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Overexpressed miR-539 exacerbates Pseudomonas aeruginosa puenmonia by promoting inflammatory responses 被引量:1
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作者 Jianbo Li Qi Yang +6 位作者 xinghong gao Feng Chen Xinxia Gu Xikun Zhou Lei Chen Jie Liu Min Wu 《Precision Clinical Medicine》 2023年第2期113-115,共3页
Dear Editor,Pseudomonas aeruginosa is an opportunistic Gram-negative bacterium that causes a series of life-threatening acute and/or chronic infections in humans,often in persons with immunodeficiency.P.aeruginosa has... Dear Editor,Pseudomonas aeruginosa is an opportunistic Gram-negative bacterium that causes a series of life-threatening acute and/or chronic infections in humans,often in persons with immunodeficiency.P.aeruginosa has been listed as one of the priority bacteria that requires extensive research and urgent development of new antibiotic treatments by the World Health Organization(WHO)in 2017.1 In recent years,numerous studies have shown that miRNAs play an important role in infection and inflammatory responses.2,3 Our earlier researches suggest that miRNAs are a key regulator of the inflammatory responses and are involved in the clearance of P.aeruginosa in vitro and in vivo. 展开更多
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