The value of IgM and IgG contents for the diagnosis and judgment of mycoplasma pneumonia in children

Objective: To explore the value of IgM and IgG contents for the diagnosis and judgment of mycoplasma pneumonia in children. Methods: 560 children with mycoplasma pneumonia who received inpatient treatment in our hospital between October 2016 and October 2017 were selected as mycoplasma pneumonia group, and 200 healthy children who received vaccination in our hospital during the same period were selected as normal control group. The differences in peripheral blood IgM and IgG contents as well as serum inflammatory factor and pulmonary surfactant protein contents were compared between the two groups, and Pearson test was used to evaluate the inner link of peripheral blood IgM and IgG contents with inflammatory factors and pulmonary surfactant proteins in children with mycoplasma pneumonia. Results: Peripheral blood IgM and IgG contents of mycoplasma pneumonia group were higher than those of normal control group;serum inflammatory factors MCP-4, IL-5, IL-13, IL-17, IL-18 and IL-23 contents were higher than those of normal control group;serum pulmonary surfactant proteins SP-A, SP-B, SP-C and SP-D contents were higher than those of normal control group. Correlation analysis showed that peripheral blood IgM and IgG contents in children with mycoplasma pneumonia were positively correlated with the contents of inflammatory factors and pulmonary surfactant proteins. Conclusion: Peripheral blood IgM and IgG contents are abnormally high in children with mycoplasma pneumonia, and they are closely related to the inflammatory response and lung injury degree.

Effect of proximal contact strength on the three-dimensional displacements of implant-supported cantilever fixed partial dentures under axial loading

Objective:This study investigated the effect of proximal contact strength on the three-dimensional displacements of cantilever fixed partial denture(CFPD) under vertically concentrated loading with digital laser speckle(DLS) technique.Methods:Fresh mandible of beagle dog was used to establish the implant-supported CFPD for specimen.DLS technique was employed for measuring the three-dimensional displacement of the prosthesis under vertically concentrated loading ranging from 200 to 3 000 g.The effect of the contact tightness on the displacement of CFPD was investigated by means of changing the contact tightness.Results:When an axial concentrated loading was exerted on the pontic of the implant-supported CFPD,the displacement of the CFPD was the greatest.The displacement of the prosthesis decreased with the increase of contact strength.When the contact strength was 0,0.95,and 3.25 N,the displacement of the buccolingual direction was smaller than that of the mesiodistal direction but greater than that of the occlusogingival direction.When the force on the contact area was 6.50 N,the mesiodistal displacement of the prosthesis was the biggest while the buccolingual displacement was the smallest.Conclusions:The implant supported CFPD is an effective therapy for fully or partially edentulous patients.The restoration of the contact area and the selection of the appropriate contact strength can reduce the displacement of the CFPD,and get a better stress distribution.The most appropriate force value is 3.25 N in this study.