Nardelli et al.(1)conducted a multi-center observational study to assess the mortality risk in patients with and without overt hepatic encephalopathy(HE)after transjugular intrahepatic portosystemic shunt(TIPS).In the...Nardelli et al.(1)conducted a multi-center observational study to assess the mortality risk in patients with and without overt hepatic encephalopathy(HE)after transjugular intrahepatic portosystemic shunt(TIPS).In their paper,the authors disclosed that post-TIPS overt HE was not linked to an increased risk of mortality in patients with cirrhosis during a median follow-up of 30 months(1).However,many other studies have reported that post-TIPS HE is significantly associated with a higher risk of mortality based on long-term follow-up in patients with cirrhosis(2-6).Given this inconsistency,we conducted a meta-analysis to evaluate the association between post-TIPS HE and mortality,using both unadjusted and adjusted effect estimates in patients with cirrhosis.展开更多
基金Xi’an Science and Technology Plan Project(22YXYJ0122).
文摘Nardelli et al.(1)conducted a multi-center observational study to assess the mortality risk in patients with and without overt hepatic encephalopathy(HE)after transjugular intrahepatic portosystemic shunt(TIPS).In their paper,the authors disclosed that post-TIPS overt HE was not linked to an increased risk of mortality in patients with cirrhosis during a median follow-up of 30 months(1).However,many other studies have reported that post-TIPS HE is significantly associated with a higher risk of mortality based on long-term follow-up in patients with cirrhosis(2-6).Given this inconsistency,we conducted a meta-analysis to evaluate the association between post-TIPS HE and mortality,using both unadjusted and adjusted effect estimates in patients with cirrhosis.
