background Evidence on the natural angiographic course of moyamoya disease(MMD)is lacking.It takes about 6 months for waiting for revascularisation surgery.The issue of when to perform subtraction angiography(DSA)for ...background Evidence on the natural angiographic course of moyamoya disease(MMD)is lacking.It takes about 6 months for waiting for revascularisation surgery.The issue of when to perform subtraction angiography(DSA)for follow-up remains unclear.We investigated the natural course of MMD by DSA and attempted to determine the best interval to perform the follow-up DSA.Methods This is a single-centre cohort study of Chinese MMD inpatients treated from 1 January 2015 to 31 August 2019.Their angiographic findings were evaluated on Suzuki stage and collateral circulation between two follow-ups of the same hemisphere.results A total of 110 patients who met the criteria were enrolled in this study.After a median 6 months follow-up,five patients(4.5%)had progression,four females and one male.Time interval of progression ranged from 4 to 137 months with a mean of 61.4 months.Of five patients with progression,four had unilateral lesion(two ipsilateral and two contralateral)and one had bilateral lesions.Collateral circulation was changed in three of five patients.Conclusions The angiographic evidence of progression in MMD was rare in the short-term follow-up,and most patients with progression had initial unilateral involvement.DSA re-examination may be not needed in patients with bilateral MMD,but needed in unilateral MMD.展开更多
基金supported by the National Key Technology Research and Development Programme of the Ministry of Science and Technology of China(grants 2006BAI01A13 and 2015BAI12B04)Beijing Municipal Organisation Department Talents Project(grant 2015000021469 G219)+1 种基金Beijing Municipal ST Commission(grant D161100003816005)National Natural Science Foundation of China(grant 81701137).
文摘background Evidence on the natural angiographic course of moyamoya disease(MMD)is lacking.It takes about 6 months for waiting for revascularisation surgery.The issue of when to perform subtraction angiography(DSA)for follow-up remains unclear.We investigated the natural course of MMD by DSA and attempted to determine the best interval to perform the follow-up DSA.Methods This is a single-centre cohort study of Chinese MMD inpatients treated from 1 January 2015 to 31 August 2019.Their angiographic findings were evaluated on Suzuki stage and collateral circulation between two follow-ups of the same hemisphere.results A total of 110 patients who met the criteria were enrolled in this study.After a median 6 months follow-up,five patients(4.5%)had progression,four females and one male.Time interval of progression ranged from 4 to 137 months with a mean of 61.4 months.Of five patients with progression,four had unilateral lesion(two ipsilateral and two contralateral)and one had bilateral lesions.Collateral circulation was changed in three of five patients.Conclusions The angiographic evidence of progression in MMD was rare in the short-term follow-up,and most patients with progression had initial unilateral involvement.DSA re-examination may be not needed in patients with bilateral MMD,but needed in unilateral MMD.
