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肝脏血管周上皮样细胞瘤的诊治分析 被引量:4
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作者 刘河 刘浩 +6 位作者 石荣 蒋波 汪新天 陈晨 揭敏 张智桦 李浩 《中国现代医学杂志》 CAS 北大核心 2021年第7期22-27,共6页
目的探讨肝脏血管周上皮样细胞瘤(PEComa)的临床特点、诊断与治疗。方法回顾性分析2002年1月—2020年9月湖南师范大学附属第一医院收治的101例肝脏PEComa患者资料。其中,女性95例,男性6例;年龄27~63岁,中位年龄47岁。肿瘤平均直径4.7 c... 目的探讨肝脏血管周上皮样细胞瘤(PEComa)的临床特点、诊断与治疗。方法回顾性分析2002年1月—2020年9月湖南师范大学附属第一医院收治的101例肝脏PEComa患者资料。其中,女性95例,男性6例;年龄27~63岁,中位年龄47岁。肿瘤平均直径4.7 cm。采用χ2检验或Fisher精确概率法和Logistic回归模型分析肝脏PEComa术后复发的影响因素。结果99例患者行手术治疗,2例患者仅行超声引导下肝肿块穿刺活检。术后病理诊断均为肝脏PEComa。免疫组织化学检测人黑色素瘤标志物(Melan-A、Melanoma)和肌源性标志物SMA均阳性,99例患者血管源性标志物CD34为阳性。随访2~212个月,复发11例。肿瘤最大直径是否≥5 cm、有无初始症状及Ki-67阳性表达率是否>10%与肝脏PEComa复发有关。Logistic回归模型分析显示,肿瘤最大直径≥5 cm[OR=4.893(95%CI:1.045,22.903)]和有初始症状[OR=6.501(95%CI:1.384,30.551])为肝脏PEComa复发的独立危险因素(P<0.05)。结论肝脏PEComa好发于中年女性,影像学表现具有一定的特异性,但确诊率仍较低,确诊依靠病理学检查,外科手术为主要的治疗方式。由于PEComa的恶性潜能,尤其是存在复发的独立危险因素时,术后应密切随访。 展开更多
关键词 肝脏肿瘤 血管周上皮样细胞瘤 外科治疗 预后
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Influence of Microstructural Evolution on the Hot Deformation Behavior of an Fe–Mn–Al Duplex Lightweight Steel 被引量:6
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作者 Li-Xiong Xu Hui-Bin Wu xin-tian wang 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 2018年第4期389-400,共12页
The hot deformation behavior of Fe-26Mn-6.2A1-0.05C steel was studied by experimental hot compression tests in the temperature range of 800-1050℃ and strain rate range of 0.01-30 s-1 on a Gleeble-3500 thermal simulat... The hot deformation behavior of Fe-26Mn-6.2A1-0.05C steel was studied by experimental hot compression tests in the temperature range of 800-1050℃ and strain rate range of 0.01-30 s-1 on a Gleeble-3500 thermal simulation machine.The microstructural evolution during the corresponding thermal process was observed in situ by confocal laser scanning microscopy.Electron backscattered diffraction and transmission electron microscopy analyses were carried out to observe the microstructural morphology before and after the hot deformation.Furthermore,interrupted compression tests were conducted to correlate the microstructural characteristics and softening mechanisms at different deformation stages.The results showed that hot compression tests of this steel were all carried out on a duplex matrix composed of austenite and fi-ferrite.As the deformation temperature increased from 800 to 1050℃,the volume fraction of austenite decreased from 70.9% to 44.0%,while that of 6-ferrite increased from 29.1% to 56.0%.Due to the different stress exponents(n)and apparent activation energies(Q),the generated strain was mostly accommodated by δ-ferrite at the commencement of deformation,and then both dynamic recovery and dynamic recrystallization occurred earlier in δ-ferrite than in austenite.This interaction of strain partitioning and unsynchronized softening behavior caused an abnormal hot deformation behavior profile in the Fe-Mn-A1 duplex steel,such as yield-like behavior,peculiar work-hardening behavior,and dynamic softening behavior,which are influenced by not only temperature and strain rate but also by microstructural evolution. 展开更多
关键词 Microstructural evolution Dual-phase steel Lightweight component Hot deformation Dynamic recrystallization
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Tensile deformation behavior of nickel-free high-manganese austenitic cryogenic-temperature steel 被引量:1
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作者 xin-tian wang Hui-bin Wu +3 位作者 Yang Gu Li-xiong Xu Peng-cheng Zhang Qi-bo Tang 《Journal of Iron and Steel Research(International)》 SCIE EI CSCD 2022年第5期793-801,共9页
Nickel-free high-manganese austenitic Fe–24.4Mn–4.04Al–0.057C steel was produced by smelting,and the homogenized forged billet was hot-rolled.The plastic deformation mechanism was investigated through tensile testi... Nickel-free high-manganese austenitic Fe–24.4Mn–4.04Al–0.057C steel was produced by smelting,and the homogenized forged billet was hot-rolled.The plastic deformation mechanism was investigated through tensile testing of the hot-rolled sample.Different characterization techniques such as scanning electron microscopy,transmission electron microscopy,electron backscattered diffraction,and X-ray diffraction were used to analyze the microstructural evolution of steel under different strain levels.The steel had a single austenite phase,which was stable during deformation.After hot rolling,annealing twins were observed in the microstructure of the steel.The steel showed an excellent combination of mechanical properties,like a tensile strength of 527 MPa,impact energy of 203 J at−196℃,and an elongation of 67%till fracture.At the initial deformation stage,the dislocations were generated within the austenite grains,entangled and accumulated at the grain boundaries and annealing twin boundaries.Annealing twins participated in plastic deformation and hindered the dislocation movement.As the deformation progressed,the dislocation slip was hindered and produced stress concentration,and the stacking faults evolved into mechanical twins,which released the stress concentration and delayed the necking. 展开更多
关键词 High-manganese steel Austenite grain Tensile deformation Mechanical twin Annealing twin
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