Characteristics Analysis of Chemical Concentration Sensor Based on Three-layer FBG

The three-layer structure model of the fiber Bragg grating is proposed in this paper. And through experimental study and reasoning calculation to verify the three layer structure of the optical waveguide model, so the sensitivity characteristic of the Bragg wavelength to the refractive index of chemical solution is obtained. And the relationships between the concentration and the shift of Bragg wavelength of sucrose, ethanol, and Nacl solution are achieved. Finally the shifts of the Bragg wavelength with the external concentration are obtained by experiments. A kind of simple structure, small size, good stability, high sensitivity chemical concentration sensor is obtained.

The Value of c-TCD in the Diagnosis of Migraine and Cryptogenic Stroke Caused by PFO

Objective:To investigate the value of contrast-enhanced transcranial doppler(c-TCD)in the diagnosis of patent foramen ovale(PFO)of patients with migraine and cryptogenic stroke.Methods:A retrospective analysis of 160 patients undergoing c-TCD monitoring in our hospital from June 2014 to June 2019 was performed.Among them,there were 80 cases of patients with migraine(38 cases with aura and 42 cases without aura)in group A,and 80 cases of patients with cryptogenic stroke in group B.The positive detectable rate of PFO in the two groups were calculated and analyzed.Results:The detectable rate was 50.00%in group A,and 40.00%in group B.There was no statistical significance between the two groups(P>0.05).Among them,the detectable rate of PFO in migraine with aura in group A(62.50%)was higher than that in group B(37.50%).The difference was statistically significant(P<0.05);In the two groups of PFO-positive patients,the difference didn’t have statistical significance,comparing the proportion of the inherent type to that of potential type(P>0.05);There was no statistical significance of the difference between the RLS incidence of grade I and that of grade II among two groups of PFO-positive patients(P>0.05);the incidence of RLS in grade III in group B(50.00%)was higher than that in group A(25.00%),and the difference was statistically significant(P<0.05).Conclusion:c-TCD can accurately screen migraine and cryptogenic stroke caused by PFO,and grade and classify it as a clinical diagnosis of migraine and cryptogenic caused by PFO.It can also act as a objective reference of estimating the effect of treatment in different diseases and preventing cryptogenic stroke.

The Value of the Wearable Single-lead Remote Monitoring Device with the Scatterplot in Chronic Disease Management

Objective:To study the value of the wearable single-lead remote monitoring device with the scatterplot in chronic disease management.Methods:dmitted into 435 residents accord with the inclusion criteria of 20 primary medical institutions of Yinchuan city,and grouped voluntarily by the implementation schemes were grouped voluntarily according to the implementation schemes.According to one of the three implementation schemes selected,the general practitioner guided the subjects to take on the wearable single-lead remote monitoring device,collecting and uploading the EEG data,then diagnosed and analyzed by the synchronously generated ECG scatterplot,finally,summarized the incidence and the categories,analyzed the differences among these three groups.Results:Among 435 subjects,there were 61 normal patients and 374 arrhythmias with the detection rate of 85.98%;and among the 1672 data collected,there were 606 normal data and 1066 arrhythmia with the detection rate of 63.76%;880 data in total 333 cases with atrial premature beat;442 data in total 215 cases with occasional ventricular premature beat;37 data of 22 cases with frequent atrial beat;65 data of 28 cases with frequent ventricular premature beat;13 data of 6 cases with atrial fibrillation;25 data of 15 cases with excitation conduction disorder;2 data of 2 cases with atrial flutter;31 data of 19 cases with ventricular tachycardia;30 data of 16 cases with conduction block;and 14 data of 8 cases with Para systolic rhythm.comparing the detection rate of arrhythmia in three groups,the difference was not statistically significant(P>0.05).Conclusion:The wearable singlelead remote monitoring device with the scatterplot has high application value in cardiovascular chronic disease management.Its effectively screening,validly diagnosing and detailed classifying are helpful to the early intervention,and the protection of the patients’lives.

结直肠癌患者奥沙利铂化疗致外周神经毒性单因素分析及其防治策略

目的:分析奥沙利铂治疗结直肠癌患者所致神经毒性的相关因素并探讨应对策略。方法:采用方便抽样的方法,选取2018年1月至2020年12月浙江省肿瘤医院收治的结直肠癌且使用奥沙利铂化疗的患者300例进行基线调查,统计患者外周神经毒性(OIPN)发生情况,采用单因素分析奥沙利铂致患者OIPN的影响因素。结果:患者OIPN评分在性别、学历、职业、长期居住地差异均有统计学意义(t=7.29、3.39、2.53、18.11,均P<0.05);而在宗教、婚姻、同住成员、医疗付费、是否有吸烟史因素,得分差异均无统计学意义(t=3.25、0.37、0.69、2.39、0.15,均P>0.05)。而患者的疾病资料中,肿瘤TNM分期、不同静脉通路、奥沙利铂累积量,差异均有统计学意义(t=8.40、3.34、3.49,均P<0.05)。结论:医务人员需重视结直肠癌使用奥沙利铂治疗患者OIPN的发生情况,关注患者自身与疾病相关因素,及时采取正确的有效的应对策略,以减轻患者不良反应,改善生活质量,确保治疗效果。