[Objectives]To determine the optimal reflux extraction process conditions for Compound Coptis Ointment.[Methods]The study employed the orthogonal experimental design method and drug-sensitive disc agar diffusion metho...[Objectives]To determine the optimal reflux extraction process conditions for Compound Coptis Ointment.[Methods]The study employed the orthogonal experimental design method and drug-sensitive disc agar diffusion method to evaluate the extraction rate,berberine hydrochloride content,and bacteriostatic ring diameter of the extract as comprehensive indices,and optimized the extraction process conditions of Compound Coptis Ointment using ethanol reflux.[Results]Based on the results of comprehensive indices,the optimal reflux extraction conditions for Compound Coptis Ointment were determined to be soaking in 1.5 times the amount of 70%ethanol for 2 h,followed by two extractions with 6 times the amount of 70%ethanol for 1 h each time.Three verification tests were conducted under the optimal process conditions.The yield of the extract was 28.32%±0.53%,the content of berberine hydrochloride was 4.68%±0.45%,and the diameter of the bacteriostatic ring was(2.5±0.2)cm.[Conclusions]The extract had higher drug content and exhibited better antibacterial effects.The optimized extraction process is simple,stable,and reliable,and can be effectively used to optimize the extraction process of Compound Coptis Ointment.展开更多
With the development of social economy and radiotherapy technique,proton/heavy ion radiotherapy has been applied widely to clinical practices.At present,there are at least 29 hospitals in China at various stages of pl...With the development of social economy and radiotherapy technique,proton/heavy ion radiotherapy has been applied widely to clinical practices.At present,there are at least 29 hospitals in China at various stages of planning,construction,commissioning or clinical operation of medical proton/heavy ion beam radiotherapy equipment.Compared with common radiotherapy accelerators used in conventional external beam radiotherapy,the proton/heavy ion therapy system has more stringent requirements for quality control so as to achieve an optimum therapeutic effect.In order to protect the health rights of patients undergoing radiotherapy,to facilitate the relevant administrative supervision departments to carry out standard-based approval and routine supervision and to promote the development of related medical undertakings,the standard for testing of quality control for medical proton/heavy ion beam radiotherapy equipment is drafted to fill the gap in this regard in China and even worldwide.The standard contains five indicators and corresponding testing methods for radiological protection and safety and 16 indicators for quality control of equipment performance.The standard is a mandatory standard and is based on the relevant Chinese legal requirements for the testing of radiotherapy equipment,so all the indicators listed in the standard shall be tested.During the drafting of the standard,the opinions from hospitals that are currently using proton/heavy ion medical accelerators for radiotherapy purpose and from the related equipment manufacturers were taken into account.The draft standard was revised with reference to these opinions and the feasibility of the related quality control requirements.The official version of the standard was released on March 7,2023,and implementation is scheduled to begin on March 1,2024.展开更多
We present a multiview method for markerless motion capture of multiple people. The main challenge in this problem is to determine crossview correspondences for the 2 D joints in the presence of noise. We propose a 3 ...We present a multiview method for markerless motion capture of multiple people. The main challenge in this problem is to determine crossview correspondences for the 2 D joints in the presence of noise. We propose a 3 D hypothesis clustering technique to solve this problem. The core idea is to transform joint matching in 2 D space into a clustering problem in a 3 D hypothesis space. In this way, evidence from photometric appearance, multiview geometry, and bone length can be integrated to solve the clustering problem efficiently and robustly. Each cluster encodes a set of matched 2 D joints for the same person across different views, from which the 3 D joints can be effectively inferred. We then assemble the inferred 3 D joints to form full-body skeletons for all persons in a bottom–up way. Our experiments demonstrate the robustness of our approach even in challenging cases with heavy occlusion,closely interacting people, and few cameras. We have evaluated our method on many datasets, and our results show that it has significantly lower estimation errors than many state-of-the-art methods.展开更多
基金supported by the National Natural Science Foundation of China(No.11274205,No.11274206,and No.11504206)Natural Science Foundation of Shandong Province(ZR2022MA016,ZR2020ME231)Key Research and Development Project of Shan-dong province(No.2019GGX102050).
基金Supported by Key Research Project of Wuhan Municipal Health Commission(WZ21A08).
文摘[Objectives]To determine the optimal reflux extraction process conditions for Compound Coptis Ointment.[Methods]The study employed the orthogonal experimental design method and drug-sensitive disc agar diffusion method to evaluate the extraction rate,berberine hydrochloride content,and bacteriostatic ring diameter of the extract as comprehensive indices,and optimized the extraction process conditions of Compound Coptis Ointment using ethanol reflux.[Results]Based on the results of comprehensive indices,the optimal reflux extraction conditions for Compound Coptis Ointment were determined to be soaking in 1.5 times the amount of 70%ethanol for 2 h,followed by two extractions with 6 times the amount of 70%ethanol for 1 h each time.Three verification tests were conducted under the optimal process conditions.The yield of the extract was 28.32%±0.53%,the content of berberine hydrochloride was 4.68%±0.45%,and the diameter of the bacteriostatic ring was(2.5±0.2)cm.[Conclusions]The extract had higher drug content and exhibited better antibacterial effects.The optimized extraction process is simple,stable,and reliable,and can be effectively used to optimize the extraction process of Compound Coptis Ointment.
文摘With the development of social economy and radiotherapy technique,proton/heavy ion radiotherapy has been applied widely to clinical practices.At present,there are at least 29 hospitals in China at various stages of planning,construction,commissioning or clinical operation of medical proton/heavy ion beam radiotherapy equipment.Compared with common radiotherapy accelerators used in conventional external beam radiotherapy,the proton/heavy ion therapy system has more stringent requirements for quality control so as to achieve an optimum therapeutic effect.In order to protect the health rights of patients undergoing radiotherapy,to facilitate the relevant administrative supervision departments to carry out standard-based approval and routine supervision and to promote the development of related medical undertakings,the standard for testing of quality control for medical proton/heavy ion beam radiotherapy equipment is drafted to fill the gap in this regard in China and even worldwide.The standard contains five indicators and corresponding testing methods for radiological protection and safety and 16 indicators for quality control of equipment performance.The standard is a mandatory standard and is based on the relevant Chinese legal requirements for the testing of radiotherapy equipment,so all the indicators listed in the standard shall be tested.During the drafting of the standard,the opinions from hospitals that are currently using proton/heavy ion medical accelerators for radiotherapy purpose and from the related equipment manufacturers were taken into account.The draft standard was revised with reference to these opinions and the feasibility of the related quality control requirements.The official version of the standard was released on March 7,2023,and implementation is scheduled to begin on March 1,2024.
基金partially supported by National Natural Science Foundation of China(No.61872317)Face Unity Technology。
文摘We present a multiview method for markerless motion capture of multiple people. The main challenge in this problem is to determine crossview correspondences for the 2 D joints in the presence of noise. We propose a 3 D hypothesis clustering technique to solve this problem. The core idea is to transform joint matching in 2 D space into a clustering problem in a 3 D hypothesis space. In this way, evidence from photometric appearance, multiview geometry, and bone length can be integrated to solve the clustering problem efficiently and robustly. Each cluster encodes a set of matched 2 D joints for the same person across different views, from which the 3 D joints can be effectively inferred. We then assemble the inferred 3 D joints to form full-body skeletons for all persons in a bottom–up way. Our experiments demonstrate the robustness of our approach even in challenging cases with heavy occlusion,closely interacting people, and few cameras. We have evaluated our method on many datasets, and our results show that it has significantly lower estimation errors than many state-of-the-art methods.
