelerated test and 18 months of long-term test)basically remained unchanged and all met the standards of the quality standard.[Conclusions]The preparation is stable and reliable,and the stability test provides a reliable basis for its validity.展开更多
The purpose of this paper is to discuss the development of medical informatization in the era of big data.Through literature review and theoretical analysis,the development of medical informatization in the era of big...The purpose of this paper is to discuss the development of medical informatization in the era of big data.Through literature review and theoretical analysis,the development of medical informatization in the era of big data is deeply discussed.The results show that medical informatization has developed rapidly in the era of big data,and its role in clinical decision-making,scientific research,teaching,and management has become increasingly prominent.The development of medical informatization in the era of big data has important purposes and methods,which can produce important results and conclusions and provide strong support for the development of the medical field.展开更多
Dialdehyde sodium alginate(DSA)is an alternative chrome-free tanning material for fur production.To obtain satisfactory resultant fur and provide suggestions for the usage of DSA in fur making,the general properties o...Dialdehyde sodium alginate(DSA)is an alternative chrome-free tanning material for fur production.To obtain satisfactory resultant fur and provide suggestions for the usage of DSA in fur making,the general properties of DSA tanned sheep fur were systematically investigated.The tanning mechanism of DSA was analyzed and it was verified that DSA was mainly combined with collagen fiber by forming Schiff base covalent bonds while supplemented by a small number of hydrogen bonds and ionic bonds.Due to the acid sensitivity of Schiff base structure,DSA tanned fur had poor resistance to acid rinsing but had excellent resistance to washing and good fatliquoring performance.Also,it had good resistances to yellowing and reductant.After being retanned by chrome tanning agent,the fur was capable of enduring a high-temperature dyeing process(68°C for 8 h).Overall,DSA tanned sheep fur had favorable properties under appropriate post-tanning processing conditions to manufacture light-colored or dark-colored fur products with desirable physical properties.展开更多
Natural products derived from marine microorganisms have been received great attention as a potential source of new compound entities for drug discovery.The unique marine environment brings us a large group of halogen...Natural products derived from marine microorganisms have been received great attention as a potential source of new compound entities for drug discovery.The unique marine environment brings us a large group of halogen-containing natural products with abundant biological functionality and good drugability.Meanwhile,biosynthetically halogenated reactions are known as a significant strategy used to increase the pharmacological activities and pharmacokinetic properties of compounds.Given that a tremendous increase in the number of new halogenated compounds from marine microorganisms in the last five years,it is necessary to summarize these compounds with their diverse structures and promising bioactivities.In this review,we have summarized the chemistry,biosynthesis(related halogenases),and biological activity of a total of 316 naturally halogenated compounds from marine microorganisms covering the period of 2015 to May 2021.Those reviewed chlorinated and brominated compounds with the ratio of 9:1 were predominantly originated from 36 genera of fungi(62%)and 9 bacterial strains(38%)with cytotoxic,antibacterial,and enzyme inhibitory activities,structural types of which are polyketides(38%),alkaloids(27%),phenols(11%),and others.This review would provide a plenty variety of promising lead halogenated compounds for drug discovery and inspire the development of new pharmaceutical agents.展开更多
Aerogels are predominantly mesoporous,extremely lightweight,low density(∼0.003 g/cm 3)and thermally insulat-ing materials.Over the years,aerogels have gained increasing attention due to their extraordinary properties...Aerogels are predominantly mesoporous,extremely lightweight,low density(∼0.003 g/cm 3)and thermally insulat-ing materials.Over the years,aerogels have gained increasing attention due to their extraordinary properties(light,heat,sound,electricity and force)and application potentials in varieties of fields.Several studies have been carried out regarding aerogel preparation and its applications in coatings on different substrates.In this review,an overview of aerogels preparation and their application progress in coatings of most common substrates is presented.Attention is paid to aerogel coatings of textiles,leather,and substrates other than leather and textiles for special functionali-ties that could address the application progress in coatings.This review will help to inspire scientists and engineers towards novel aerogel materials and technologies to boost the industrial fabrication of flexible advanced materials.展开更多
The evolution of the spin density vectors(SDVs) is studied in a strongly focused composite field. It is found that the SDVs can be spiral along the propagation axis, and they are perpendicular to the ysdirection on th...The evolution of the spin density vectors(SDVs) is studied in a strongly focused composite field. It is found that the SDVs can be spiral along the propagation axis, and they are perpendicular to the ysdirection on the ysaxis. This behavior is governed by the Gouy phase difference between the field polarization components. The 60° rotation of the spatial distribution of the transverse SDVs is also generated, which is found to be controlled by the Gouy phase difference between the field orbital angular momentum modes. Additionally, the spin density singularities are observed in the evolution of the SDVs.展开更多
基金Supported by Medical Research Project of Zhongshan City Health and Family Planning Bureau,Guangdong Province(2015J050)。
文摘[Objectives]To explore the stability of Naomai Xingshen Capsules.[Methods]Accelerated test and long-term test were carried out to investigate the changes in properties,identification,moisture,disintegration time and microbial limit of Naomai Xingshen Capsules.[Results]There were basically no changes in all indicators for the three batches of samples(after 6-month accelerated test and 24-month long-term test),and they all met the requirements of quality standards.[Conclusions]The preparation of Naomai Xingshen Capsules is stable and reliable,and the stability test provides a reliable basis for its expiration date.
基金Science and Technology Program of Zhongshan City,Guangdong Province(2014A1FC138)。
文摘[Objectives]To investigate the stability of Shuji tablets.[Methods]Accelerated test and long-term test were used to investigate the changes of tablet properties,weight difference,alcohol-soluble extract,disintegration time and microbial limit.[Results]All the indicators of the three batches of samples(after 6 months of accelerated test and 18 months of long-term test)basically remained unchanged and all met the standards of the quality standard.[Conclusions]The preparation is stable and reliable,and the stability test provides a reliable basis for its validity.
文摘The purpose of this paper is to discuss the development of medical informatization in the era of big data.Through literature review and theoretical analysis,the development of medical informatization in the era of big data is deeply discussed.The results show that medical informatization has developed rapidly in the era of big data,and its role in clinical decision-making,scientific research,teaching,and management has become increasingly prominent.The development of medical informatization in the era of big data has important purposes and methods,which can produce important results and conclusions and provide strong support for the development of the medical field.
基金This work was financially supported by the National Key R&D Program(2017YFB0308500).
文摘Dialdehyde sodium alginate(DSA)is an alternative chrome-free tanning material for fur production.To obtain satisfactory resultant fur and provide suggestions for the usage of DSA in fur making,the general properties of DSA tanned sheep fur were systematically investigated.The tanning mechanism of DSA was analyzed and it was verified that DSA was mainly combined with collagen fiber by forming Schiff base covalent bonds while supplemented by a small number of hydrogen bonds and ionic bonds.Due to the acid sensitivity of Schiff base structure,DSA tanned fur had poor resistance to acid rinsing but had excellent resistance to washing and good fatliquoring performance.Also,it had good resistances to yellowing and reductant.After being retanned by chrome tanning agent,the fur was capable of enduring a high-temperature dyeing process(68°C for 8 h).Overall,DSA tanned sheep fur had favorable properties under appropriate post-tanning processing conditions to manufacture light-colored or dark-colored fur products with desirable physical properties.
基金financially supported by the Natural Science Foundation of Guangxi Province(Nos.2020GXNSFGA297002,2021GXNSFDA075010,2020GXNSFBA159001)the Special Fund for Bagui Scholars of Guangxi Province(Y.Liu),the National Natural Science Foundation of China(Nos.22007019,U20A20101)+1 种基金the Specific Research Project of Guangxi for Research Bases and Talents(AD20297003)the Open Project of CAS Key Laboratory of Tropical Marine Bio-resources and Ecology(LMB20211005).
文摘Natural products derived from marine microorganisms have been received great attention as a potential source of new compound entities for drug discovery.The unique marine environment brings us a large group of halogen-containing natural products with abundant biological functionality and good drugability.Meanwhile,biosynthetically halogenated reactions are known as a significant strategy used to increase the pharmacological activities and pharmacokinetic properties of compounds.Given that a tremendous increase in the number of new halogenated compounds from marine microorganisms in the last five years,it is necessary to summarize these compounds with their diverse structures and promising bioactivities.In this review,we have summarized the chemistry,biosynthesis(related halogenases),and biological activity of a total of 316 naturally halogenated compounds from marine microorganisms covering the period of 2015 to May 2021.Those reviewed chlorinated and brominated compounds with the ratio of 9:1 were predominantly originated from 36 genera of fungi(62%)and 9 bacterial strains(38%)with cytotoxic,antibacterial,and enzyme inhibitory activities,structural types of which are polyketides(38%),alkaloids(27%),phenols(11%),and others.This review would provide a plenty variety of promising lead halogenated compounds for drug discovery and inspire the development of new pharmaceutical agents.
基金This work was financially supported by the National Foreign Experts Program-Foreign Youth Talent Program(QN20200173001)the National Key R&D Pro-gram(2020YFE0203800)the Research and development project of China Leather and Footwear Research Institute Co.Ltd.(2021PGX02).
文摘Aerogels are predominantly mesoporous,extremely lightweight,low density(∼0.003 g/cm 3)and thermally insulat-ing materials.Over the years,aerogels have gained increasing attention due to their extraordinary properties(light,heat,sound,electricity and force)and application potentials in varieties of fields.Several studies have been carried out regarding aerogel preparation and its applications in coatings on different substrates.In this review,an overview of aerogels preparation and their application progress in coatings of most common substrates is presented.Attention is paid to aerogel coatings of textiles,leather,and substrates other than leather and textiles for special functionali-ties that could address the application progress in coatings.This review will help to inspire scientists and engineers towards novel aerogel materials and technologies to boost the industrial fabrication of flexible advanced materials.
基金supported by the National Natural Science Foundation of China(NSFC)(No.11974281)the Natural Science Basic Research Plan in Shaanxi Province of China(No.2020JM-116)。
文摘The evolution of the spin density vectors(SDVs) is studied in a strongly focused composite field. It is found that the SDVs can be spiral along the propagation axis, and they are perpendicular to the ysdirection on the ysaxis. This behavior is governed by the Gouy phase difference between the field polarization components. The 60° rotation of the spatial distribution of the transverse SDVs is also generated, which is found to be controlled by the Gouy phase difference between the field orbital angular momentum modes. Additionally, the spin density singularities are observed in the evolution of the SDVs.
