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Time-synchronous-averaging-spectrum based on super-resolution analysis and application in bearing fault signal identification
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作者 Zengle REN Yuan WANG +2 位作者 Huiyue TANG xin'an chen Wei FENG 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 SCIE EI CAS CSCD 2024年第7期573-585,共13页
Time-synchronous-averaging(TSA)is based on the idea of denoising by averaging,and it extracts the periodic components of a quasiperiodic signal and keeps the extracted waveform undistorted.This paper studies the mathe... Time-synchronous-averaging(TSA)is based on the idea of denoising by averaging,and it extracts the periodic components of a quasiperiodic signal and keeps the extracted waveform undistorted.This paper studies the mathematical properties of TSA,where three propositions are given to reveal the nature of TSA.This paper also proposes a TSA-spectrum based on super-resolution analysis and it decomposes a signal without using any base function.In contrast to discrete Fourier transform spectrum(DFT-spectrum),which is a spectrum in frequency domain,TSA-spectrum is a period-based spectrum,which can present more details of the cross effects between different periodic components of a quasiperiodic signal.Finally,a case study is carried out using bearing fault analysis to illustrate the performance of TSA-spectrum,where the rotation speed fluctuation of the shaft is estimated,which is about 0.12 ms difference.The extracted fault signals are presented and some insights are provided.We believe that this paper can provide new motivation for TSA-spectrum to be widely used in applications involving quasiperiodic signal processing(QSP). 展开更多
关键词 Time-synchronous-averaging(TSA) SPECTRUM Quasiperiodic signal processing(QSP) Super-resolution analysis Bearingfaultdetection
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11β-羟基类固醇脱氢酶Ⅰ型在不同年龄段大鼠眼内的表达与分布
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作者 陈薪安 林永 叶菊秀 《中华眼视光学与视觉科学杂志》 CAS CSCD 2022年第8期561-567,共7页
目的:观察糖皮质激素代谢酶11β-羟基类固醇脱氢酶Ⅰ型(11β-HSD1)在不同年龄Sprague-Dawlay(SD)大鼠眼内的表达与分布。方法:实验研究。将SD大鼠按年龄分为6组:1~2日龄新生组(PND1)、5~6日龄组(PND5)、10~11日龄组(PND10)、14~15日龄... 目的:观察糖皮质激素代谢酶11β-羟基类固醇脱氢酶Ⅰ型(11β-HSD1)在不同年龄Sprague-Dawlay(SD)大鼠眼内的表达与分布。方法:实验研究。将SD大鼠按年龄分为6组:1~2日龄新生组(PND1)、5~6日龄组(PND5)、10~11日龄组(PND10)、14~15日龄刚开眼组(PND15)、20~21日龄组(PND20)和8~9周龄成年组(M),每组6只。采用免疫组织化学染色法(IHC)检测从新生、开眼到成年等不同发育阶段SD大鼠眼组织内11β-HSD1蛋白的表达和分布情况,并通过Real time RT-PCR和Western blot进一步验证11β-HSD1在不同年龄段大鼠视网膜内的表达差异。组间数据比较采用单因素方差分析或t检验分析。结果:IHC显示11β-HSD1在各年龄组SD大鼠眼角膜、虹膜、视网膜、脉络膜、晶状体、睫状体等组织中均有表达,新生SD大鼠眼组织中的11β-HSD1阳性细胞数更多,染色更明显。Real time RT-PCR结果显示,角膜内11β-HSD1 mRNA相对表达量在SD大鼠出生后10 d达到高峰,SD大鼠开眼后开始逐渐下降,差异有统计学意义(F=8.40,P<0.001)。开眼前SD大鼠视网膜内的11β-HSD1 mRNA相对表达量高于开眼后和成年,差异有统计学意义(F=83.50,P<0.001)。Western bolt进一步证实,新生大鼠视网膜内的11β-HSD1蛋白表达量高于刚开眼大鼠和成年大鼠,差异有统计学意义(t=4.76,P=0.009;t=4.24,P=0.013)。结论:11β-HSD1在SD大鼠眼组织内广泛分布,其表达量随年龄而变化,开眼前SD大鼠眼组织尚未分化发育成熟,其表达量较高,提示11β-HSD1可能与SD大鼠眼组织的分化、发育和成熟有关。 展开更多
关键词 11β-羟基类固醇脱氢酶Ⅰ型 糖皮质激素 眼组织 表达 发育
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