Epidemiology of biliary tract cancer in China:A narrative review

Biliary tract cancer(BTC)is a group of rare malignancies that affect the gallbladder and bile ducts.Although rare,BTC is becoming a significant public health burden in China,particularly among males and older individuals.The increasing trends in BTC incidence and mortality in China are influenced by various demographic,environmental,and lifestyle factors.In this review,we examine available epidemiological data on the incidence,mortality,prognosis,and trends of different BTC subtypes in China.We also discuss the challenges and opportunities for improving the prevention,diagnosis,and management of BTC in China,and identify areas for further research and intervention.The article aims to provide a better understanding of the epidemiological features of BTC in China and to inform public health strategies and clinical practice.

纳米碳标记对肥胖胃癌患者根治术淋巴结获取数目的影响

目的探讨纳米碳标记对肥胖胃癌患者根治术后淋巴结获取数目的影响。方法回顾性分析2015年1月至2019年12月期间在郑州大学附属肿瘤医院接受胃癌D2根治术127例肥胖患者的临床资料,依据患者术中是否注射纳米碳分为2组:64例患者术中未注射纳米碳者设为对照组,63例患者术中注射纳米碳者设为研究组,分析两组的术中情况及术后淋巴结获取情况。结果对照组手术时间(160±31)min,研究组手术时间(168±28)min,差异无统计学意义(t=-1.521 P=0.445);对照组术中出血量为(234±82)ml,研究组术中出血量(238±84)ml,差异无统计学意义(t=-0.295,P=0.846)。淋巴结检出情况:对照组在第一站淋巴结检出数目、第二站淋巴结检出数目、总淋巴结检出数目、直径<5 mm淋巴结数目方面均少于研究组[(10.4±3.8)枚比(24.5±10.6)枚,t=-10.054;(6.6±2.8)枚比(16.8±7.3)枚,t=-10.381;(17.1±6.4)枚比(41.2±17.6)枚,t=-10.293;(3.9±2.5)枚比(21.2±9.1)枚,t=-14.662],差异均有统计学意义(均P<0.05)。研究组在阳性淋巴结检出数目方面多于对照组[(5.9±6.2)枚比(4.2±3.4)枚,t=-1.963],但两组差异无统计学意义(P>0.05)。研究组共检出黑染淋巴结1542枚,淋巴结黑染率59.44%(1542/2594)。结论术中纳米碳的应用可显著提高肥胖(BMI≥25 kg/m^(2))胃癌患者根治术后淋巴结的获取数目,其临床意义有待进一步明确。