Herein,we report rhodium catalyzed N-arylation via addition of arylboronic acids to electron-deficientα-iminoesters which can be prepared in high efficiency by using easily accessible B-carbonyl esters.The reaction i...Herein,we report rhodium catalyzed N-arylation via addition of arylboronic acids to electron-deficientα-iminoesters which can be prepared in high efficiency by using easily accessible B-carbonyl esters.The reaction is highly regiospecific to achieve the N-aryl addition efficiently with up to 99%yield under mild conditions.The corresponding product can be further efficiently converted into indoles andaseries of other important building blocks.展开更多
基金financial support from the Natural Science Foundation of Shanghai(20zR1405500).
文摘Herein,we report rhodium catalyzed N-arylation via addition of arylboronic acids to electron-deficientα-iminoesters which can be prepared in high efficiency by using easily accessible B-carbonyl esters.The reaction is highly regiospecific to achieve the N-aryl addition efficiently with up to 99%yield under mild conditions.The corresponding product can be further efficiently converted into indoles andaseries of other important building blocks.
