Lactic acid and otherα-hydroxycarboxylic acids(α-HCAs)play crucial roles in various applications.Synthesizingα-HCAs from biomass platform feedstocks such as ethylene glycol(EG)and primary alcohols is novel and attr...Lactic acid and otherα-hydroxycarboxylic acids(α-HCAs)play crucial roles in various applications.Synthesizingα-HCAs from biomass platform feedstocks such as ethylene glycol(EG)and primary alcohols is novel and attractive.It was reported that the dehydrogenative cross-coupling of EG and primary alcohols can be achieved via homogeneous catalysis.Herein,we report a heterogeneous catalytic strategy to produce a series ofα-HCAs through the same reaction pathway.Impressive catalytic activity and selectivity were achieved using various metals(Ru,Ir,Pt and Pd)supported on the nanodiamond-graphene(ND@G),with Ru exhibiting the best performance.This universally applicable process enables the easy synthesis of gram-scaleα-HCAs,providing a straightforward and compelling C–C bond cross-coupling strategy for the utilization of alcohols derived from biomass feedstocks.展开更多
基金financial support from the National Key R&D Program of China(2022YFA1504800)the Natural Science Foundation of China(22005007,21725301,22232001)+3 种基金China National Petroleum Corporation-Peking University Strategic Cooperation Project of Fundamental Researchthe New Cornerstone Science Foundationsupport from the Beijing Outstanding Young Scientist Program(BJJWZYJH01201914430039)support from the Tencent Foundation through the XPLORER PRIZE。
文摘Lactic acid and otherα-hydroxycarboxylic acids(α-HCAs)play crucial roles in various applications.Synthesizingα-HCAs from biomass platform feedstocks such as ethylene glycol(EG)and primary alcohols is novel and attractive.It was reported that the dehydrogenative cross-coupling of EG and primary alcohols can be achieved via homogeneous catalysis.Herein,we report a heterogeneous catalytic strategy to produce a series ofα-HCAs through the same reaction pathway.Impressive catalytic activity and selectivity were achieved using various metals(Ru,Ir,Pt and Pd)supported on the nanodiamond-graphene(ND@G),with Ru exhibiting the best performance.This universally applicable process enables the easy synthesis of gram-scaleα-HCAs,providing a straightforward and compelling C–C bond cross-coupling strategy for the utilization of alcohols derived from biomass feedstocks.
