超声乳化人工晶状体植入术治疗高度近视合并白内障患者的疗效

目的:探讨超声乳化人工晶状体植入术治疗高度近视合并白内障患者的疗效。方法:回顾性研究。收集2017-02/2019-01我院行超声乳化联合人工晶状体植入术的高度近视合并白内障患者42例42眼,并按1∶1比例选取同期行超声乳化联合人工晶状体植入术的不合并高度近视的白内障患者42例42眼作为对照组。检查两组患者术前,术后1wk,1、3mo最佳矫正视力(BCVA);记录术前和术后3mo眼压、黄斑中心凹视网膜厚度(CMT)、角膜曲率、角膜散光、前房深度、前房角、房角开放距离、角膜内皮细胞计数、六角细胞比例及手术并发症发生情况。结果:两组患者术后1wk,1、3mo BCVA比较有差异(均P<0.001);术前、术后3mo,高度近视合并白内障组CMT、前房深度、房角开放距离、前房角均高于对照组(P<0.001),两组手术前后眼压比较无差异(P>0.05);术后3mo,高度近视合并白内障患者后表面鼻上角膜曲率较术前增大(P<0.001),对照组后表面中心、颞下角膜曲率较术前大(P<0.001),高度近视合并白内障患者后表面中心、后表面颞下角膜曲率低于对照组(均P<0.05);两组患者术后3mo前表面、后表面角膜散光均上升(均P<0.001),后表面逆规散光较术前增多(P<0.05),但组间比较差异无统计学意义(P>0.05);两组患者术后3mo角膜内皮细胞计数、六角细胞比例均较同组术前降低(P<0.05),高度近视合并白内障术后3mo角膜内皮细胞计数、六角细胞比例低于对照组(均P<0.05);高度近视合并白内障并发症发生率高于对照组,但组间比较无差异(P>0.05)。结论:高度近视合并白内障患者超声乳化联合人工晶状体植入术后视力可获益,但改善效果不及不合并高度近视的白内障患者,高度近视合并白内障患者术后CMT较不合并高度近视的白内障患者更高,后表面散光有所增加,术后前房形态改变更明显,角膜内皮细胞受损更重,但相对安全可靠。

Endotamponades in pars plana vitrectomy for metallic intraocular foreign body associated with endophthalmitis

AIM: To study the criterion-reference of endotamponades in pars plana vitrectomy for metallic intraocular foreign body (MIOFD) associated with endophthalmitis. METHODS:Thirty-six patients of MIOFD with endophthalmitis accorded with Exclusion and inclusion criteria were retrospectively analyzed. A detailed analysis of the patients' natural factors, preoperative examinations, intraoperative endotamponades choice, postoperative complications and therapeutic effects was performed. RESULTS: BSS was used in 4 eyes without obvious retinal damage. There was no postoperative complication and their visual acuity (VA) was improved. Sixteen eyes that had mild retinal damage filled with C3F8 gas. The postoperative VA improved in 10 eyes (62.5%), 4 eyes (25.0%) remained unchanged and 2 eyes (12.5%) decreased. Only 2 cases occurred postoperative retinal detachment in gas group. Another 16 eyes with serious retinal damage were treated with silicone oil. Postoperative VA of 9 eyes (56.3%) improved, 3 eyes (18.8%) remained unchanged and 4 eyes (25.0%) decreased. The silicone oil group had higher incidence of postoperative complications, but the incidence of secondary treatment had no significant different between silicone oil and gas group. CONCLUSION: An appropriate choice of endotamponades in vitrectomy surgery for MIOFB with endophthalmitis is important for prognosis.

Summary and correlation analysis of TCM syndromes in 159 elderly patients with acute myeloid leukemia

Objective:To investigate the characteristics of TCM syndromes in elderly patients with acute myeloid leukemia(AML)at the onset,and to analyze the main syndrome types and their correlation with age,percentage of bone marrow blasts,and genetic prognostic stratification.Methods:A retrospective analysis was performed on 159 AML patients aged over 60 years who were diagnosed and treated in our hospital,and the clinical data were collected and analyzed statistically.Results:In 159 elderly AML patients,the main clinical symptoms were fatigue,poor appetite,conscious fever,and various hemorrhages.The main syndromes were Ying(42.01%),Wei(31.25%),Essential(14.81%)and Blood(11.69%);the syndromes are divided into Qi and Yin deficiency(32.70%),Qi and blood deficiency(30.19%),true Yin deficiency(28.03%)and Qi heat and blood(8.81%).The age difference between the two groups was statistically significant(P<0.001),and the multiple comparison results showed that the age of the Qi-blood deficiency group was younger than the true-Yin deficiency group and the Qi-Yin deficiency group;the percentage of bone marrow blasts was statistically significant in the three groups at the initial diagnosis(P<0.05),multiple comparison results showed that the percentage of bone marrow blasts in the true Yin deficiency group was higher than that in the Qi-blood deficiency group and the Qi-Yin deficiency group;the genetic prognostic stratification of the three groups was statistically significant(P<0.05),multiple comparisons.The results showed that the genetic prognosis of the true Yin deficiency group was poorer than that of the Qi and blood deficiency group and the Qi and Yin deficiency group.Conclusion:The most common clinical symptoms of elderly AML patients are fatigue,the disease is located in the bone marrow,and the disease is Ying,Wei,essence,and blood.With the increase in the patient's age,the TCM syndrome types tend to be more insufficiency of true Yin and deficiency of both Qi and Yin,and the prognosis of patients with insufficiency of true Yin is poor.It provides a directional scientific basis for the treatment of senile AML with integrated traditional Chinese and Western medicine.