The transjugular intrahepatic portosystemic shunt(TIPS) is an acceptable procedure that has proven benefits in the treatment of patients who have complications from portal hypertension due to liver cirrhosis.Delayed l...The transjugular intrahepatic portosystemic shunt(TIPS) is an acceptable procedure that has proven benefits in the treatment of patients who have complications from portal hypertension due to liver cirrhosis.Delayed liver laceration is a rare complication of the TIPS procedure.We describe a patient with portal hypertension due to liver cirrhosis,who suddenly presented with abdominal hemorrhage and liver laceration 8 d after TIPS.Few reports have described complications after TIPS placement.To the best of our knowledge,this is the first report describing delayed liver laceration.This potential and serious complication appears to be specific and fatal for TIPS in portal hypertension.We advocate careful attention to the technique to avoid this complication,and timely treatment is extremely important.展开更多
In the last few years,the overall incidence of malignant tumors has been increasing in the country.In order to find effective anti-tumor drugs,the development and modification of natural drugs have become the focus of...In the last few years,the overall incidence of malignant tumors has been increasing in the country.In order to find effective anti-tumor drugs,the development and modification of natural drugs have become the focus of domestic and international researchers.Thallus japonica,composed of polysaccharides,minerals,amino acids,natural proteins,and lipids,is a traditional Chinese medicine with the functions of eliminating phlegm and disinhibiting water.At the same time,it has the edible and medicinal efficacy.There are a lot of active components that have been demonstrated to possess diverse biological activities including anti-tumor,anti-viral,anti-coagulant,and anti-bacterial,and so on in thallus japonica.Laminarin,composed of glucose,galactose,fucose and so on,is a common and high molecular weight heteropolysaccharide in brown algae(such as thallus japonica,kelp),and it is a potential anti-tumor drug.However,the lack of biological activity of natural polysaccharides limits the application of polysaccharides,so it is necessary to modify the structure or physical and chemical properties of it to enhance the anti-tumor activity of polysaccharides.In recent years,in order to improve the biological activity of laminarin,domestic and international researchers have introduced some groups on the surface of it.Moreover,use the function of modified groups to cause the changes in physicochemical property,spatial structure,substituent group and molecular weight to improve the anti-tumor activity in vitro and in vivo.Therefore,the structural modification has become the main and powerful means to improve the activity of polysaccharides.展开更多
文摘The transjugular intrahepatic portosystemic shunt(TIPS) is an acceptable procedure that has proven benefits in the treatment of patients who have complications from portal hypertension due to liver cirrhosis.Delayed liver laceration is a rare complication of the TIPS procedure.We describe a patient with portal hypertension due to liver cirrhosis,who suddenly presented with abdominal hemorrhage and liver laceration 8 d after TIPS.Few reports have described complications after TIPS placement.To the best of our knowledge,this is the first report describing delayed liver laceration.This potential and serious complication appears to be specific and fatal for TIPS in portal hypertension.We advocate careful attention to the technique to avoid this complication,and timely treatment is extremely important.
文摘In the last few years,the overall incidence of malignant tumors has been increasing in the country.In order to find effective anti-tumor drugs,the development and modification of natural drugs have become the focus of domestic and international researchers.Thallus japonica,composed of polysaccharides,minerals,amino acids,natural proteins,and lipids,is a traditional Chinese medicine with the functions of eliminating phlegm and disinhibiting water.At the same time,it has the edible and medicinal efficacy.There are a lot of active components that have been demonstrated to possess diverse biological activities including anti-tumor,anti-viral,anti-coagulant,and anti-bacterial,and so on in thallus japonica.Laminarin,composed of glucose,galactose,fucose and so on,is a common and high molecular weight heteropolysaccharide in brown algae(such as thallus japonica,kelp),and it is a potential anti-tumor drug.However,the lack of biological activity of natural polysaccharides limits the application of polysaccharides,so it is necessary to modify the structure or physical and chemical properties of it to enhance the anti-tumor activity of polysaccharides.In recent years,in order to improve the biological activity of laminarin,domestic and international researchers have introduced some groups on the surface of it.Moreover,use the function of modified groups to cause the changes in physicochemical property,spatial structure,substituent group and molecular weight to improve the anti-tumor activity in vitro and in vivo.Therefore,the structural modification has become the main and powerful means to improve the activity of polysaccharides.
