Gastroesophageal reflux disease(GERD)is a widely prevalent gastrointestinal disorder,affecting13.3%of the global population.There are shortages and limitations of current GERD treatment modalities,and complementary an...Gastroesophageal reflux disease(GERD)is a widely prevalent gastrointestinal disorder,affecting13.3%of the global population.There are shortages and limitations of current GERD treatment modalities,and complementary and alternative therapy(CAT)is a promising option to fill in the gap.Dietary and lifestyle modifications might play an important and complementary role in alleviating GERD symptoms.Traditional Chinese medicine and brain–gut behavior therapy,particularly transcutaneous electrical acustimulation and diaphragmatic breathing therapy were shown to be useful adjuncts or alternatives in treating GERD.CAT may help to relieve GERD symptoms,minimize medication dosage,and slow the demand for surgery.The aim of this review was to summarize the existing evidence of some common CATs in treating symptomatic GERD,including dietary modification,lifestyle change,traditional Chinese medicine,and brain–gut behavior therapy.展开更多
To the Editor:Glioma is a highly invasive and lethal heterogeneous disease caused by glial or precursor cell mutation.It accounts for about 50%of tumors in children and 80%of malignant tumors.[1]The nucleotide excisio...To the Editor:Glioma is a highly invasive and lethal heterogeneous disease caused by glial or precursor cell mutation.It accounts for about 50%of tumors in children and 80%of malignant tumors.[1]The nucleotide excision repair(NER)pathway is a process that involves the sequential assembly of many proteins,including excision repair cross complementation group 1(ERCC1)and xeroderma pigmentosum complementation group F(XPF,also known as ERCC4).展开更多
基金supported by the National Natural Science Foundation of China[grant numbers 82170577 and 81970479].
文摘Gastroesophageal reflux disease(GERD)is a widely prevalent gastrointestinal disorder,affecting13.3%of the global population.There are shortages and limitations of current GERD treatment modalities,and complementary and alternative therapy(CAT)is a promising option to fill in the gap.Dietary and lifestyle modifications might play an important and complementary role in alleviating GERD symptoms.Traditional Chinese medicine and brain–gut behavior therapy,particularly transcutaneous electrical acustimulation and diaphragmatic breathing therapy were shown to be useful adjuncts or alternatives in treating GERD.CAT may help to relieve GERD symptoms,minimize medication dosage,and slow the demand for surgery.The aim of this review was to summarize the existing evidence of some common CATs in treating symptomatic GERD,including dietary modification,lifestyle change,traditional Chinese medicine,and brain–gut behavior therapy.
基金supported by grants from the National Natural Science Foundation of China(No.81802346)the China Postdoctoral Science Foundation(Nos.2020T130132,2020M682668)
文摘To the Editor:Glioma is a highly invasive and lethal heterogeneous disease caused by glial or precursor cell mutation.It accounts for about 50%of tumors in children and 80%of malignant tumors.[1]The nucleotide excision repair(NER)pathway is a process that involves the sequential assembly of many proteins,including excision repair cross complementation group 1(ERCC1)and xeroderma pigmentosum complementation group F(XPF,also known as ERCC4).