Dear Editor,Pseudomonas aeruginosa is an opportunistic Gram-negative bacterium that causes a series of life-threatening acute and/or chronic infections in humans,often in persons with immunodeficiency.P.aeruginosa has...Dear Editor,Pseudomonas aeruginosa is an opportunistic Gram-negative bacterium that causes a series of life-threatening acute and/or chronic infections in humans,often in persons with immunodeficiency.P.aeruginosa has been listed as one of the priority bacteria that requires extensive research and urgent development of new antibiotic treatments by the World Health Organization(WHO)in 2017.1 In recent years,numerous studies have shown that miRNAs play an important role in infection and inflammatory responses.2,3 Our earlier researches suggest that miRNAs are a key regulator of the inflammatory responses and are involved in the clearance of P.aeruginosa in vitro and in vivo.展开更多
基金supported by the National Natural Science Foundation of China(Grant No.81671551)the Sichuan Science and Technology Program(Grant No.2020YFQ0022)+1 种基金West China Hospital(Grant No.HX-2019-nCoV-17)Wenzhou Institute University of Chinese Academy of Sciences,and Southwest Medical University。
文摘Dear Editor,Pseudomonas aeruginosa is an opportunistic Gram-negative bacterium that causes a series of life-threatening acute and/or chronic infections in humans,often in persons with immunodeficiency.P.aeruginosa has been listed as one of the priority bacteria that requires extensive research and urgent development of new antibiotic treatments by the World Health Organization(WHO)in 2017.1 In recent years,numerous studies have shown that miRNAs play an important role in infection and inflammatory responses.2,3 Our earlier researches suggest that miRNAs are a key regulator of the inflammatory responses and are involved in the clearance of P.aeruginosa in vitro and in vivo.